Maternal ve Fetal Sağlık İçin Büyük Tehlike: Maternal Obezite

Büşra Demirer; Hülya Yardımcı

doi:10.34087/cbusbed.685203

Maternal ve Fetal Sağlık İçin Büyük Tehlike: Maternal Obezite

Öz

Maternal obezite, dünya çapında prevalansı gittikçe artan patolojik bir durumdur. Maternal, fetal-neonatal sağlığı olumsuz etkilemektedir. Gestasyonel diyabet, hipertansiyon, preeklampsi, düşük riski, enfeksiyonlar en sık karşılaşılan maternal komplikasyonlar iken, preterm doğum, makrozomi, konjenital anomaliler, fetal ve neonatal mortalite en sık karşılaşılan fetal komplikasyonlardandır. Maternal obezite ayrıca erken çocukluk dönemi sorunlarına ve uzun süreli sağlık problemlerine de yol açabilmektedir. Maternal obezitenin neden olduğu komplikasyonlar göz önüne alındığında, tedavi yöntemlerinin geliştirilmesinin önemi ortaya çıkmaktadır. Bu konuda öncelikle gebelik öncesi kadının normal ağırlığına getirilip gebe kalması oldukça önemlidir. Prekonsepsiyonel dönemde kadınlara obezitenin olası sonuçları hakkında bilgilendirme yapılmalıdır. İlk prenatal muayeneden itibaren düzenli ağırlık izlemi yapılmalıdır. Uluslararası otoriteler tarafından belirlenmiş ağırlık kazanım miktarlarına dikkat edilmelidir. Sağlıklı bir gebelik süreci için gerekli taramaların yapılması sağlanmalıdır. İlk muayeneden itibaren bireysel olarak hazırlanmış beslenme ve fiziksel aktivite programlarına uyulmalıdır. Bu derleme çalışmasında günümüzde prevalansı oldukça yüksek olan maternal obezitenin olası maternal ve fetal komplikasyonlarının, emzirme dönemine etkilerinin güncel bilgiler eşliğinde paylaşılması amaçlanmıştır.

Anahtar Kelimeler

maternal,beslenme,fetal,diyabet

Kaynakça

1. Institute of Medicine, (IOM), Weight gain during pregnancy: Reexamining the Guidelines, Report Brief, 2010.
2. American College of Obstetricians and Gynecologists (ACOG), Obesity in pregnancy. ACOG Practice Bulletin No. 156. Obstet Gynecol, 2010, 126, 112-122.
3. Wang, D, Cui, K, Wu, G, Feng, F, Yu, X, Association of prepregnancy BKI, rate of gestational weight gain with pregnancy outcomes Chinese urban women, Nutrition and Metabolism, 2019, 16(1), 54.
4. Melchor, I, Burgos, J, Del, Campo, A, Aiartzaguena, A, Gutiérrez, J, Melchor, J.C, Effect of maternal obesity on pregnancy outcomes in women delivering singleton babies: a historical cohort study, Journal of Perinatal Medicine, 2019, 47(6), 625-630.
5. Okesene-Gafa, K.A.M, Li, M, Mckinlay, C.J.D, Taylor, R.S, Rush, E.C, Wall, C.R et al. Effect of antenatal dietary interventions in maternal obesity on pregnancy weight-gain and birthweight: Healthy Mums and Babies (HUMBA) randomized trial, American Journal of Obstetrics and Gynecology, 2019, 221(2), 152.
6. Hoover, E.A, Louis, J.M, Optimizing Health, Obstetrics and Gynecology Clinics of North America, 2019, 46(3), 431-440.
7. Deputy, N.P, Dub, B, Sharma, A.J, Prevelance and Trends in Prepregnancy Normal Weight-48 States, New York City and District of Columbia, 2011-2015, Weekly, 2018, 66(5152), 1402–1407.
8. Eiriksdottir, V.H, Valdimarsdottir, U.A, Asgeirsdottir, T.L, Gisladottir, A, Lund, S.H, Hauksdottir, A, Smoking and obesity among pregnant women in Iceland, European Journal of Public Health, 2015, 25(4), 638-643.

