BibTex RIS Cite

A comparison of the histopathological results of thyroid nodule biopsy applied with ultrasound-guided traditional technique fine needle aspiration and a novel dual-injector model fine needle aspiration

Year 2019, Volume: 8 Issue: 3, 147 - 154, 01.09.2019

Çağlayan Çakır

https://doi.org/10.5505/abantmedj.2019.76258

Abstract

INTRODUCTION: To compare the cytological aspects of traditional ultrasound guided fine needle aspiration biopsy FNAB with the newly developed dual injector model, as the measurement of successMETHODS: A total of 130 thyroid nodules Group 1 were applied with ultrasound-guided fine needle aspiration biopsy with two needles at the same time. This technique was designed in a computer environment and a 3D printed dual injector model was applied to the patient group between December 2017-May 2018. The histopathological results of the obtained materials were statistically compared with the results of 169 Group 2 thyroid nodule FNAB biopsies using a single needle, which is the ultrasound-guided traditional method. Cytological diagnoses were based on the Bethesda classification and ultrasonography findings of the cases were recorded within the specified criteria.RESULTS: No difference was determined in the malignant positive /benign negative ratios of the evaluated cases in Group 1 4/99 and Group 2 5/133 p = 0.581 . In Group 1, the diagnosis was incorrect in 14.62% 19/130 and correct in 85.38% 111/130 of cases. In Group 2, the diagnosis was incorrect in 12.43 21/169 and correct in 87.57% 148/169 of cases. For the whole sample, these rates were 13.4% 40/299 incorrect and 86.6% 259/299 correctly.DISCUSSION AND CONCLUSION: The results of this study showed succesful method in the results of thyroid biopsies made using the binary injector model that was developed in a computer.

Keywords

Thyroid Aspiration biopsy Thyroid nodules

References

  • Kelly NP, Um JC, DeJong S, Harmath C, Dudiak C, Wojcik EM. Specimen adequacy and diagnostic specificity of ultrasound- guided fine needle aspirations of nonpalpable thyroid nodules. Diagn Cytopathol 2006; 34:188-90
  • Nabriski D, Ness-Abramof R, Brosh TO, Konen O, Shapiro MS, Shenkman L. Clinical relevance of non-palpabl thyroid nodules as assessed by ultrasound-guided fine needle aspiration biopsy. J Endocrinol Invest. 2003; 26:3-4
  • Davies L, Welch HG. Current thyroid cancer trends in the United States. JAMA Otolaryngol Head Neck Surg 2014;140:317-22
  • Cai XJ, Valiyaparambath N, Nixon P,Waghorn A, Giles T, Helliwell T. Ultrasoundguided fine needle aspiration cytology in the diagnosis and managment of thyroid nodules. Cytopathology 2006;17:251-6
  • Koike E, Noguchi S, Yamashita H, Murakami T, Ohshima A, Kawamoto H et al. Ultrasonographic characteristics of thyroid nodules: prediction of malignancy. Arch Surg. 2001;136:334- 7
  • Frates MC, Benson CB, Charboneau JW, Cibas ES, Clark OH, Coleman BG et al. Society of Radiologists in Ultrasound: Management of thyroid nodules detected at US: Society of Radiologists in Ultrasound consensus conference statement. Radiology. 2005; 237:794-800
  • Chan BK, Desser TS, McDougall IR, Weigel RJ, Jeffrey RB Jr (2003) Common and uncommon sonographic features of papillary thyroid carcinoma. J Ultrasound Med 22:1083-90
  • Iannuccilli JD, Cronan JJ, Monchik JM. Risk for malignancy of thyroid nodules as assessed by sonographic criteria: the need for biopsy. J Ultrasound Med 2004; 23:1455-64
  • Papini E, Guglielmi R, Bianchini A. Risk of malignancy in nonpalpable thyroid nodules: predictive value of ultrasound and color-Doppler features. J Clin Endocrinol Metab 2002; 87:1941-6.
  • Corrias A, Einaudi S, Chiorboli E. Accuracy of fine needle aspiration biopsy of thyroid nodules in detecting malignancy in childhood: comparison with conventional clinical, laboratory, and imaging approaches. J Clin Endocrinol Metab 2001; 86:4644-8
  • Kwak JY, Han KH, Yoon JH, Moon HJ, Son EJ, Park SH et al. Thyroid imaging reporting and data system for US features of nodules: a step in establishing better stratification of cancer risk. Radiology 2011; 260:892–9.
  • Salmaslioglu A, Erbil Y, Dural C, Issever H, Kapran Y, Ozarmagan S et al. Predictive value of sonographic features in preoperative evaluation of malignant thyroid nodules in a multinodular goiter. World J Surg 2008; 32:1948–54.
  • Gul K, Ersoy R, Dirikoc A, Korukluoglu B, Ersoy PE, Aydin R et al. Ultrasonographic evaluation of thyroid nodules: comparison histopathological findings. Endocrine 2009; 36:464–72.
  • Frates MC, Benson CB, Doubilet PM, Kunreuther E, Contreras M, Cibas ES et al. Prevalence and distribution of carcinoma in patients with solitary and multiple thyroid nodules on sonography. J Clin Endocrinol Metab 2006: 91:3411-7 cytological, and
  • Nam-Goong IS, Kim HY, Gong G, Lee HK, Hong SJ, Kim WB et al. Ultrasonography-guided fineneedle aspiration of thyroid incidentaloma: correlation with pathological findings. Clin Endocrinol 2004: 60:21–8
  • Henrichsen TL, Reading CC, Charboneau JW, Donovan DJ, Sebo TJ, Hay ID. Cystic change in thyroid carcinoma: prevalence and estimated volume in 360 carcinomas. J Clin Ultrasound 2010; 38:361–6
  • Gharib H, Goellner JR. Fine-needle aspiration biopsy of the thyroid: Ann Intern Med. 1993; 118:282-9
  • Hamberger B, Gharib H, Melton LJ 3rd, Goellner JR, Zinsmeister AR. Fine-needle aspiration biopsy of thyroid nodules: impact on thyroid practice and cost of care. Am J Med 1982; 73:381-4
  • Danese D, Sciacchitano S, Farsetti A, Andreoli M, Pontecorvi A. Diagnostic accuracy of conventional versus sonography- guided fine-needle aspiration biopsy of thyroid nodules. Thyroid 1998; 8:15–21.
  • Carmeci C, Jeffrey RB, McDougall IR, Nowels KW, Weigel RJ. Ultrasound-guided fine-needle aspiration biopsy of thyroid masses. Thyroid 1998; 8:283–9.
  • Stangierski A, Wolinski K, Martin K, Leitgeber O, RuchalaM. Core needle biopsy of thyroid nodules - evaluation of diagnostic utility and pain experience. Neuro Endocrinol Lett 2013; 34:798–801
  • Nasrollah N, Trimboli P, Rossi F et al. Patient’s comfort with and tolerability of thyroid core needle biopsy. Endocrine 2013; 45:79–83
  • Papini E, Guglielmi R, Bianchini A, Crescenzi A, Taccogna S, Nardi F et al. CM. Risk of malignancy in nonpalpable thyroid nodules: predictive value of ultrasound and color Doppler features. J Clin Endocrinol Metab 2002; 87:1941-6
  • Kuma K, Matsuzuka F, Yokozawa T, Miyauchi A, Sugawara M. Fate of untreated benign thyroid nodules: results of long- term follow-up. World J Surg. 1994; 18:495-8
  • Rumack CM, Wilson SR, Charboneau JW. Diagnostic Ultrasound Third edition. Mosby 2005 (1):736-43.

