The Relationship Between Polypharmacy and Sleep Quality in Patients Admitted to University Hospital

Year 2025, Volume: 14 Issue: 2, 65 - 72, 29.08.2025

Elif Gülnaz Ozcelik , Mertcan Özuysal , Abdurrahim Boran , Nurcan Akbaş Güneş

https://doi.org/10.47493/abantmedj.1665053

Abstract

Abstract
Objective: Polypharmacy, particularly among the elderly, is becoming an increasingly common public health issue. We aimed to evaluate the effects of polypharmacy on sleep quality in individuals aged 40-65.
Materials and Methods: The study was conducted with 461 participants admitted to XXX Training and Research Hospital. After obtaining the necessary consent, the Sociodemographic Form and the Pittsburgh Sleep Quality Index (PSI) were administered to all participants.
Results: The mean age of the participants was 53.95±6.91 years. Of the patients, 49.2% (n=227) were female and 50.8% (n=234) were male. The average PSI score was 6.50±4.42 in patients with polypharmacy and 5.75±3.46 in those without. Poor sleep quality was detected in 55.3% of the participants. There were statistically significant differences between patients with and without polypharmacy in subjective sleep quality, sleep latency, sleep hours, and the use of sleep medications (p=0.023, p=0.000, p=0.033, p=0.006).
Conclusion: Our study found that polypharmacy negatively affects subjective sleep quality, sleep latency, sleep hours, use of sleep medications, and overall sleep quality. It was observed that patients with polypharmacy generally had lower sleep quality and were more likely to use sleep medications. Additionally, patients with hyperpolypharmacy were found to have even lower sleep quality.

Keywords

Polypharmacy , Hyperpolypharmacy , Sleep Quality , Sleep Latency

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