9. MacInnis, N, Woolcott, C.G, McDonald, S, Kuhle, S, Population Attributable Risk Fractions of Maternal Overweight and Obesity for Adverse Perinatal Outcomes, Scientific Reports, 2016, 6, 22895.
10. Shagana, J.A, Dhanraj, M, Jain, A.R, Nirosa, T, Physiological changes in pregnancy, Drug Invention Today, 2018, 10(8), 1594-1597.
11. Soma-Pillay, P, Nelson-Piercy, C, Tolppanen, H, Mebazaa, A, Physiological changes in pregnancy, Cardiovascular Journal of Africa, 2016, 27(2), 89–94.
12. Munda, A, Starčič, Erjavec, M, Molan, K, Ambrožič, Avguštin, J, Žgur-Bertok, D, Pongrac, Barlovič, D, Association between pre-pregnancy body weight and dietary pattern with large-for-gestational-age infants in gestational Diabetes, Diabetology & Metabolic Syndrome, 2019, 11(1), 68.
13. Taşdemir, D, Karaman, E, Yıldız, A, Han, A, Obezitenin term gebelerde maternal ve fetal sonuçlara etkisi: bir olgu kontrol çalışması, İKSST Dergisi, 2015, 7(2), 73-78.
14. Kim, M.K, Hur, J, Lee, S.Y, Kim, L.Y, Park, K.S, Park, S.W et al. Maternal obesity and associated risk of adverse pregnancy outcomes in women wıth hyperglycemia, Korean J Obstet Gynecol, 2011, 54(10), 591-598.
15. Gürkan, E, Dirican, E, Bülbül, N, Bilinen ve Olası Risk Faktörlerinin Birlikteliğinin Gestasyonel Diabetes Mellitus Gelişimine Etkisi, Ankara Med J, 2018, 3, 382‐90.
16. American Diabetes Association (ADA), Standards of medical care in diabetes-2010, Diabetes Care, 2010, 33, 11-61.
17. Institute of Obstetricians and Gynaecologists (IOM), Obesity and pregnancy clinical practice Guideline 2, 2013.
18. Triebwasser, J.E, Kazzi,,N.G, Davis, M.B, Kobernik, E.K, Levine, L.D, Langen, E.S, Cardiac remodeling in morbidly obese women and its association with adverse perinatal outcomes, Pregnancy Hypertension, 2019, 17, 104–108.
19. Institute of Obstetricians and Gynaecologists, Obesity and pregnancy clinical practice Guideline 3,2016.
20. Frederick, I.O, Rudra, C.B, Miller, R.S, Foster, J.C, Williams, M.A, Adult weight change, weight cycling, and prepregnancy obesity in relation to risk of preeclampsia, Epidemiology, 2008, 17, 428–434.
21. Kerrigan, A, Kingdon, C, Maternal obesity and pregnancy: a retrospective study, Midwifery, 2010, 26(1), 138-46.
22. Thagaard, I.N, Hedley, P.L, Holm, J.C, Lange, T, Larsen, T, Krebs, L et al. Leptin and Adiponectin as markers for preeclampsia in obese pregnant women, a cohort study, Pregnancy Hypertension, 2019, 15, 78–83.
23. İnci, M, İnci, M, Davarcı, M, Gebelikte görülen üriner sistem enfeksiyonları ve tedavisi, Türkiye Üroloji Semineri, 2014, 2, 124-6.
24. McCall, S.J, Li, Z, Kurinczuk, J.J, Sullivan, E, Knight, M, Maternal and perinatal outcomes in pregnant women with BMI >50: An international collaborative study, PLOS ONE, 2019, 14(2), 1-11.
25. Laskewitz, A, Van, Benthem, K.L, Kieffer, T.E.C, Faas, M.M, Verkaik-Schakel, R.N, Plösch, T et al. The influence of maternal obesity on macrophage subsets in the human decidua, Cellular Immunology, 2019, 336, 75-82.
26. Melchor, I, Burgos, J, Del Campo, A, Aiartzaguena, A, Gutiérrez, J, Melchor, J.C, Effect of maternal obesity on pregnancy outcomes in women delivering singleton babies: a historical cohort study, J. Perinat. Med, 2019, 47(6), 625–630.
27. Sagi, Y, Snelgrove, J, Vernon, J, D’Souza, R, Maxwell, C, Wound Disruption Following Caesarean Delivery in Women With Class III Obesity: A Retrospective Observational Study, Journal of Obstetrics and Gynaecology Canada, 2019, 41(6), 798-804.
28. Haile, Z.T, Chavan, B, Teweldeberhan, A.K, Chertok, I.R.A, Francescon, J, Gestational weight gain and unplanned or emergency cesarean delivery in the United States, Women and Birth, 2019, 32(3), 263-269.
29. American College of Obstetricians and Gynecologists (ACOG), Obesity in pregnancy practice bulletin 156, Obstet Gynecol, 2015, 126, 112- 122.
30. Sirimi, N, Goilis, G.D, Obesity in pregnancy, Aristotle University of Thessaloniki, Greece, Hormones, 2010, 9(4), 299-306.