Tiroid Nodüllerinin İnce İğne Aspirasyon Biyopsisinde İkili Enjektör Modelinin Geleneksel Teknik ile Histopatolojik Sonuçlarının Karşılaştırılması

Year 2019, Volume: 8 Issue: 3, 147 - 154, 01.09.2019

Çağlayan Çakır

https://doi.org/10.5505/abantmedj.2019.76258

Abstract

GİRİŞ ve AMAÇ: Çalışmamızda Ultrasonografi USG kılavuzluğunda geleneksel ince iğne aspirasyon biyopsisi İİAB ve yeni geliştirmiş olduğumuz ikili enjektör modeli ile İİAB işleminin başarı düzeyinin ölçülmesi çalışmamızın amacını oluşturmaktadır.YÖNTEM ve GEREÇLER: Aralık 2017-Mayıs 2018 tarihleri arasında klinisyen istemiyle tarafımıza yönlendirilen tiroid nodülü olan hasta grubunda bilgisayar ortamında tasarladığımız ve 3 boyutlu yazıcıdan çıktısını aldığımız ikili enjektör modeliyle USG klavuzluğunda aynı anda iki iğne ile 130 nodülden Grup 1 ince iğne aspirasyon biyopsisi yaptık. Alınan materyallerin histopatolojik sonuçlarını geleneksel yöntem olan tek iğne kullanılarak yine USG eşliğinde yapılan 169 Grup 2 adet İİAB sonuçları ile istatistiksel olarak karşılaştırdık. Sitolojik tanılar Bethesda sınıflaması baz alınarak yapılmış olup olguların ultrasonografi bulguları belirlenen kriterler dahilinde kaydedilmiştir.BULGULAR: Değerlendirilen olguların malign pozitif /benign negatif oranları, Grup 1 4/99 ile Grup 2 5/133 arasında farklı değildi p= 0,581 . Değerlendirmeye alınan Grup 1 olgularının %14,62 19/130 ’i yanlış, %85.38 111/130 ’u doğru, Grup 2 olgularının 12,43 21/169 ’ü yanlış, %87.57 148/169 ’si doğru, toplam %13,4 40/299 yanlış, %86,6 259/299 ’i doğru bulunmuştur.TARTIŞMA ve SONUÇ: Çalışmamızda ikili enjektör modeli kullanılarak yapılan tirod biyopsisi başarılı bir metod olarak bulunmuştur.

