Research Article

A fractional order model of hepatitis B transmission under the effect of vaccination

Volume: 71 Number: 2 June 30, 2022
EN

A fractional order model of hepatitis B transmission under the effect of vaccination

Abstract

In this paper we present a fractional order mathematical model to explain the spread of Hepatitis B Virus (HBV) in a non-constant population. The model we propose includes both vertical and horizontal transmission of the infection and also vaccination at birth and vaccination of the susceptible class. We also use a frequency dependent transmission rate in the model. We give results on existence of equilibrium points of the model and analyze the stability of the disease-free equilibrium. Finally, numerical simulations of the model are presented.

Keywords

References

  1. Anderson, R. M., May, R. M., Vaccination and herd immunity, Nature, 318 (1985), 323-329.
  2. Diekmann, O., Heesterbeek, J. A. P., Metz, J. A. J., On the definition and computation of the basic reproduction ratio $R_{0}$ in models for infectious diseases in heterogeneous populations, J. Math. Biol., 28 (1990), 365-382.
  3. Ding, Y., Ye, H., A fractional-order differential equation model of HIV infection of $CD4^{+}T-$Cells, Mathematical and Computer Modeling, 50 (2009), 386-392.
  4. El-Saka, H. A. A., The fractional-order SIS epidemic model with variable population size, Journal of Egyptian Mathematical Society, 22(1) (2014), 50-54.
  5. European Center for Disease Prevention and Control, Hepatitis B - Annual Epidemiological Report (2016). https://www.ecdc.europa.eu/en/publications-data/hepatitis-b-annual epidemiological-report-2016-2014-data / Accessed 21.09.2020.
  6. Farman, M., Ahmad, A., Umer, S. A., Hafeez, A., A mathematical analysis and modeling of hepatitis B model with non-integer time fractional derivative, Communications in Mathematics and Applications, 10(3) (2019), 571-584.
  7. Fattorich, G., Bortolotti, F., Donato, F., Natural history of chronic hepatitis B: special emphasis on disease progression and prognostic factors, J. Hepatol., 48(2) (2008), 335-352. doi: 10.1016/j.jhep.2007.11.011
  8. Ferrari, M. J., Perkins, S. E., Pomeroy, L. W., Bjornstad, O. N., Pathogens, social networks, and the paradox of transmission scaling, Interdisciplinary Perspectives on Infectious Diseases, Article ID 267049 (2011). doi:10.1155/2011/267049.

Details

Primary Language

English

Subjects

Applied Mathematics

Journal Section

Research Article

Publication Date

June 30, 2022

Submission Date

April 14, 2022

Acceptance Date

May 31, 2022

Published in Issue

Year 2022 Volume: 71 Number: 2

APA
Demirci, E. (2022). A fractional order model of hepatitis B transmission under the effect of vaccination. Communications Faculty of Sciences University of Ankara Series A1 Mathematics and Statistics, 71(2), 566-580. https://doi.org/10.31801/cfsuasmas.1103630
AMA
1.Demirci E. A fractional order model of hepatitis B transmission under the effect of vaccination. Commun. Fac. Sci. Univ. Ank. Ser. A1 Math. Stat. 2022;71(2):566-580. doi:10.31801/cfsuasmas.1103630
Chicago
Demirci, Elif. 2022. “A Fractional Order Model of Hepatitis B Transmission under the Effect of Vaccination”. Communications Faculty of Sciences University of Ankara Series A1 Mathematics and Statistics 71 (2): 566-80. https://doi.org/10.31801/cfsuasmas.1103630.
EndNote
Demirci E (June 1, 2022) A fractional order model of hepatitis B transmission under the effect of vaccination. Communications Faculty of Sciences University of Ankara Series A1 Mathematics and Statistics 71 2 566–580.
IEEE
[1]E. Demirci, “A fractional order model of hepatitis B transmission under the effect of vaccination”, Commun. Fac. Sci. Univ. Ank. Ser. A1 Math. Stat., vol. 71, no. 2, pp. 566–580, June 2022, doi: 10.31801/cfsuasmas.1103630.
ISNAD
Demirci, Elif. “A Fractional Order Model of Hepatitis B Transmission under the Effect of Vaccination”. Communications Faculty of Sciences University of Ankara Series A1 Mathematics and Statistics 71/2 (June 1, 2022): 566-580. https://doi.org/10.31801/cfsuasmas.1103630.
JAMA
1.Demirci E. A fractional order model of hepatitis B transmission under the effect of vaccination. Commun. Fac. Sci. Univ. Ank. Ser. A1 Math. Stat. 2022;71:566–580.
MLA
Demirci, Elif. “A Fractional Order Model of Hepatitis B Transmission under the Effect of Vaccination”. Communications Faculty of Sciences University of Ankara Series A1 Mathematics and Statistics, vol. 71, no. 2, June 2022, pp. 566-80, doi:10.31801/cfsuasmas.1103630.
Vancouver
1.Elif Demirci. A fractional order model of hepatitis B transmission under the effect of vaccination. Commun. Fac. Sci. Univ. Ank. Ser. A1 Math. Stat. 2022 Jun. 1;71(2):566-80. doi:10.31801/cfsuasmas.1103630

Cited By

Communications Faculty of Sciences University of Ankara Series A1 Mathematics and Statistics

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