31. Persson, M, Razaz, N, Edstedt Bonamy, A.K, Villamor, E, Cnattingius, S, Maternal Overweight and Obesity and Risk of Congenital Heart Defects, Journal of the American College of Cardiology, 2019, 73(1), 44–53.
32. O’Malley, E, Reynolds, C, Cawley, S, Woodside, J.V, Molloy, A.M, Turner, M.J, Folate and vitamin B12 levels in early pregnancy and maternal obesity, European Journal of Obstetrics & Gynecology and Reproductive Biology, 2018, 231, 80-84.
33. Zhang, L, Zhang, Y, Li, Z, Ren, A, Liu, J, Ye, R, Maternal periconceptional body mass index and risk for neural tube defects: results from a large cohort study in China, The Journal of Maternal-Fetal & Neonatal Medicine, 2019, 2019, 1–7.
34. Avagliano, L, Mascherpa, M, Massa, V, Doi, P, Bulfamante, G.P, Fetal pancreatic Langerhans islets size in pregnancies with metabolic disorders, The Journal of Maternal-Fetal & Neonatal Medicine, 2018, 32(21), 3589-3594.
35. Dai, R, He, X.J, Hu, C.L, Maternal pre-pregnancy obesity and the risk of macrosomia: a meta-analysis, Archives of Gynecology and Obstetrics, 2018, 297(1), 139–145.
36. Chaemsaithong, P, Leung, T.Y, Sahota, D, Cheng YK, Leung WC, Lo TK et al. Body mass index at 11–13 weeks’ gestation and pregnancy complications in a Southern Chinese population: a retrospective cohort study, The Journal of Maternal-Fetal & Neonatal Medicine, 2018, 32(12), 1–13.
37. Huang, Y, Ouyang, Y.Q, Redding, S.R, Maternal Prepregnancy Body Mass Index, Gestational Weight Gain, and Cessation of Breastfeeding: A Systematic Review and Meta-Analysis, Breastfeeding Medicine, 2019, 14 (6), 366-374.
38. Rasmussen, K.M, Kjolhede, C.L, Prepregnant overweight and obesity diminish the prolactin response to suckling in the first week postpartum, Pediatrics, 2014, 113, 465-71.
39. Matias, S.R, Dewey, K.G, Quesenberry, C.P, Gunderson, E.P, Maternal prepregnancy obesity and insulin treatment during pregnancy are independently associated with delayed lactogenesis in women with recent gestational diabetes Mellitus, American Journal of Clinical Nutrition, 2014, 99, 115-21.
40. Nissen, E, Uvnäs-Moberg, K, Svensson, K, Stock, S, Widström, A.M, Winberg, J, Different patterns of oxytocin, prolactin but not cortisol release during breastfeeding in women delivered by caesarean section or by the vaginal route, Early Human Development, 2016, 45, 103-18.
41. Jevitt, C, Pregnancy Complicated by Obesity: Midwifery Management, J Midwifery Womens Health, 2017, 54(6), 445-451.
42. Özcan, A, Töz, E, Halksever, Özvatan, S, Vural, T, Sancı, M, Obez Gebeliklerin Yönetimi, Tepecik Eğit. ve Araşt. Hast. Dergisi, 2016, 26(1),1-9.
43. Blumfield, M.L, Hure, A.J, Macdonald-Wicks, L, Smith, R, Collins, C.E, Systematic review andmeta-analysis of energy andmacronutrient intakes during pregnancy in developed countries, Nutr Rev, 2012, 70, 322–36.
44. Adamo, K.B, Ferraro, Z.M, Goldfield, G, Keely, E, Stacey, D, Hadjiyannakis, S, et al. The Maternal Obesity Management (MOM) Trial Protocol: A lifestyle intervention during pregnancy to minimize downstream obesity, Contemporary Clinical Trials, 2013, 35(1), 87–96.
45. Olafsdottir, A.S, Skuladottir, G.V, Thorsdottir, I, Hauksson, A, Steingrimsdottir, L, Maternal diet in early and late pregnancy in relation toweight gain, Int J Obes (Lond), 2006, 30, 492–9.
46. Uusitalo, U, Arkkola, T, Ovaskainen, M.L, Kronberg-Kippilä, C, Kenward, M.G, Veijola, R, et al. Unhealthy dietary patternsare associated with weight gain during pregnancy among Finnish women, Public Health Nutr, 2009, 12, 2392–9.
47. O’Malley, E, Reynolds, C, Cawley, S, Woodside, J.V, Molloy, A.M, Turner, M.J, Folate and vitamin B12 levels in early pregnancy and maternal obesity, European Journal of Obstetrics & Gynecology and Reproductive Biology, 2018, 231, 80-84.
48. Crowther, C.A, Hiller, J.E, Moss, J.R, McPhee, A.J, Jeffries, W.S, Robinson, J.S, Effect of treatment of gestational diabetes mellitus on pregnancy outcomes, N Engl J Med, 2005, 352, 2477–86.

