Investigation of enrofloxacin and ciprofloxacin residues by LC-MS/MS in chicken liver marketed in Afyonkarahisar

Abstract

Antibiotic residues can remain in animal source foods, mainly in the liver. Enrofloxacin (ENR) is a synthetic fluoroquinolone antimicrobial agent which is extensively used to treat bacterial infections in poultry. This study aimed to evaluate ENR and its main metabolite ciprofloxacin (CIP) occurrence in 100 chicken livers marketed Afyonkarahisar, Turkey. Chicken liver samples were analyzed by LC-MS/MS method with limits of detection for 1.17 μg/kg (ENR) and 1.24 μg/kg (CIP). ENR and CIP were detected in 39% and in 31% of samples, respectively. However, the total sum of both antibiotic residue levels was found to be far below the established maximum residue level (200 μg/kg) in all of chicken liver samples. In conclusion, according to the results of this study, chicken livers marketed in Afyonkarahisar city are safe for public health regarding ENR and CIP residues. Nonetheless, periodical control of chicken liver is advised due to the high incidence of these antibiotics.

Keywords

• Antibiotic residue,chicken liver,ciprofloxacin,enrofloxacin,LC-MS/MS

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