Keywords

Tiroid Aspirasyon biyopsisi Tiroid nodülü

References

  • Kelly NP, Um JC, DeJong S, Harmath C, Dudiak C, Wojcik EM. Specimen adequacy and diagnostic specificity of ultrasound- guided fine needle aspirations of nonpalpable thyroid nodules. Diagn Cytopathol 2006; 34:188-90
  • Nabriski D, Ness-Abramof R, Brosh TO, Konen O, Shapiro MS, Shenkman L. Clinical relevance of non-palpabl thyroid nodules as assessed by ultrasound-guided fine needle aspiration biopsy. J Endocrinol Invest. 2003; 26:3-4
  • Davies L, Welch HG. Current thyroid cancer trends in the United States. JAMA Otolaryngol Head Neck Surg 2014;140:317-22
  • Cai XJ, Valiyaparambath N, Nixon P,Waghorn A, Giles T, Helliwell T. Ultrasoundguided fine needle aspiration cytology in the diagnosis and managment of thyroid nodules. Cytopathology 2006;17:251-6
  • Koike E, Noguchi S, Yamashita H, Murakami T, Ohshima A, Kawamoto H et al. Ultrasonographic characteristics of thyroid nodules: prediction of malignancy. Arch Surg. 2001;136:334- 7
  • Frates MC, Benson CB, Charboneau JW, Cibas ES, Clark OH, Coleman BG et al. Society of Radiologists in Ultrasound: Management of thyroid nodules detected at US: Society of Radiologists in Ultrasound consensus conference statement. Radiology. 2005; 237:794-800
  • Chan BK, Desser TS, McDougall IR, Weigel RJ, Jeffrey RB Jr (2003) Common and uncommon sonographic features of papillary thyroid carcinoma. J Ultrasound Med 22:1083-90
  • Iannuccilli JD, Cronan JJ, Monchik JM. Risk for malignancy of thyroid nodules as assessed by sonographic criteria: the need for biopsy. J Ultrasound Med 2004; 23:1455-64
  • Papini E, Guglielmi R, Bianchini A. Risk of malignancy in nonpalpable thyroid nodules: predictive value of ultrasound and color-Doppler features. J Clin Endocrinol Metab 2002; 87:1941-6.
  • Corrias A, Einaudi S, Chiorboli E. Accuracy of fine needle aspiration biopsy of thyroid nodules in detecting malignancy in childhood: comparison with conventional clinical, laboratory, and imaging approaches. J Clin Endocrinol Metab 2001; 86:4644-8
  • Kwak JY, Han KH, Yoon JH, Moon HJ, Son EJ, Park SH et al. Thyroid imaging reporting and data system for US features of nodules: a step in establishing better stratification of cancer risk. Radiology 2011; 260:892–9.
  • Salmaslioglu A, Erbil Y, Dural C, Issever H, Kapran Y, Ozarmagan S et al. Predictive value of sonographic features in preoperative evaluation of malignant thyroid nodules in a multinodular goiter. World J Surg 2008; 32:1948–54.
  • Gul K, Ersoy R, Dirikoc A, Korukluoglu B, Ersoy PE, Aydin R et al. Ultrasonographic evaluation of thyroid nodules: comparison histopathological findings. Endocrine 2009; 36:464–72.
  • Frates MC, Benson CB, Doubilet PM, Kunreuther E, Contreras M, Cibas ES et al. Prevalence and distribution of carcinoma in patients with solitary and multiple thyroid nodules on sonography. J Clin Endocrinol Metab 2006: 91:3411-7 cytological, and
  • Nam-Goong IS, Kim HY, Gong G, Lee HK, Hong SJ, Kim WB et al. Ultrasonography-guided fineneedle aspiration of thyroid incidentaloma: correlation with pathological findings. Clin Endocrinol 2004: 60:21–8
  • Henrichsen TL, Reading CC, Charboneau JW, Donovan DJ, Sebo TJ, Hay ID. Cystic change in thyroid carcinoma: prevalence and estimated volume in 360 carcinomas. J Clin Ultrasound 2010; 38:361–6
  • Gharib H, Goellner JR. Fine-needle aspiration biopsy of the thyroid: Ann Intern Med. 1993; 118:282-9
  • Hamberger B, Gharib H, Melton LJ 3rd, Goellner JR, Zinsmeister AR. Fine-needle aspiration biopsy of thyroid nodules: impact on thyroid practice and cost of care. Am J Med 1982; 73:381-4
  • Danese D, Sciacchitano S, Farsetti A, Andreoli M, Pontecorvi A. Diagnostic accuracy of conventional versus sonography- guided fine-needle aspiration biopsy of thyroid nodules. Thyroid 1998; 8:15–21.
  • Carmeci C, Jeffrey RB, McDougall IR, Nowels KW, Weigel RJ. Ultrasound-guided fine-needle aspiration biopsy of thyroid masses. Thyroid 1998; 8:283–9.
  • Stangierski A, Wolinski K, Martin K, Leitgeber O, RuchalaM. Core needle biopsy of thyroid nodules - evaluation of diagnostic utility and pain experience. Neuro Endocrinol Lett 2013; 34:798–801
  • Nasrollah N, Trimboli P, Rossi F et al. Patient’s comfort with and tolerability of thyroid core needle biopsy. Endocrine 2013; 45:79–83
  • Papini E, Guglielmi R, Bianchini A, Crescenzi A, Taccogna S, Nardi F et al. CM. Risk of malignancy in nonpalpable thyroid nodules: predictive value of ultrasound and color Doppler features. J Clin Endocrinol Metab 2002; 87:1941-6
  • Kuma K, Matsuzuka F, Yokozawa T, Miyauchi A, Sugawara M. Fate of untreated benign thyroid nodules: results of long- term follow-up. World J Surg. 1994; 18:495-8
  • Rumack CM, Wilson SR, Charboneau JW. Diagnostic Ultrasound Third edition. Mosby 2005 (1):736-43.
There are 25 citations in total.