Ayrıntılar

Birincil Dil

Türkçe

Konular

Klinik Tıp Bilimleri

Bölüm

Derleme

Yazarlar

Büşra Demirer ^*
0000-0003-1945-0485
Türkiye

Hülya Yardımcı Bu kişi benim
0000-0002-2664-4176
Türkiye

Yayımlanma Tarihi

30 Eylül 2020

Gönderilme Tarihi

5 Şubat 2020

Kabul Tarihi

1 Haziran 2020

Yayımlandığı Sayı

Yıl 2020 Cilt: 7 Sayı: 3

DOI

https://doi.org/10.34087/cbusbed.685203

IZ

https://izlik.org/JA92PF88AG

Kaynak Göster

RIS / Bibtex

APA

Demirer, B., & Yardımcı, H. (2020). Maternal ve Fetal Sağlık İçin Büyük Tehlike: Maternal Obezite. Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi, 7(3), 401-407. https://doi.org/10.34087/cbusbed.685203

AMA

1.Demirer B, Yardımcı H. Maternal ve Fetal Sağlık İçin Büyük Tehlike: Maternal Obezite. CBU-SBED. 2020;7(3):401-407. doi:10.34087/cbusbed.685203

Chicago

Demirer, Büşra, ve Hülya Yardımcı. 2020. “Maternal ve Fetal Sağlık İçin Büyük Tehlike: Maternal Obezite”. Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi 7 (3): 401-7. https://doi.org/10.34087/cbusbed.685203.

EndNote

Demirer B, Yardımcı H (01 Eylül 2020) Maternal ve Fetal Sağlık İçin Büyük Tehlike: Maternal Obezite. Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi 7 3 401–407.

IEEE

[1]B. Demirer ve H. Yardımcı, “Maternal ve Fetal Sağlık İçin Büyük Tehlike: Maternal Obezite”, CBU-SBED, c. 7, sy 3, ss. 401–407, Eyl. 2020, doi: 10.34087/cbusbed.685203.

ISNAD

Demirer, Büşra - Yardımcı, Hülya. “Maternal ve Fetal Sağlık İçin Büyük Tehlike: Maternal Obezite”. Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi 7/3 (01 Eylül 2020): 401-407. https://doi.org/10.34087/cbusbed.685203.

JAMA

1.Demirer B, Yardımcı H. Maternal ve Fetal Sağlık İçin Büyük Tehlike: Maternal Obezite. CBU-SBED. 2020;7:401–407.

MLA

Demirer, Büşra, ve Hülya Yardımcı. “Maternal ve Fetal Sağlık İçin Büyük Tehlike: Maternal Obezite”. Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi, c. 7, sy 3, Eylül 2020, ss. 401-7, doi:10.34087/cbusbed.685203.

Vancouver

1.Büşra Demirer, Hülya Yardımcı. Maternal ve Fetal Sağlık İçin Büyük Tehlike: Maternal Obezite. CBU-SBED. 01 Eylül 2020;7(3):401-7. doi:10.34087/cbusbed.685203