Effects of Clinoptilolite on the Digestibility of Nutrients and Relative Organ Weights in Rat Diets

Year 2018, Volume: 24 Issue: 3, 297 - 302, 05.09.2018

Ramazan Demirel Murat Sedat Baran Dilek Şentürk Demirel Aydın Ketani Beran Yokuş

https://doi.org/10.15832/ankutbd.451270

Cited By: 1

Abstract

This study was conducted to compare the effects of dietary clinoptilolite on nutrient digestibility and relative organ

weights in rats. In this study, 24 adult male Sprague-Dawley rats were divided into 4 groups with 3 replicates, according

to a randomized split plots design. In addition to a control group (0% clinoptilolit), 3 levels of clinoptilolite (2%, 4%, and

6%) were used in the diets, and the rats were fed (individually in cages) these diets for 56 days. Statistically significant

differences were found among the groups for the digestibility rates of nutrients (P<0.05), except for crude fibre (CF) and

acid detergent fibre (ADF). The addition of clinoptilolite in rats’ feeds reduced the digestibility of crude fibre, crude ash

(CA), neutral detergent fibre (NDF) and acid detergent fibre (ADF), but increased the digestibility of other nutrients.

Slaughter live, organs (liver, kidney, heart, and stomach) and relative organ weights were not affected significantly by the

clinoptilolite contents (P>0.05). In conclusion, clinoptilolites can be used in animal feed as natural toxin binders when

stored under suitable conditions.

