Cytomegalovirus Infection Seen After Eosinophilic Granulomatosis With Polyangiitis – A Case Report

Abstract

Eosinophilic granulomatosis with polyangiitis (EGPA) also known as Churg- Strauss syndrome is a systemic small- and medium-vessel necrotizing vasculitis, characterized by extravascular granulomas, and eosinophilia. Treatment is primarily with corticosteroids and, for severe disease, addition of other immunosuppressive agents. Here, Here, we want to present a 57-year-old male patient who was diagnosed with EGPA and developed an opportunistic infection as the cause of hepatitis after treatment. Cytomegalovirus (CMV) is a common cause of opportunistic infection and can cause various symptoms and even mortality in immunocompromized patients. It is rarely cause of acute hepatitis. Opportunistic infections may cause vasculitis as well as reactivate after immunosuppressed treatments.

Keywords

• Eosinophilic granulomatosis with polyangiitis (EGPA)
• Cytomegalovirus
• acute hepatitis

Supporting Institution

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Project Number

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Thanks

Thanks to all authors

Eosinofilik Granülomatoz Polyangiitis Sonrası Görülen Sitomegalovirus Enfeksiyonu - Olgu Sunumu

Abstract

Churg-Strauss Sendromu olarak da bilinen eozinofilik granülomatozis polianjit (EGPA), ekstravasküler granülomlar ve eozinofili ile karakterize, küçük ve orta damarları tutan sistemik nekrotizan bir vaskülittir. Vaskülitin tedavisi esas olarak kortikosteroidlerle olur ve şiddetli hastalık tablosunda diğer immünosüpresif ajanlar eklenebilir. Burada, EGPA tanısı alan 57 yaşında bir erkek hastayı ve tedavi sonrası görülen hepatit nedeni olarak fırsatçı bir enfeksiyon gelişen olguyu sunmak istedik Cytomegalovirus (CMV), sık görülen fırsatçı enfeksiyon nedenidir ve bağışıklığı baskılanmış hastalarda çeşitli semptomlara ve hatta ölüme neden olabilir. Nadiren akut hepatite de neden olmaktadır Fırsatçı enfeksiyonlar, vaskülite neden olabildiği gibi immünsüprese tedaviler sonrası da reaktive olabilir.

Keywords

• Cytomegalovirus
• Eozinofilik granülomatöz polianjitis (EGPA)
• akut hepatit

Project Number

NO

References

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