Details

Primary Language English
Journal Section Research Article
Authors

Çağlayan Çakır This is me

Publication Date September 1, 2019
Published in Issue Year 2019 Volume: 8 Issue: 3

Cite

APA Çakır, Ç. (2019). A comparison of the histopathological results of thyroid nodule biopsy applied with ultrasound-guided traditional technique fine needle aspiration and a novel dual-injector model fine needle aspiration. Abant Medical Journal, 8(3), 147-154. https://doi.org/10.5505/abantmedj.2019.76258
AMA Çakır Ç. A comparison of the histopathological results of thyroid nodule biopsy applied with ultrasound-guided traditional technique fine needle aspiration and a novel dual-injector model fine needle aspiration. Abant Med J. September 2019;8(3):147-154. doi:10.5505/abantmedj.2019.76258
Chicago Çakır, Çağlayan. “A Comparison of the Histopathological Results of Thyroid Nodule Biopsy Applied With Ultrasound-Guided Traditional Technique Fine Needle Aspiration and a Novel Dual-Injector Model Fine Needle Aspiration”. Abant Medical Journal 8, no. 3 (September 2019): 147-54. https://doi.org/10.5505/abantmedj.2019.76258.
EndNote Çakır Ç (September 1, 2019) A comparison of the histopathological results of thyroid nodule biopsy applied with ultrasound-guided traditional technique fine needle aspiration and a novel dual-injector model fine needle aspiration. Abant Medical Journal 8 3 147–154.
IEEE Ç. Çakır, “A comparison of the histopathological results of thyroid nodule biopsy applied with ultrasound-guided traditional technique fine needle aspiration and a novel dual-injector model fine needle aspiration”, Abant Med J, vol. 8, no. 3, pp. 147–154, 2019, doi: 10.5505/abantmedj.2019.76258.
ISNAD Çakır, Çağlayan. “A Comparison of the Histopathological Results of Thyroid Nodule Biopsy Applied With Ultrasound-Guided Traditional Technique Fine Needle Aspiration and a Novel Dual-Injector Model Fine Needle Aspiration”. Abant Medical Journal 8/3 (September 2019), 147-154. https://doi.org/10.5505/abantmedj.2019.76258.
JAMA Çakır Ç. A comparison of the histopathological results of thyroid nodule biopsy applied with ultrasound-guided traditional technique fine needle aspiration and a novel dual-injector model fine needle aspiration. Abant Med J. 2019;8:147–154.
MLA Çakır, Çağlayan. “A Comparison of the Histopathological Results of Thyroid Nodule Biopsy Applied With Ultrasound-Guided Traditional Technique Fine Needle Aspiration and a Novel Dual-Injector Model Fine Needle Aspiration”. Abant Medical Journal, vol. 8, no. 3, 2019, pp. 147-54, doi:10.5505/abantmedj.2019.76258.
Vancouver Çakır Ç. A comparison of the histopathological results of thyroid nodule biopsy applied with ultrasound-guided traditional technique fine needle aspiration and a novel dual-injector model fine needle aspiration. Abant Med J. 2019;8(3):147-54.