Neuropsychiatric evaluation in HIV positive patients: a preliminary study
Öz
Purpose: The aim of this study was to assess neuropsychiatric symptoms of HIV infected patients and determine related socio-demographic and clinical features.
Material and Methods: A total of 10 HIV (+) outpatients who have been followed in Department of Infectious Diseases and Clinical Microbiology, Cukurova University Medical School were included in the study. To evaluate cognitive functions, a neuropsychological test battery consisted of 8 tests were administered. All patients completed Symptom Check List (SCL-90) to determine psychological symptoms and Hamilton Depression Rating Scale (HAM-D) were used to evaluate the severity of depression.
Results: The sample included 10 patients (4 females, 6 males). All patients had low or mid socioeconomic status, one half were married and seven patients had high or more level education. Executive functions and memory were impaired secondary to attentional narrowing in all HIV infected patients. Four patients were not diagnosed as depression (HAM-D<7) and other had mild to moderate depression. Only one patient was using an antidepressant medication. Others were neither referred for a psychiatric assessment, nor took a psychiatric treatment. Depression, obsessive-compulsive symptoms, somatization and interpersonal sensitivity subscales found to be high as were measured by SCL-90.
Conclusion: Cognitive impairment and depression is highly prevalent in HIV (+) patients and have negative effects on treatment adherence, psychosocial functioning and quality of life, so these disorders should be examined in regular psychiatric interviews and be treated regardless infection and its treatment.
Anahtar Kelimeler
Kaynakça
- 1. Sadock BJ, Sadock VA (Çeviri ed. Ali Bozkurt). Kaplan ve Sadock Klinik Psikiyatri El kitabı. Dördüncü Baskı. Güneş Tıp Kitapevi. Ankara. 2009.
- 2. AIDS Epidemic Update 2009. http://data.unaids.org/pub/report/2009/jc1700_epi_update_2009_en.pdf
- 3. Türkiye’de HIV/AIDS vakalarının dağılımı (Aralık 2012) http://www.hatam.hacettepe.edu.tr/verilerAralik2012.pdf
- 4. Bakım B, Özçelik B, Karamustafalıoğlu KO. HIV ile Enfekte Hastalarda Gözlenen Psikiyatrik Bozukluklar. Düşünen Adam. 2005; 18(3):149-156.
- 5. Gongvatana A, Woods SP, Taylor MJ, Vigil O, Grant I (The HNRC Group). Semantic Clustering Inefficiency in HIV Associated Dementia. The Journal of Neuropsychiatry and Clinical Neurosciences. 2007; 19:36–42.
