Relationship of blood eosinophil count to disease activity and inflammatory markers in patients with rheumatoid arthritis
Öz
Purpose: The aim of this study is to determine the frequency of eosinophilia among rheumatoid arthritis patients, as well as to evaluate the relation of eosinophil count to disease activity and inflammatory markers.
Material and Methods: Patients with rheumatoid arthritis who had admitted to the Physical Medicine and Rehabilitation out-patient clinic between January2016-March 2016 were included in the study. The demographic and clinical variables, along with the peripheral eosinophil count per microliter, eosinophil percentage, erythrocyte sedimentation rate (mm/h) and C-reactive protein level were recorded. Eosinophil count ≥ 500/microliter was regarded as eosinophilia. The disease activity was determined via the Disease Activity Score 28 (DAS28)-CRP.
Results: Sixty-two rheumatoid arthritis patients (54 female, 8 male) with a mean age of 54.0±12.2 years were included in the study. The median (minimum-maximum) value for eosinophil count and eosinophil percentage were 0.19 (0.01-0.8)/microliter and 2.45%(0.2-7.5), respectively. Eosinophilia was detected in 4.8% (n=3) of the patients. Eosinophil count showed no correlation with DAS28-CRP score, erythrocyte sedimentation rate and C-reactive protein level.
Conclusion: Eosinophilia is a rare occasion in rheumatoid arthritis. Peripheral blood eosinophil count appears not to be correlated with the disease activity or the inflammatory markers among patients with rheumatoid arthritis.Anahtar Kelimeler
Kaynakça
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