Clinical, Laboratory and Angiographic Features in Young Myocardial Infarct: A multicenter retrospective study

Abstract

Objective: Our aim in this study was to compare the clinical, laboratory and angiographic features of patients under 45 years of age hospitalized with acute coronary syndrome (heart attack with ST-segment elevation and heart attack without ST-segment elevation) with those in the middle-aged group aged 45-65 years. Materials and Methods: The study was planned retrospectively. The files of patients admitted to our clinic with the diagnosis of acute coronary syndrome and undergoing coronary angiography for the first time were scanned. Those aged 45 and under were considered as young heart attacks, while those over 45 and 65 years of age and under were considered as the control group. Results: In univariate logistic regression analysis results, hypertension (odds ratio (OR): 4.367, 95% confidence interval (CI) [2.631-7.248], p<0.001), DM (OR: 3.252, 95% CI [1.952-5.417]), p<0.001), smoking (OR: 0.614, 95% CI [0.405-0.929], p=0.021), serum glucose level (OR:0.995, 95% CI [0.992-0.998], p=0.003) and frontal QRS While the -T angle (OR: 0.995, 95% CI [0.990-0.999], p=0.017) was significant, multivariate regression analysis showed hypertension (OR: 3.403, 95% CI [1.996-5.801], p<0.001) was determined as possible independent risk factors. Conclusion: As a result, hypertension, diabetes and smoking were found to be the leading causes of heart attack in young patients. Young patients with these risk factors should be examined for coronary artery disease and earlier treatments such as statins and acetylsalicylic acid should be considered. In addition, early diagnosis and treatment of risk factors such as DM, HT and smoking in these patients can prevent the development of heart attack in the young patient group.

Keywords

• Young myocardial infarct
• risk factors
• coronary angiography

Genç Kalp Krizlerinde Klinik, Laboratuvar ve Anjiyografi Özellikleri: Çok merkezli retrospektif çalışma

Abstract

Giriş ve Amaç: 45 yaş altında akut koroner sendrom (ST segment yükselmeli kalp krizi ve ST segment yükselmesi olmayan kalp krizi) ile yatırılan hastaların klinik, laboratuvar ve anjiyografi özelliklerini 45-65 yaş arasındaki orta yaş grubundaki hastalarla karşılaştırmak amacı ile bu çalışma planlandı. Gereç ve Yöntemler: Çalışma retrospektif olarak planlamıştır. Akut koroner sendrom tanısı ile yatırılan ve ilk defa koroner anjiyografi yapılan hastaların dosyaları taranmıştır. 45 yaş ve altında olanlar genç kalp krizi olarak kabul edilirken 45 yaş üstü ve 65 yaş ve altı olanlar kontrol grubu olarak kabul edilmiştir. Bulgular: Tek değişkenli lojistik regresyon analiz sonuçlarında, hipertansiyon (odds oranı (OO): 4.367, %95 güven aralığı (GA) [2.631-7.248], p<0.001), DM (OO: 3.252, %95 GA [1.952-5.417], p<0.001), sigara içiciliği (OO: 0.614, %95 GA [0.405-0.929], p=0.021), serum glikoz düzeyi (OO:0.995, %95 GA [0.992-0.998], p=0.003) çok değişkenli regresyon analizlerinde hipertansiyon (OO: 3.403, %95 GA [1.996-5.801], p<0.001) olası bağımsız birer risk faktörü olarak saptandı. Sonuç: Sonuç olarak hipertansiyon, diyabet ve sigara genç hastalarda öne çıkan kalp krizi nedenleri olarak bulunmuştur. Bu risk faktörlerine sahip genç hastalar KAH yönünden tetkik edilmeli ve KAH hastalığı yönünden riskli kabul edilerek statin, asetilsalisik asit gibi tedaviler daha erken başlanması düşünülmelidir. Ayrıca bu hastalar da DM, HT, sigara gibi risk faktörlerinin erken tanısı ve tedavisi ile genç hasta grubunda kalp krizi gelişimi önlenebilir.

Keywords

• genç kalp krizi
• risk faktörleri
• koroner anjiografi

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