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Clinical features of primary orbital masses and their impact on visual functions

Year 2019, Volume: 44 Issue: Supplement 1, 86 - 91, 29.12.2019

Abstract

Purpose: The aim of this study is to identify clinical features of patients with primary orbital mass and evaluate how visual function parameters change following treatment.

Materials and Methods: Medical records of patients with primary orbital mass were retrospectively investigated. All patients were evaluated with ophthalmological examination including visual acuity, visual field, fundus and color vision before and after 3 months of surgery.

Results: Of the 55 patients included in the study, 45 (81.8%) had tumoral and 10 (18.2%) had non tumoral masses. Most common lesion was dermoid cyst in all orbital masses (32.7%). Of the tumoral masses, 66.7% were benign and 33.3% were malign. Most common presenting symptom was proptosis (40%). Compared with control eyes, eyes with orbital masses had significantly lower visual acuity and visual field (values and significantly higher fundus changes and color vision impairment. Compared with before treatment, eyes with orbital masses had significantly higher visual acuity and visual field values and significantly lower fundus changes  and color vision impairment (after surgery.  

Conclusion: Primary orbital massess have negative impacts on visual function. Significant improvement in visual functions could be seen after treatment of primary orbital masses.


References

  • Shields JA, Bakewell B, Augsburger JJ, Flanagan JC. Classification and incidence of space-oocupying lesions of the orbit. A survey of 645 biopsies. Arch Ophthalmol. 1984;102:1606-11.
  • Şendül SY, Dirim B, Alkan A, Üçgül Atılgan C, Yılmaz A, Olgun A ve ark. İntraorbital yer kaplayıcı lezyonlar: Klinik, radyolojik ve patolojik sonuçları. ŞEEAH Tıp Bülteni. 2017;51:322-8.
  • Bonavolonta G, Strianese D, Grassi P, Comune C, Tranfa F, Uccello G et al. An analysis of 2480 space-occupying lesions of the orbit from 1976 to 2011. Ophthalmic Plastic Reconstr Surg. 2013;29:79-86.
  • Alswaina N, Elkhamary SM, Shammari MA, Khan AO. Ophthalmic features of outpatient children diagnosed with intracranial space-oocupying lesions by ophthalmologists. Middle East Afr J Ophthalmol. 2015;22:327-30.
  • Sharma V, Betharia SM. Prospective evaluation of fundus changes in patients with orbital mass lesions. Retina. 2006;26:415-21.
  • Singh D, Pushker N, Bajaj MS, Saxena R, Sharma S, Ghose S. Visual function alterations in orbital tumors and factors predicting visual outcome after surgery. Eye (Lond). 2012;26:448-53.
  • Montano N, Lauretti L, D’Alessandris QG, Rigante M, Pignotti F, Olivi A et al. Orbital tumors: Report of 70 surgically treated cases. World Neurosurg. 2018;119:e449-58.
  • Shields JA, Shields CL, Scartozzi R. Survey of 1264 patients with orbital tumors and simulating lesions: The 2002 Montgomery Lecture, part 1. Ophthalmology. 2004;111:997-1008.
  • Domingo RE, Manganip LE, Castro RM. Tumors of the eye and ocular adnexa at the Philippine Eye Research Institute:a 10-year review. Clin Ophthalmol. 2015;9:1239-47.
  • Ben Simon GJ, Yoon MK, Atul J, Nakra T, McCann JD, Goldberg RA. Clinical manifestations of orbital mass lesions at the Jules Stein Eye Institute, 1999-2003. Ophthalmic Surg Lasers Imaging. 2006;37:25-32.
  • Masud MZ, Babar TF, Iqbal A, Khan MT, Zaffar ul Islam, Khan MD. Proptosis: etiology and demographic patterns. J Coll Physicians Surg Pak. 2006;16:38-41.
  • Yarovoy AA, Bulgakova ES, Shatskikh AV, Uzunyan DG, Kleyankina SS, Golubeva OV. CORE needle biopsy of orbital tumors. Graefes Arch Clin Exp Ophthalmol. 2013;251:2057-61.
  • Wei R, Li Y, Zhou Y. Automated perimetry analysis of optic nerve compression caused by orbital tumors and tumor-like lesions. Zhonghua Yan Ke Za Zhi. 1997;33:33–35.
  • Friberg TR, Grove AS. Choroidal folds and refractive errors associated with orbital tumors. An analysis. Arch Ophthalmol. 1983;101:598–603.

Primer orbital kitlelerin klinik özellikleri ve görme fonksiyonları üzerine etkisi

Year 2019, Volume: 44 Issue: Supplement 1, 86 - 91, 29.12.2019

Abstract

Amaç: Primer orbital kitlesi olan hastaların klinik özelliklerini belirlemek ve mevcut görme fonksiyon değerlerinin tedavi sonrası nasıl değiştiğini değerlendirmektir.

Gereç ve Yöntemler: Primer orbital kitle nedeniyle kliniğimize başvuran hastaların kayıtları retrospektif olarak incelendi. Tüm hastalar operasyon öncesinde ve operasyon sonrası 3. ayda görme keskinliği, görme alanı, fundus ve renkli görmeyi içeren oftalmolojik muayene ile değerlendirildi.

