The Combined Use of SCD Probiotics and Tauroursodeoksikolik Asit (TUDCA) is More Effective in Controlling Anxiety-Like Behavior in Aged Rats

Yıl 2023, Cilt: 12 Sayı: 1, 242 - 246, 22.03.2023

Taha Ceylani , Hikmet Taner Teker

https://doi.org/10.17798/bitlisfen.1231238

Öz

In this study, the effects of TUDCA administration with a SCD probiotics for one week on locomotors activity and anxious behavior were investigated. Male Saprague-Dawley rats aged 24 months were used as the model organism. At the end of the application, open-field and elevated plus maze behavioral tests were performed on the rats. Although SCD probiotics were more effective on anxious behavior, the group in which they were administered together had a significantly greater effect on locomotor activity and anxious behavior. This study provides important evidence that combining SCD probiotics and TUDCA administration may be more beneficial to behavior.

Anahtar Kelimeler

TUDCA, SCD probiotics, OF, EPM, Anxiety.

Kaynakça

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