Case Report

Diagnosis of white muscle disease in two goat kids: combining pathological evaluation with ICP-MS based trace element analysis

Volume: 72 Number: 4 October 1, 2025
EN

Diagnosis of white muscle disease in two goat kids: combining pathological evaluation with ICP-MS based trace element analysis

Abstract

White muscle disease, commonly observed in young ruminants, is a myopathy caused by selenium (Se)/vitamin E deficiency. In this case, white muscle disease was diagnosed in two goat kids following multiple kid mortalities in a hair goat herd in the Gördes district of Manisa province. The disease was diagnosed based on the farmer’s anamnesis, detailed pathological examination, and measurement of Se concentrations in blood and tissue samples using Inductively Coupled Plasma Mass Spectrometry (ICP-MS). In addition to the clinical and pathological findings, the diagnosis of white muscle disease was further supported by the detection of markedly low Se concentrations in the blood, liver, and muscle tissues of the kids. This case report highlights the importance of trace element analysis in the differential diagnosis of white muscle disease from other myopathies in small ruminants.

Keywords

References

  1. Anderson P (1983): Selenium Deficiency in Farm Livestock in Britain. Cambridge University Press, Cambridge.
  2. Beytut E, Karataş F, Beytut E (2002): Lambs with white muscle disease and selenium content of soil and meadow hay in the region of Kars. Vet J, 163, 214-217.
  3. Cooper BJ, Valentine BA (2016): Muscle and tendon. 214-218. In: Maxie MG (Ed), Jubb, Kennedy and Palmer’s Pathology of Domestic Animals. Vol 1, Elsevier, China.
  4. Değer Y, Mert H, Mert N, et al (2008): Serum selenium, vitamin E, and sialic acids concentrations in lambs with white muscle disease. Biol Trace Elem Res, 121, 39-43.
  5. Helmer C, Hannemann R, Humann-Ziehank E, et al (2021): A case of concurrent molybdenosis, secondary copper, cobalt and selenium deficiency in a small sheep herd in northern Germany. Animals, 11, 1864.
  6. Hosnedlová B, Kępińska M, Skalická S, et al (2017): A summary of new findings on the biological effects of selenium in selected animal species—a critical review. Int J Mol Sci, 18, 2209.
  7. Irak K, Mert H, Mert N, et al (2021): Evaluation of various biochemical parameters in the serum and tissues of lambs with white muscle disease. Indian J Anim Res, 55, 1293-1297.
  8. Milli UH, Hazıroğlu R (2000): Veteriner Patoloji. Özkan Matbaacılık, Ankara.

Details

Primary Language

English

Subjects

Veterinary Biochemistry, Veterinary Pathology, Veterinary Diagnosis and Diagnostics

Journal Section

Case Report

Early Pub Date

August 6, 2025

Publication Date

October 1, 2025

Submission Date

April 14, 2025

Acceptance Date

July 19, 2025

Published in Issue

Year 2025 Volume: 72 Number: 4

APA
Okulmuş, Ç., Güner, E., Karaboğa, M., & Turan, D. (2025). Diagnosis of white muscle disease in two goat kids: combining pathological evaluation with ICP-MS based trace element analysis. Ankara Üniversitesi Veteriner Fakültesi Dergisi, 72(4), 537-541. https://doi.org/10.33988/auvfd.1674715
AMA
1.Okulmuş Ç, Güner E, Karaboğa M, Turan D. Diagnosis of white muscle disease in two goat kids: combining pathological evaluation with ICP-MS based trace element analysis. Ankara Univ Vet Fak Derg. 2025;72(4):537-541. doi:10.33988/auvfd.1674715
Chicago
Okulmuş, Çağlar, Erdinç Güner, Mehmet Karaboğa, and Deniz Turan. 2025. “Diagnosis of White Muscle Disease in Two Goat Kids: Combining Pathological Evaluation With ICP-MS Based Trace Element Analysis”. Ankara Üniversitesi Veteriner Fakültesi Dergisi 72 (4): 537-41. https://doi.org/10.33988/auvfd.1674715.
EndNote
Okulmuş Ç, Güner E, Karaboğa M, Turan D (October 1, 2025) Diagnosis of white muscle disease in two goat kids: combining pathological evaluation with ICP-MS based trace element analysis. Ankara Üniversitesi Veteriner Fakültesi Dergisi 72 4 537–541.
IEEE
[1]Ç. Okulmuş, E. Güner, M. Karaboğa, and D. Turan, “Diagnosis of white muscle disease in two goat kids: combining pathological evaluation with ICP-MS based trace element analysis”, Ankara Univ Vet Fak Derg, vol. 72, no. 4, pp. 537–541, Oct. 2025, doi: 10.33988/auvfd.1674715.
ISNAD
Okulmuş, Çağlar - Güner, Erdinç - Karaboğa, Mehmet - Turan, Deniz. “Diagnosis of White Muscle Disease in Two Goat Kids: Combining Pathological Evaluation With ICP-MS Based Trace Element Analysis”. Ankara Üniversitesi Veteriner Fakültesi Dergisi 72/4 (October 1, 2025): 537-541. https://doi.org/10.33988/auvfd.1674715.
JAMA
1.Okulmuş Ç, Güner E, Karaboğa M, Turan D. Diagnosis of white muscle disease in two goat kids: combining pathological evaluation with ICP-MS based trace element analysis. Ankara Univ Vet Fak Derg. 2025;72:537–541.
MLA
Okulmuş, Çağlar, et al. “Diagnosis of White Muscle Disease in Two Goat Kids: Combining Pathological Evaluation With ICP-MS Based Trace Element Analysis”. Ankara Üniversitesi Veteriner Fakültesi Dergisi, vol. 72, no. 4, Oct. 2025, pp. 537-41, doi:10.33988/auvfd.1674715.
Vancouver
1.Çağlar Okulmuş, Erdinç Güner, Mehmet Karaboğa, Deniz Turan. Diagnosis of white muscle disease in two goat kids: combining pathological evaluation with ICP-MS based trace element analysis. Ankara Univ Vet Fak Derg. 2025 Oct. 1;72(4):537-41. doi:10.33988/auvfd.1674715