Abstract
Toxoplasmic encephalitis
is an opportunistic infection, which develops as a result of reactivation of
the latent tissue cysts of Toxoplasma gondii in patients with reduced CD4+ T
lymphocytes. Amongst patients with human immunodeficiency virus or acquired immunodeficiency
syndrome, toxoplasmic encephalitis is one of the leading causes of the
intracerebral involvement. In this report, we present a toxoplasmic
encephalitis case, who has admitted with neurological symptoms and fever. The
patient was identified human immunodeficiency virus positive while he was under
investigation for cerebral mass lesion, The patient has fully recovered by
antiprotozoal and antiretroviral therapy.
Keywords
References
- 1. Luft BJ, Hafner R, Korzun AH, Leport C, Antoniskis D, Bosler EM et al. Toxoplasmic encephalitis in patients with the acquired immunodeficiency syndrome. Members of the ACTG 077p/ANRS 009 Study Team. N Engl J Med. 1993;329:995-1000.
- 2. Belanger F, Derouin F, Grangeot-Keros L, Meyer L. Incidence and risk factors of toxoplasmosis in a cohort of human immunodeficiency virus-infected patients: 1988-1995. HEMOCO and SEROCO Study Groups. Clin Infect Dis. 1999;28:575-81.
- 3. Siddiqi OK, Koralnik IJ. Neurologic diseases caused by Human Immunodeficiency Virus Type 1 and opportunistic infections. In Mandell, Douglas and Bennett’s Principles and Practice of Infectious Diseases, Bennett JE, Dolin R, Blaser MJ (editors). 8th ed. Philadelphia: Saunders. 2015:1574-89.
- 4. Kiderlen TR, Liesenfeld O, Schurmann D, Schneider T. Toxoplasmic encephalitis in AIDS-patients before and after introduction of highly active antiretroviral therapy (HAART). Eur Clin Microbiol Infect Dis. 2011;30:1521-5.
Abstract
Toksoplazma ensefaliti
CD4+ T lenfosit sayısı azalmış olan hastalarda, Toxoplasma gondii’nin latent
halde bulunan doku kistlerinin reaktivasyonu ile ortaya çıkan fırsatçı bir
enfeksiyondur. Toksoplazma ensefaliti, insan immün yetmezlik virüsü enfeksiyonu
ve kazanılmış immün yetmezlik sendromu olan hastalarda, santral sinir sistemi
tutulumunun başta gelen nedenlerindendir. Bu yazıda , ateş ve nörolojik
bulgularla başvuran, radyolojik incelemeler sonucunda saptanan serebral
kitlenin etiyolojisi araştırılırken immün yetmezlik virüsü enfeksiyonu tanısı
konan ve antiretroviral ve antiprotozoal tedavi ile tam iyileşme sağlanan bir
toksoplazma ensefaliti olgusu sunulmuştur.
Keywords
References
- 1. Luft BJ, Hafner R, Korzun AH, Leport C, Antoniskis D, Bosler EM et al. Toxoplasmic encephalitis in patients with the acquired immunodeficiency syndrome. Members of the ACTG 077p/ANRS 009 Study Team. N Engl J Med. 1993;329:995-1000.
- 2. Belanger F, Derouin F, Grangeot-Keros L, Meyer L. Incidence and risk factors of toxoplasmosis in a cohort of human immunodeficiency virus-infected patients: 1988-1995. HEMOCO and SEROCO Study Groups. Clin Infect Dis. 1999;28:575-81.
- 3. Siddiqi OK, Koralnik IJ. Neurologic diseases caused by Human Immunodeficiency Virus Type 1 and opportunistic infections. In Mandell, Douglas and Bennett’s Principles and Practice of Infectious Diseases, Bennett JE, Dolin R, Blaser MJ (editors). 8th ed. Philadelphia: Saunders. 2015:1574-89.
- 4. Kiderlen TR, Liesenfeld O, Schurmann D, Schneider T. Toxoplasmic encephalitis in AIDS-patients before and after introduction of highly active antiretroviral therapy (HAART). Eur Clin Microbiol Infect Dis. 2011;30:1521-5.
Details
| Subjects | Health Care Administration |
|---|---|
| Journal Section | Case Report |
| Authors | |
| Publication Date | March 31, 2017 |
| Acceptance Date | September 19, 2016 |
| Published in Issue | Year 2017 Volume: 42 Issue: 1 |
