Antimycobacterial activity of some lichen extracts

Yıl 2017, Cilt: 10 Sayı: 1, 65 - 68, 15.04.2017

Nalan Yılmaz Sarıözlü Meral Yılmaz Cankılıç

Öz

The acetone, methanol and chloroform extracts of lichens Cetraria aculeata, Cladonia foliacea, Parmelia sulcata, Pseudevernia furfuracea var. furfuracea, Ramalina farinacea and Tornabea scutellifera were investigated for antimycobacteral properties against Mycobacterium tuberculosis H37Rv strain using Microplate Alamar Blue Assay MABA . All of the lichen extracts showed considerable antimycobacterial effect with minimal inhibitory concentration MIC values ranging from 1250 to 156.25 μg/ml. Among the tested lichens, the chloroform extract of the lichen Pseudevernia furfuracea var. furfuracea exhibited the strongest activity with an MIC value of 156.25 μg/ml

Anahtar Kelimeler

antimycobacterial activity, lichen, lichen extracts, MABA, Mycobacterium tuberculosis

Bazı liken ekstraktlarının antimikobakteriyal aktivitesi

Öz

Cetraria aculeata, Cladonia foliacea, Parmelia sulcata, Pseudevernia furfuracea var. furfuracea, Ramalina farinacea ve Tornabea scutellifera likenlerinin aseton, metanol ve kloroform ekstraktlarının Mycobacterium tuberculosis H37Rv suşuna karşı antimikobakteriyal özellikleri Microplate Alamar Blue Assay MABA kullanılarak incelenmiştir. Liken ekstraktlarının tümü 1250-156.25 μg/ml minimal inhibisyon konsantrasyonu MİK aralığındaki değerler ile önemli ölçüde antimikobakteriyal etki göstermiştir. Test edilen likenler arasında Pseudevernia furfuracea var. furfuracea likeninin kloroform ekstraktı 156.25 μg/ml'lik MİK değeri ile en güçlü aktiviteyi göstermiştir

Anahtar Kelimeler

antimikobakteriyal aktivite, liken, liken ekstraktları, MABA, Mycobacterium tuberculosis

Kaynakça

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