Yüksek Doz Kemoterapi Alan Hastaların Yaşadıkları Semptomların Değerlendirilmesi

Year 2026, Volume: 15 Issue: 1 , 145 - 154 , 28.02.2026

Seher Çakmak , Nesrin Nural

https://doi.org/10.53424/balikesirsbd.1739967

https://izlik.org/JA32JC29GT

Abstract

Amaç: Bu çalışmanın amacı, yüksek doz kemoterapi alan hematolojik kanser hastalarının yaşadıkları semptomları belirlemektir. Gereç ve Yöntem: Tanımlayıcı kesitsel tasarımdaki bu çalışma, bir üniversite hastanesinin hematoloji kliniğinde tedavi gören 158 hasta ile gerçekleştirilmiştir. Veriler kişisel bilgi formu ve “Edmonton Semptom Tanılama Ölçeği” kullanılarak toplanmıştır. Bulgular: Araştırmaya dâhil edilen hastaların yaş ortalaması 45.37±13.24 ve %51.9'u kadındır. Hastaların sırasıyla en fazla yorgunluk (%76.6), iştahsızlık (%66.5), ağrı (%48.7) ve üzüntü (%48.7) semptomlarını yaşadığı belirlenmiştir. Özellikle, birçok semptomun birinci hafta puan ortalamalarının (ağrı, yorgunluk, bulantı, uykusuzluk, iştahsızlık, kendini iyi hissetme durumu, nefes darlığı, ciltte ve tırnaklarda değişiklik, stomatit veya ağız yarası), tedavi öncesine ve/veya ikinci haftaya göre anlamlı derecede daha yüksek olduğu bulunmuştur (p<0.05). Sonuç: Sonuç olarak, yüksek doz kemoterapi alan hastalarda en sık yorgunluk, iştahsızlık, ağrı ve üzüntü semptomları görülmüş ve birçok semptomun şiddeti özellikle birinci haftada artmıştır. Bu bulgular doğrultusunda, hemşirelerin tedavinin erken döneminde semptomları yakından değerlendirmesi, proaktif semptom yönetimi stratejileri uygulaması ve bireyselleştirilmiş bakım planları geliştirmesi önerilmektedir.

Keywords

Kemoterapi , Hematolojik Malignite , Semptom Değerlendirmesi

Ethical Statement

Kurum: Gümüşhane Üniversitesi Bilimsel Araştırma Etik Kurulu Tarih: 28.02.2023 Onay numarası: E-95674917-108.99-164417

Supporting Institution

Bu çalışma, herhangi bir kişi veya kuruluştan finansal destek almamıştır.

Thanks

Yazarlar, bu çalışmaya katkıda bulunan tüm kişilere içtenlikle teşekkür ederler.

Evaluation of Symptoms Experienced by Patients Receiving High-Dose Chemotherapy

https://izlik.org/JA32JC29GT

Abstract

Objective: The aim of this study is to determine the symptoms experienced by hematological cancer patients receiving high-dose chemotherapy. Materials and Methods: This descriptive cross-sectional study was conducted with 158 patients receiving treatment at the hematology clinic of a university hospital. Data were collected using a personal information form and the “Edmonton Symptom Assessment System”. Results: The mean age of the patients included in the study was 45.37±13.24 years and 51.9% were female. It was determined that the patients experienced fatigue (76.6%), anorexia (66.5%), pain (48.7%) and sadness (48.7%) as the most common symptoms, respectively. In particular, the first week mean scores of many symptoms (pain, fatigue, nausea, insomnia, loss of appetite, feeling of well-being, shortness of breath, changes in skin and nails, stomatite or sore mouth) were found to be significantly higher than those before treatment and/or in the second week (p<0.05). Conclusion: In conclusion, fatigue, anorexia, pain and sadness were the most common symptoms in patients receiving high-dose chemotherapy, and the severity of many symptoms increased especially in the first week. Based on these findings, it is recommended that nurses closely assess symptoms in the early phase of treatment, implement proactive symptom management strategies, and develop individualized care plans.

Keywords

Chemotherapy , Hematologic Malignancy , Symptom Evaluation

Ethical Statement

Institution: Gümüshane University Scientific Research Ethics Committee Date: 28.02.2023 Approval no: E-95674917-108.99-164417

Supporting Institution

This study did not receive any financial support from individuals or organizations.

Thanks

The authors sincerely thank all individuals who contributed to this study.

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