Hafif dereceli obstrüktif uyku apne sendromlu olgularda D vitamini suplemantasyonunun antropometrik ölçümler ve vücut bileşimine etkisi

Year 2021, , 371 - 380, 31.03.2021

Feride Ayyıldız , Hilal Yıldıran , Oğuz Köktürk

https://doi.org/10.17826/cumj.782576

Abstract

Amaç: Bu çalışma hafif dereceli obstrüktif uyku apne sendromu (OSAS) tanısı alan olgularda D vitamini suplemantasyonunun antropometik ölçümler ve vücut bileşimine etkisini incelemek amacıyla yapılmıştır.
Gereç ve Yöntem: Polisomnografi ile hafif dereceli OSAS tanısı alan ve D vitamini düzeyi yetersiz olan 20 yetişkin erkek (19-64 yıl) çalışmaya dahil edilmiştir. Olgulara sekiz hafta süresince 50.000 IU/hafta D3 vitamini suplemantasyonu verilmiştir. Çalışma başında ve sonunda tüm olguların bazı antropometrik ölçümleri (vücut ağırlığı, boy uzunluğu, bel, kalça ve boyun çevresi) alınmış ve vücut bileşimi analizleri yapılmıştır. Enerji ve besin ögesi alımları çalışma başında ve sonunda alınan 3 günlük bireysel besin tüketim kayıtları ile hesaplanmıştır.
Bulgular: Serum D vitamini düzeyi başlangıçta 19,1±5,16 ng/mL iken suplemantasyon sonrası 41,6±10,25 ng/mL’ye yükselmiş ve olguların %90’nın D vitamini düzeyi normal sınırlara ulaşmıştır. D vitamini suplemantasyonu sonunda olguların antropometrik ölçümleri ve vücut bileşimlerinde anlamlı fark olmamıştır. D vitamini suplemantasyonu sonunda diyet enerji, protein, yağ alımlarında ve apne hipopne indeksinde anlamlı azalma saptanmıştır.
Sonuç: Hafif dereceli obstrüktif uyku apne sendromu tanısı alan olgularda D vitamini suplemantasyonun enerji ve besin ögesi alımını etkileyebileceği görülmüştür. Ayrıca yetişkin olgularda D vitamini suplemantasyonunun hastalık prognozuna olumlu etkisinin olabileceği düşünülmektedir. Ancak D vitamininin vücut bileşimi ve antropometrik ölçümler üzerine etkisini incelemek amacıyla daha büyük örneklem ile uzunlamasına yapılacak çalışmalara ihtiyaç vardır.

Keywords

D vitamini, obstrüktif uyku apne sendromu, antropometrik ölçüm, vücut bileşimi

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Effect of vitamin D supplementation on anthropometric measurements and body composition in patients with mild obstructive sleep apnea syndrome

Abstract

Purpose: The aim of this study was to investigate the effect of vitamin D on anthropometric measurments and body composition in patients with mild obstructive sleep apnea syndrome (OSAS).
Materials and Methods: Twenty males (19-64 years) with mild OSAS after polysomnography and had low vitamin D levels were included. Patients were received weekly 50,000 IU vitamin D3 supplementation for eight weeks. Some anthropometric measurements of the patients (body weight, height, waist, hip and neck circumferences) and body composition measurements were taken. Three-day food records were taken from the patients. All measurements and records were taken both initial and end of the study.
Results: While serum vitamin D level was 19.1 ± 5.16 ng/mL at the beginning, it increased to 41.6 ± 10.25 ng / mL after supplementation. Also vitamin D level has reached normal limits in 90% of the patients. There was no significant difference in anthropometric measurement and body composition after vitamin D supplemantation. After vitamin D supplementation, a significant decrease was found in dietary energy, protein, fat intake and apnea hypopnea index.
Conclusion: Vitamin D supplementation may affect energy and nutrient intake in individuals diagnosed with mild obstructive sleep apnea syndrome. Also, vitamin D supplementation may have a positive effect on the disease prognosis. However, due to the effect of vitamin D on body composition and anthropometric measurements, longitudinal studies with larger sample are needed.

Keywords

obstructive sleep apnea, vitamin D

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