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Mycotoxins as health hazard

Year 2012, Volume: 5 Issue: 3, 123 - 133, 15.12.2012

Abstract

A mycotoxin is a toxic secondary metabolite produced by an organism of the fungus kingdom, including mushrooms, molds, and yeasts. Mycotoxins are non-volatile, relatively low-molecular weight secondary metabolites of certain fungi that are toxic to human beings, plants and animals. The production of toxins depends on the surrounding intrinsic and extrinsic environments and the toxins vary greatly in their severity, depending on the organism infected and its susceptibility, metabolism, and defense mechanisms. Mycotoxicosis is the poisoning by ingestion of mycotoxins through food contaminated by toxigenic fungi. Mycotoxins comprise a structurally diverse and chemically complex group of fungal metabolites and many of which have been implicated as significant health hazards on a world wide scale

References

  • Bayman, P, Baker, J.L. 2006. Ochratoxins: a global perspective. Mycopathologia. 162(3): 215-223.
  • Bennett, J.W., Klich, M. 2003. Mycotoxins. Clinical Microbiology Reviews. 16(3): 497-516.
  • Beyer, M., Klix, M.B., Klink, H., Verreet, J.A. 2006. Quantifying the effects of previous crop, tillage, cultivar and triazole fungicides on the deoxynivalenol content of wheat grain – a review. Journal of Plant Diseases and Protection. 113: 241-246.
  • Bokhari, F.M., Aly, M.M. 2009. Evolution of traditional means of roasting and mycotoxins contaminated coffee beans in Saudi Arabia. Advances in Biological Research. 3(3-4): 71-78.
  • Boonyaratpalin, M., Supamattaya, K., Verakunpiriya, V., Suprasert, D., 2001. Effects of aflotoxin B1 on growth performance, blood components, immune function and histopatological changes in black tiger shrimp (Paneus monodon Fabricius). (suppl. 1). Aquaculture Research. 32: 388-398.
  • Burgos-Hernandez, A., Farias, S.I., Torres-Arreola, W., Ezquerra-Brauer, J.M., 2005. In vitro studies of the effects of aflotoxin B1 and fumonisin B1 on trypsin-like and collagenase-like activity from the hepatopancreas of white shrimp (Litopanaeus vannamei). Aquaculture. 250: 399-410.
  • Christensen, C.M. 1975. Molds, Mushrooms, and Mycotoxins. University of Minnesota Press, Minneapolis. p. 264.
  • Hudler, G. 1998. Magical and Mischievous Molds. Princeton University Press. p. 248.
  • Desjardins, A.E, Proctor, R.H. 2007. Molecular biology of Fusarium mycotoxins. International Journal of Food Microbiology. 119(1-2): 47-50.
  • Dubey, R.C. 2006. A Textbook of Biotechnology. 4th ed., S. Chand, Co, Ram Nagar, New Delhi.
  • Fox, E.M., Howlett, B.J. 2008. Secondary metabolism: regulation and role in fungal biology. Current Opinion in Microbiology. 1 (6): 481-487.
  • Kamei, K., Watanabe, A. 2005. Aspergillus mycotoxins and their effect on the host. Medical Mycology Supplement. 43: 95-99.
  • Manning, B.B., 2001. Mycotoxins in fish feeds. In Nutrition and Fish Health. Lim, C., Webster, C.D. Eds). Food Products Press. New York. p. 365.
  • Martins, M.L., Martins, H.M., Bernardo, F. 2001. Aflatoxins in spices marketed in Portugal. Food Additives and Contaminants. 18(4): 315-319.
  • Mirocha, C.J., Pawlosky, R.A., Chatterjee, K. Watson, S., Hayes, W. 1983. Analysis for Fusarium toxins in various samples implicated in biological warfare in Southeast Asia. Journal Association of Official Analytical Chemists. 66(6): 1485-1499.
  • Moss, M.O. 2008. Fungi, quality and safety issues in fresh fruits and vegetables. Journal of Applied Microbiology. 104(5): 1239- 1243.
  • Richard, J.L. 2007. Some major mycotoxins and their mycotoxicoses-an overview. International Journal of Food Microbiology. 119(1-2): 3-10.
  • Roy, A.K. 1996. Mycotoxins their dimensions and hazards. In: Contemporary Thoughts in Plant Sciences. Ed. P.K. Pal. Academic Staff College, Burdwan University. pp. 219-227.
  • Seefelder, W., Gossmann, M., Humpf, H.V. 2002. Analysis of fumonisin B1 in Fusarium proliferatum infected asparagus spears and garlic bulbs from Germany by liquid chromatography ionization mass spectrometry. Journal of Agricultural and Food Chemistry. 50: 2778-2781.
  • Schaafsma, A.W., Hooker, D.C. 2007. Climatic models to predict occurrence of Fusarium toxins in wheat and maize. International Journal of Food Microbiology. 119(1-2): 116-125.
  • Supamattaya, K., Bundit, O., Boonyarapatlin, M., Schatzmayr, G., 2006. Effects of mycotoxins T-2 and zearalenone on growth performance immuno-ohysiological parameters and histological changes in Black tiger shrimp (Penaeus monodon) and white shrimp (Litopenaeus vannamei). XII International Symposium of Fish Nutrition & Feeding. May 28 - June 1. Biarritz, France.
  • Trigo-Stockli, D.M., Obaldo, L.G., Gominy, W.G., Behnke, K.C., 2000. Utilization of deoxynivalenol-contaminated hard red winter wheat for shrimp feeds. Journal of the World Aquaculture Society. 31: 247-254.
  • Turner, N.W., Subrahmanyam, S., Piletsky, S.A. 2009. Analytical methods for determination of mycotoxins: a review. Analytica Chimica Acta. 632(2): 168-180.
  • Ueno, Y. 1989. Trichothecene mycotoxins: Mycology, chemistry and toxicology. Advances in Nutritional Research. 3: 301-353.
  • Uraguchi, K., Yamazaki, M. 1978. Toxicology Biochemistry and Pathology of Mycotoxins. John Willey and Sons. New York. pp. 2- 12.
  • Watson, S.A., Mirocha, C.J., Hayes, A.W. 1984. Analysis for trichothecenes in samples from Southeast Asia associated with Yellow rain. Fundamental and Applied Toxicology. 4(5): 700-717.