Keywords

Clinoptilolite; Feed; Nutrient digestibitiy; Relative organ weight; Rat

References

• Abbès S, Salah-Abbès J B, Nahdi K, Younes R B, Hetta M M, El-Kady A A, Abdel-Wahhab M A& Queslati R (2007). Inactivation of cadmium induced immunotoxicological alterations in rats by Tunisian montmorillonite clay. International Immunopharmacology 7: 750-760
• Abdel-Wahhab M A, Nada S A & Amra H A (1999).Effect of aluminosilicates and bentonite on aflatoxininduced developmental toxicity in rat. Journal of Applied Toxicology 19: 199-204
• Adama T Z, Ogunbajo S A & Mambo M (2007). Feed intake, growth performance and nutrient digestibility of broiler chicks fed diets containing varying levels of sorghum dried brewers’ grains. International Journal of Poultry Science 6: 592-598
• Afriyie-Gyawu E, Mackie J, Bhagirathi D, Wiles M, Taylor J, Huebner H, Tang L, Guan H, Wang J S &Phillips T (2005). Chronic toxicological evaluation of dietary Novasil clay in Sprague-Dawley rats. Food Additives and Contamination 22: 259-269
• Ahlstrom O & Skrede A (1998). Comparative nutrient digestibility in dogs, blue fox, mink and rats. American Society for Nutritional Sciences. Journal of Nutrition 128: 2676-2677
• Anonymous (2012). “Rotamin” Feed Additive. Rota Mineral Corporation. http:// www. zeoliteproducer.com /rotamintr.html (Accessed: 11 January 2012)
• AOAC (2000). Official Methods of Analysis. 17th Edition,The Association of Official Analytical Chemists,Gaithersburg, MD, USA
• Baran M S & Kutay H C (1999). Zeolitin hayvan beslemede yem katkısı olarak kullanılması. Hayvancılık Dünyası Dergisi 3(25): 15-19
• Baran M S, Demirel R, Yokuş B & Kocabağlı N (2008). The effect of sorghum grain on live weight gain, feed conversion ratios and digestibility of nutrients in beef cattle. Journal of Animal Veterinary Advance 7: 1123-1127
• Baran M S, Altaçli S, Kaplan O & Deniz S (2017). The determination of nutrient value, digestibility and energy levels of mixed feeds used for ruminant nutrition by in vitro methods. Turkish Journal of Agriculture-Food Science and Technology 5(7): 832- 835
• Crampton E W & Maynard L A (1938). The relation of cellulose and lignin content to nutritive value of animal feeds. Journal of Nutrition 15: 383-395
• Demirel R, Yokuş B, Şentürk D, Ketani M A & Baran M S (2011). Effects of dietary zeolite on serum contents and feeding performance in rats. International Journal of Agriculture and Biology 3: 149-150
• Dschaak C M, Eun J S, Young A J, Stott R D & Peterson S (2010). Effects of supplementation of natural zeolite on intake, digestion, ruminal fermentation, and lactational performance of dairy cows. Professional Animal Science 26: 647-654
• Duncan D B (1995). Multiple Range and Multiple F-Tests.Biometrics, 11, pp. 1-42
• Eleroğlu H & Yalçın H (2012). Dietary effects of Ca-Zeolite supplementation on water consumption and carcass caracteristics of broilers. Journal of Animal Veterinary Advance 11: 43-51
• Eraslan G, Eşsiz D, Akdoğan M, Şahindokuyucu F & Altıntaş L (2005). The effects of aflatoxin and sodium bentonit combined and alone on some blood electrolyte levels in broiler chickens. Turkish Journal of Veterinary and Animal Science 29: 601-605
• Eser H, Yalçın S, Yalçın S & Şehu A (2012). Effects of sepiolite usage in broiler diets on performance,Effects of Clinoptilolite on the Digestibility of Nutrients and Relative Organ Weights in Rat Diets,
• Fokas P, Zervas G, Fegeros K & Zoiopoulos P (2004). Assessment of Pb retention coefficient and nutrient utilization in growing pigs fed diets with added clinoptilolite. Animal Feed Science and Technology 117: 121-129
• Husted W T, Mehen S, Hale W H, Little M & Theurer B (1968). Digestibility of milo processed by different methods. Journal of Animal Science 27: 531-534
• Johnson M A, Sweeney T F & Muller L D (1988). Effects of feeding synthetic zeolite a and sodium bicarbonate on milk production nutrient digestion and rate of digesta passage in dairy cows. Journal of Dairy Science 71: 946-953
• Larsen B Y T, Ostergard K, Hensen I, Knudsen K E &Eggum B O (1991). Daily food intake and digestibiliy in rats. British Journal of Nutrition 65: 29-35
• Martin-Kleiner I, Flegar-Meštrić Z, Zadro R, Breljak D, Janda S S, Stojković R, Marušić M, Radačić M & Boranić M (2001). The effect of the zeolite clinoptilolite on serum chemistry and hematopoiesis in mice. Food Chemical Toxicology 39: 717-727
• National Research Council (1995). Nutrient Requirements of Laboratory Animals, Fourth Revised Edition. National Academy Press, Washington, DC
• Sarı M & Çerçi I H (1993). Feeds, animal nutrition and nutrition diseases, Journal of Fırat University Faculty of Veterinary Medicine, pp. 39-40
• SPSS (1999). Statistical Package for the Social Sciences,Release 10.0. SPSS Inc. Illinois, Chicago, USA
• Sweeney T F, Bull L S & Hemken R W (1980). Effect of zeolite as a feed additive on growth performance in ruminants. Journal of Animal Science 51: 401-409
• Şehu A, Çakır S, Eşsiz D & Ergün L (2005). Preventive effects of HSCAS (Improved milbond-TX®) on aflatoxicosis symptoms in quails. National Animal Nutrition Congress III, September 7-10, Adana, pp. 130-135
• Tang Z G, Chen G Y, Li L F, Wen C, Wang T & Zhou Y M (2015). Effect of zinc-bearing zeolite clinoptilolite on growth performance, zinc accumulation, and gene expression of zinc transporters in broilers. Journal of Animal Science 93(2): 620-626
• Van Soest P J (1987). Nutritional ecology of the ruminant. Second edition. Comstock Publishing Associates,Cornell University Press, Ithaca and London