Sweet’s syndrome-like dermatosis associated with paracetamol and chlorpheniramine maleate bilaterally localized on breasts

Abstract

Sweet’s syndrome is a reactive process with massive neutrophil infiltration of the dermis. It presents with warm, tender, red papules, nodules and plaques usually occur on the upper extremities, face or neck with typically concomitant fever and peripheral neutrophilia. The Sweet’s syndrome is so often idiopathic, sometimes associated with diseases and drugs rarely. Some of the drug-related cases clinically present like Sweet’s syndrome but partly differ with the type of histologic infiltrate and in some of them with the absence of systemic manifestations. We describe herein an unusual Sweet’s syndrome-like dermatosis case associated with paracetamol and chlorpheniramine maleate localized on breasts.    

Keywords

• Sweet-Like Dermatosis,Breast,Drug,Nonsteroidal Antiinflammatory Agent

Parasetamol ve klorfeniramin maleata bağlı gelişen bilateral meme yerleşimli Sweet sendrom benzeri dermatoz

Abstract

Sweet sendromu dermiste yoğun nötrofil infiltrasyonu ile karakterize reaktif bir proçestir. Ateş ve periferal nötrofili ile birlikte genellikle üst ekstremiteler, yüz veya boyunda lokalize kırmızı renkli, hassas ve ısı artışı gösteren papül, nodül ve plaklar ile seyretmektedir. Sweet sendromu sıklıkla idiyopatik olup bazen hastalıklara eşlik etmekte, nadiren de ilaçlara bağlı gelişmektedir. İlaçla ilişkili bazı olgularda klinik Sweet sendromuna benzese de histolojik infiltratın tipi ve bazılarında da sistemik bulguların olmaması nedeniyle farklılık gösterebilmektedir. Burada meme derisinde lokalize parasetamol ve klorfeniramin maleat ile ilişkili sıradışı bir Sweet benzeri dermatoz olgusu sunulmaktadır.

Keywords

• Sweet Benzeri Dermatoz,Meme,İlaç,Nonsteroidal Antiinflamatuar Ajan

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