Sağlık açısından bir tehlike olarak mikotosinler

Year 2012, Volume: 5 Issue: 3, 123 - 133, 15.12.2012

Abstract

Bir mikotoksin; mantar, küf ve maya da dahil olmak üzere, mantar aleminden bir organizma tarafından üretilen toksik sekonder metabolitidir. Mikotoksinler, insan, bitki ve hayvanlar için toksik olan belirli mantarların uçucu olmayan, göreceli olarak düşük molekül ağırlıklı ikincil metabolitlerdir. Toksin üretimi iç ve dış ortamlarda bağlıdır ve toksin bulaşmış organizma ve duyarlılık, metabolizma ve savunma mekanizmalarına bağlı olarak, onların şiddeti büyük ölçüde değişir. Mikotoksikoz toksijenik mantarlar tarafından kontamine yiyecek yoluyla mikotoksinler tüketilmesi ile zehirlenmesidir. Mikotoksinler fungal metabolitlerin yapısal olarak farklı ve kimyasal karmaşık bir grup oluşturan ve bir çoğu dünya çapında bir ölçekte önemli sağlık tehlikesi olarak sorumlu tutulmuştur

References

  • Bayman, P, Baker, J.L. 2006. Ochratoxins: a global perspective. Mycopathologia. 162(3): 215-223.
  • Bennett, J.W., Klich, M. 2003. Mycotoxins. Clinical Microbiology Reviews. 16(3): 497-516.
  • Beyer, M., Klix, M.B., Klink, H., Verreet, J.A. 2006. Quantifying the effects of previous crop, tillage, cultivar and triazole fungicides on the deoxynivalenol content of wheat grain – a review. Journal of Plant Diseases and Protection. 113: 241-246.
  • Bokhari, F.M., Aly, M.M. 2009. Evolution of traditional means of roasting and mycotoxins contaminated coffee beans in Saudi Arabia. Advances in Biological Research. 3(3-4): 71-78.
  • Boonyaratpalin, M., Supamattaya, K., Verakunpiriya, V., Suprasert, D., 2001. Effects of aflotoxin B1 on growth performance, blood components, immune function and histopatological changes in black tiger shrimp (Paneus monodon Fabricius). (suppl. 1). Aquaculture Research. 32: 388-398.
  • Burgos-Hernandez, A., Farias, S.I., Torres-Arreola, W., Ezquerra-Brauer, J.M., 2005. In vitro studies of the effects of aflotoxin B1 and fumonisin B1 on trypsin-like and collagenase-like activity from the hepatopancreas of white shrimp (Litopanaeus vannamei). Aquaculture. 250: 399-410.
  • Christensen, C.M. 1975. Molds, Mushrooms, and Mycotoxins. University of Minnesota Press, Minneapolis. p. 264.
  • Hudler, G. 1998. Magical and Mischievous Molds. Princeton University Press. p. 248.
  • Desjardins, A.E, Proctor, R.H. 2007. Molecular biology of Fusarium mycotoxins. International Journal of Food Microbiology. 119(1-2): 47-50.
  • Dubey, R.C. 2006. A Textbook of Biotechnology. 4th ed., S. Chand, Co, Ram Nagar, New Delhi.
  • Fox, E.M., Howlett, B.J. 2008. Secondary metabolism: regulation and role in fungal biology. Current Opinion in Microbiology. 1 (6): 481-487.
  • Kamei, K., Watanabe, A. 2005. Aspergillus mycotoxins and their effect on the host. Medical Mycology Supplement. 43: 95-99.
  • Manning, B.B., 2001. Mycotoxins in fish feeds. In Nutrition and Fish Health. Lim, C., Webster, C.D. Eds). Food Products Press. New York. p. 365.
