Determination of MIC and MBC Values Using Different Extraction Methods in Plants of Nigella Sativa, Cuminum Cyminum and Pimpinella Anisum L. Samples from Kırıkkale Region

Abstract

In our study, it was aimed to investigate the antimicrobial effect of 6 plant extracts obtained with methanol by using maceration and soxlet methods from 3 plant species Nigellla sativa (Black seed), Cuminum cuminum (cumin) and Pimpinella anisum (anise) grown in Kırıkkale province by liquid microdilution method against Staphylococcus aureus (ATCC 25923) and Escherichia coli (ATCC 25922). All of the extracts of Nigellla sativa (black cumin), Cuminum cuminum (Cuminum) and Pimpinella anisum (Anise) prepared by the maceration and soxalet method showed antibacterial effects against both bacteria (inhibitory and bactericidal). it was determined that the antibacterial effect of the extracts obtained by the maceration method was higher than the extracts obtained by the soxalet method.

Keywords

• MIC
• MBC
• METHANOL

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