Severe hyponatremia and rhabdomyolysis associated with hypothyroidism
Abstract
Hyponatremia is one of the laboratory feature of hypothyroidism and usually occurs in elderly patients. In this report we presented a young patient with hypothyroidism induced severe hyponatremia and rhabdomyolysis. A nineteen-year-old woman was brought to the hospital with confusion. Because of acute hyponatremia with confusion, she was treated with hypertonic saline. The neurological examination returned to normal after treatment and fluid restriction, then serum sodium level increased to normal. Because of recurrent hyponatremia futher investigations were held. She was diagnosed as Hashimoto's thyroiditis. Hyponatremia improved with levothyroxine therapy and serum sodium level remained normal range. The elevated parameters of rhabdomyolysis decreased with levothyroxine therapy. Hypothyroidism should be considered in patients presenting with hyponatremia and rhabdomyolysis.
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