  • Martins, M.L., Martins, H.M., Bernardo, F. 2001. Aflatoxins in spices marketed in Portugal. Food Additives and Contaminants. 18(4): 315-319.
  • Mirocha, C.J., Pawlosky, R.A., Chatterjee, K. Watson, S., Hayes, W. 1983. Analysis for Fusarium toxins in various samples implicated in biological warfare in Southeast Asia. Journal Association of Official Analytical Chemists. 66(6): 1485-1499.
  • Moss, M.O. 2008. Fungi, quality and safety issues in fresh fruits and vegetables. Journal of Applied Microbiology. 104(5): 1239- 1243.
  • Richard, J.L. 2007. Some major mycotoxins and their mycotoxicoses-an overview. International Journal of Food Microbiology. 119(1-2): 3-10.
  • Roy, A.K. 1996. Mycotoxins their dimensions and hazards. In: Contemporary Thoughts in Plant Sciences. Ed. P.K. Pal. Academic Staff College, Burdwan University. pp. 219-227.
  • Seefelder, W., Gossmann, M., Humpf, H.V. 2002. Analysis of fumonisin B1 in Fusarium proliferatum infected asparagus spears and garlic bulbs from Germany by liquid chromatography ionization mass spectrometry. Journal of Agricultural and Food Chemistry. 50: 2778-2781.
  • Schaafsma, A.W., Hooker, D.C. 2007. Climatic models to predict occurrence of Fusarium toxins in wheat and maize. International Journal of Food Microbiology. 119(1-2): 116-125.
  • Supamattaya, K., Bundit, O., Boonyarapatlin, M., Schatzmayr, G., 2006. Effects of mycotoxins T-2 and zearalenone on growth performance immuno-ohysiological parameters and histological changes in Black tiger shrimp (Penaeus monodon) and white shrimp (Litopenaeus vannamei). XII International Symposium of Fish Nutrition & Feeding. May 28 - June 1. Biarritz, France.
  • Trigo-Stockli, D.M., Obaldo, L.G., Gominy, W.G., Behnke, K.C., 2000. Utilization of deoxynivalenol-contaminated hard red winter wheat for shrimp feeds. Journal of the World Aquaculture Society. 31: 247-254.
  • Turner, N.W., Subrahmanyam, S., Piletsky, S.A. 2009. Analytical methods for determination of mycotoxins: a review. Analytica Chimica Acta. 632(2): 168-180.
  • Ueno, Y. 1989. Trichothecene mycotoxins: Mycology, chemistry and toxicology. Advances in Nutritional Research. 3: 301-353.
  • Uraguchi, K., Yamazaki, M. 1978. Toxicology Biochemistry and Pathology of Mycotoxins. John Willey and Sons. New York. pp. 2- 12.
  • Watson, S.A., Mirocha, C.J., Hayes, A.W. 1984. Analysis for trichothecenes in samples from Southeast Asia associated with Yellow rain. Fundamental and Applied Toxicology. 4(5): 700-717.
There are 26 citations in total.

Details

Primary Language Turkish
Journal Section Research Article
Authors

Selima Khatun This is me

Manoranjan Chakraborty This is me

Aminul Islam This is me

Ugur Cakılcıoglu This is me

Narayan C Chatterjee This is me

Publication Date December 15, 2012
Published in Issue Year 2012 Volume: 5 Issue: 3

Cite

APA Khatun, S., Chakraborty, M., Islam, A., Cakılcıoglu, U., et al. (2012). Sağlık açısından bir tehlike olarak mikotosinler. Biological Diversity and Conservation, 5(3), 123-133.

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