Depression Levels and Associated Factors in Individuals with Hereditary Neuromuscular Disease

Abstract

Objective: The purpose of this study was to determine depression and anxiety levels in individuals diagnosed with Hereditary Neuromuscular Diseases (HNMDs) with differing degrees of ambulation, and the factors affecting those levels. Materials and Methods: The study population in this descriptive study consisted of patients under follow-up with diagnoses of HNMD at the Gazi Yaşargil Education and Research Hospital muscular diseases clinic. One hundred fifty-nine patients with varying degrees of ambulation were included. The study data were collected using a sociodemographic data form, the Beck Depression Inventory (BDI), the Beck Anxiety Inventory (BAI), and the Functional Ambulation Classification (FAC). Results: The participants’ mean age was 21.03 ± 9.35 years, and 55.3% were male. Physical ambulation levels were nonfunctional in 24.5% of participants, dependent on supervision in 15.7%, and independent in 59.7%. A significant part of the participants had moderate or severe anxiety levels. The general BAI score was 20.44±10.25, and the general BDI score was 21.03±9.35. Mild and severe depressive symptoms were present in 76.1% of the participants. Advanced age (p<0.05) and high physical dependence levels (p<0.05) emerged as significant variables adversely affecting depression and anxiety levels. Conclusion: It was concluded that especially advanced age and dependent physical ambulation level are important risk factors.

Keywords

• Anxiety
• Depression
• Neuromuscular Disease

Supporting Institution

No support was received from any institution for the project.

Genetik Geçişli Nöromüsküler Hastalığı Olan Bireylerin Depresyon Düzeyi ve İlişkili Faktörler

Abstract

Amaç: Bu çalışmanın amacı, farklı ambulasyon düzeylerine sahip Genetik Geçişli Nöromüsküler Hastalığı (GNMH) olan bireylerin depresyon ve anksiyete düzeyinin belirlenmesi ve etkileyen faktörlerin tespit edilmesidir. Gereç ve Yöntem: Tanımlayıcı olarak tasarlanan çalışmanın evrenini Gazi Yaşargil Eğitim Araştırma Hastanesi Kas Hasatlıkları kliniğinde GNMH tanısı ile takip edilen hastalar oluşturmaktadır. Farklı ambulasyon seviyelerindeki 159 hastanın dahil edildiği çalışmanın verileri sosyodemografik veri formu, Beck Depresyon ölçeği (BDÖ), Beck Anksiyete ölçeği (BAÖ) ve Fiziksel Ambulasyon Skalası (FAS) aracılığı ile toplanmıştır. Bulgular: Çalışmaya katılanların yaş ortalaması 21.03 ± 9.35 ve %55.3’ü erkektir. Katılımcıların %24.5’i fonksiyonel olmayan, %15.7’si gözetimli bağımlı, %59.7’si tam bağımsız seviyesinde fiziksel ambulasyon düzeyine sahiptir. Çalışmaya katılanların önemli bölümü orta ve şiddetli düzeyde anksiyete seviyesine sahip olup, genel BAÖ puan ortalaması 20.44±10.25’ tir. Katılımcıların BDÖ genel puan ortalaması 21.03±9.35’tir. Hafif ve ileri düzey depresyon belirtisi gösterenlerin oranı ise %76.1’dir. GHMH tanılı bireylerde ileri yaş (p<0.05) ve fiziksel bağımlılık düzeyinin yüksek olması (p<0.05) depresyon ve anksiyete düzeyini olumsuz etkileyen önemli değişkenler olarak tespit edilmiştir. Sonuç: Özellikle ileri yaş ve bağımlı fiziksel ambulasyon seviyesinin önemli birer risk faktörü olduğu sonucuna ulaşılmıştır.

Keywords

• Anxiety
• Depression
• Neuromuscular Disease

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