Research Article

Cancer Modeling by Fractional Derivative Equation and Chemotherapy Stabilizing

Volume: 7 Number: 3 September 29, 2024
EN

Cancer Modeling by Fractional Derivative Equation and Chemotherapy Stabilizing

Abstract

This paper discusses the theme of cancer modeling and the control problem of chemotherapy. Cancer spread is modeled by fractional derivative equation and asymptotically stabilized by chemotherapy law. The model is converted by fractional complex transform into a simple partial derivative equation and associated with a viability problem, and the set-valued analysis is used to make the converted model viable by the regulation law of the regulation map. The regulation law is used to give the stabilizing chemotherapy control for a specific model of the glioblastomas multiforme (GBM) tumor concentration.

Keywords

Chemotherapy, Fractional derivative equation, Viability theory

References

  1. [1] T. Alinei-Poiana, E. Dulf, L. Kovacs, Fractional calculus in mathematical oncology, Sci. Rep., 13 (2023), 10083.
  2. [2] N. Sweilam, M. Khader, A. Mahdy, Numerical studies for solving fractional-order logistic equation, Int. J. Pure Appl. Math., 78 (2012), 1199-1210.
  3. [3] N. Djeddi, S. Hasan, M. Al-Smadi, S. Momani, Modified analytical approach for generalized quadratic and cubic logistic models with Caputo-Fabrizio fractional derivative, Alex. Eng. J., 59 (2020), 5111-5122.
  4. [4] A. Kanth, N. Garg, Computational simulations for solving a class of fractional models via Caputo-Fabrizio fractional derivative, Procedia Comput. Sci., 125 (2018), 476-482.
  5. [5] S. Arshad, I. Saleem, A. Akg¨ul, J. Huang, Y. Tang, S. Eldin, A novel numerical method for solving the Caputo-Fabrizio fractional differential equation, AIMS Math., 8 (2023), 9535-9556.
  6. [6] N. Varalta, A. Gomes, R. Camargo, A prelude to the fractional calculus applied to tumor dynamic, TEMA Tend. Mat. Apl. Comput., 15 (2014), 211-221.
  7. [7] F. Ariza-Hernandez, M. Arciga-Alejandre, J. Sanchez-Ortiz, A. Fleitas-Imbert, Bayesian derivative order estimation for a fractional logistic model, Mathematics, 8 (2020), 109.
  8. [8] M. Meabed Khader, M. Babatin, Others on approximate solutions for fractional logistic differential equation, Math. Probl. Eng., 2013 (2013).
  9. [9] S. Khajanchi, M. Sardar, J. Nieto, Application of non-singular kernel in a tumor model with strong Allee effect, Differ. Equ. Dyn. Syst., (2022), 1-6.
  10. [10] S. Debbouche, Implicit solution for logistic Caputo-Fabrizio fractional differential equation with Allee effect, J. Fract. Calc. Nonlinear Syst., 4 (2023), 1-7.
APA
Moustafid, A. (2024). Cancer Modeling by Fractional Derivative Equation and Chemotherapy Stabilizing. Communications in Advanced Mathematical Sciences, 7(3), 125-134. https://doi.org/10.33434/cams.1486049
AMA
1.Moustafid A. Cancer Modeling by Fractional Derivative Equation and Chemotherapy Stabilizing. Communications in Advanced Mathematical Sciences. 2024;7(3):125-134. doi:10.33434/cams.1486049
Chicago
Moustafid, Amine. 2024. “Cancer Modeling by Fractional Derivative Equation and Chemotherapy Stabilizing”. Communications in Advanced Mathematical Sciences 7 (3): 125-34. https://doi.org/10.33434/cams.1486049.
EndNote
Moustafid A (September 1, 2024) Cancer Modeling by Fractional Derivative Equation and Chemotherapy Stabilizing. Communications in Advanced Mathematical Sciences 7 3 125–134.
IEEE
[1]A. Moustafid, “Cancer Modeling by Fractional Derivative Equation and Chemotherapy Stabilizing”, Communications in Advanced Mathematical Sciences, vol. 7, no. 3, pp. 125–134, Sept. 2024, doi: 10.33434/cams.1486049.
ISNAD
Moustafid, Amine. “Cancer Modeling by Fractional Derivative Equation and Chemotherapy Stabilizing”. Communications in Advanced Mathematical Sciences 7/3 (September 1, 2024): 125-134. https://doi.org/10.33434/cams.1486049.
JAMA
1.Moustafid A. Cancer Modeling by Fractional Derivative Equation and Chemotherapy Stabilizing. Communications in Advanced Mathematical Sciences. 2024;7:125–134.
MLA
Moustafid, Amine. “Cancer Modeling by Fractional Derivative Equation and Chemotherapy Stabilizing”. Communications in Advanced Mathematical Sciences, vol. 7, no. 3, Sept. 2024, pp. 125-34, doi:10.33434/cams.1486049.
Vancouver
1.Amine Moustafid. Cancer Modeling by Fractional Derivative Equation and Chemotherapy Stabilizing. Communications in Advanced Mathematical Sciences. 2024 Sep. 1;7(3):125-34. doi:10.33434/cams.1486049