Bulgular: Çalışmaya katılan 55 hastanın 45’inde (%81.8) orbital kitle tümör kökenli iken 10 (%18.2) hastada ise non tümöral kitle şeklindeydi. Tüm orbital kitleler arasında en sık saptanan lezyon dermoid kistti (%32.7). Tümöral kitlelerin %66.7’si benign, %33.3’ü malign kaynaklıydı. Hastalarda en sık karşılaşılan semptom proptozisdi (%40). Orbital kitlesi olan gözlerde kontrol gözlerle karşılaştırıldığında görme keskinliği  ve görme alanı değerlerinin (istatistiksel olarak anlamlı derecede daha düşük, fundus değişikliklerinin ve renkli görmede bozulmanın ise istatistiksel olarak anlamlı derecede daha fazla olduğu bulundu. Orbital kitlesi olan gözler tedavi öncesi ve sonrası görme fonksiyonları açısından karşılaştırıldığında görme keskinliği ve görme alanı değerlerinde istatistiksel olarak anlamlı derecede artma, fundus değişikliklerinde ve renkli görmede ise istatistiksel olarak anlamlı derecede azalma saptandı.

Sonuç: Primer orbital kitlelerin görme fonksiyonları üzerine olumsuz etkileri bulunmaktadır. Primer orbital kitlelerin tedavisi sonrasında görme fonksiyonlarında anlamlı derecede düzelme gözlenmektedir.

References

  • Shields JA, Bakewell B, Augsburger JJ, Flanagan JC. Classification and incidence of space-oocupying lesions of the orbit. A survey of 645 biopsies. Arch Ophthalmol. 1984;102:1606-11.
  • Şendül SY, Dirim B, Alkan A, Üçgül Atılgan C, Yılmaz A, Olgun A ve ark. İntraorbital yer kaplayıcı lezyonlar: Klinik, radyolojik ve patolojik sonuçları. ŞEEAH Tıp Bülteni. 2017;51:322-8.
  • Bonavolonta G, Strianese D, Grassi P, Comune C, Tranfa F, Uccello G et al. An analysis of 2480 space-occupying lesions of the orbit from 1976 to 2011. Ophthalmic Plastic Reconstr Surg. 2013;29:79-86.
  • Alswaina N, Elkhamary SM, Shammari MA, Khan AO. Ophthalmic features of outpatient children diagnosed with intracranial space-oocupying lesions by ophthalmologists. Middle East Afr J Ophthalmol. 2015;22:327-30.
  • Sharma V, Betharia SM. Prospective evaluation of fundus changes in patients with orbital mass lesions. Retina. 2006;26:415-21.
  • Singh D, Pushker N, Bajaj MS, Saxena R, Sharma S, Ghose S. Visual function alterations in orbital tumors and factors predicting visual outcome after surgery. Eye (Lond). 2012;26:448-53.
  • Montano N, Lauretti L, D’Alessandris QG, Rigante M, Pignotti F, Olivi A et al. Orbital tumors: Report of 70 surgically treated cases. World Neurosurg. 2018;119:e449-58.
  • Shields JA, Shields CL, Scartozzi R. Survey of 1264 patients with orbital tumors and simulating lesions: The 2002 Montgomery Lecture, part 1. Ophthalmology. 2004;111:997-1008.
  • Domingo RE, Manganip LE, Castro RM. Tumors of the eye and ocular adnexa at the Philippine Eye Research Institute:a 10-year review. Clin Ophthalmol. 2015;9:1239-47.
  • Ben Simon GJ, Yoon MK, Atul J, Nakra T, McCann JD, Goldberg RA. Clinical manifestations of orbital mass lesions at the Jules Stein Eye Institute, 1999-2003. Ophthalmic Surg Lasers Imaging. 2006;37:25-32.
  • Masud MZ, Babar TF, Iqbal A, Khan MT, Zaffar ul Islam, Khan MD. Proptosis: etiology and demographic patterns. J Coll Physicians Surg Pak. 2006;16:38-41.
  • Yarovoy AA, Bulgakova ES, Shatskikh AV, Uzunyan DG, Kleyankina SS, Golubeva OV. CORE needle biopsy of orbital tumors. Graefes Arch Clin Exp Ophthalmol. 2013;251:2057-61.
  • Wei R, Li Y, Zhou Y. Automated perimetry analysis of optic nerve compression caused by orbital tumors and tumor-like lesions. Zhonghua Yan Ke Za Zhi. 1997;33:33–35.
  • Friberg TR, Grove AS. Choroidal folds and refractive errors associated with orbital tumors. An analysis. Arch Ophthalmol. 1983;101:598–603.
There are 14 citations in total.

Details

Primary Language Turkish
Subjects Ophthalmology
Journal Section Research
Authors

Meryem Altın Ekin 0000-0002-0395-7700

Publication Date December 29, 2019
Acceptance Date May 12, 2019
Published in Issue Year 2019 Volume: 44 Issue: Supplement 1

Cite

MLA Altın Ekin, Meryem. “Primer Orbital Kitlelerin Klinik özellikleri Ve görme Fonksiyonları üzerine Etkisi”. Cukurova Medical Journal, vol. 44, 2019, pp. 86-91.