Akut iskemik inmeli hastalarda repolarizasyon parametreleri ile inme şiddeti arasındaki ilişki

Yıl 2019, Cilt: 44 Sayı: Ek 1, 539 - 546, 29.12.2019

Ünal Öztürk Önder Öztürk Yusuf Tamam

https://doi.org/10.17826/cumj.572533

Öz

Amaç:  Bu çalışmanın amacı, akut iskemik inmeli hastalarda NIHSS ile repolarizasyon parametreleri arasındaki ilişkiyi araştırmak.

Gereç ve Yöntem: Çalışmaya akut iskemik inme geçiren 97 hasta (erkek,42; kadın,55; yaş, 65 ± 16) alındı. 17 hasta çalışmadan çıkarıldı. NIHSS skoruna göre hastalar iki gruba ayrıldı (Grup 1, NIHSS skor <16; Grup 2, NIHSS skoru ≥ 16).  Bütün hastalardan demografik, klinik ve laboratuvar verileri toplandı. Hastaların 12 derivasyonlu EKG’leri nöroloji yoğun bakım ünitesine yatırıldıktan hemen sonra çekildi. Ölçümler cetvelle yapıldı. QTc, QTd, QTcd, Tpe, Tpe/QT parametreleri ölçüldü.

Bulgular: Hastaların demografik özellikleri açısından gruplar arasında anlamlı farklılık saptanmadı. Hastaların QTc, QTd, QTcd, Tpe, Tpe/QT parametreleri, Grup 2 hastalarında, Grup 1 hastalarına göre anlamlı derecede daha yüksek bulundu.

Sonuç: Yapmış olduğumuz bu çalışmada, akut iskemik inmeli hastalarda repolarziasyon parametrelerinin inme şiddeti ile ilişkili olduğu sonucuna varılabilir. Bu çalışmada, akut iskemik inmenin repolarizasyon parametrelerinde değişikliğe neden olduğunu bulduk. Repolarizasyon parametreleri, akut iskemik inmeli hastaların yatış esnasındaki inme şiddeti ile ilişkilidir. Repolarizasyon parametrelerinin dispersiyonundaki artış, akut iskemik inmeli hastalarda aritmik kardiyak ölüm riskine bağımsız bir şekilde katkıda bulunmaktadır. Bu nedenle, özellikle ciddi iskemik inmeli hastaların, ilk 24 saatte yakın kardiyak monitorizasyonunu önermekteyiz.

Anahtar Kelimeler

Repolarizasyon parametreleri, inme şiddeti, inme

Relationship between stroke severity and repolarization parameters in patients with acute ischemic stroke

Öz

Purpose: The aim of this study was to investigate the relationship between repolarization parameters and National Institutes of Health Stroke Scale (NIHSS) score in patients with acute ischemic stroke. 

Materials and Methods: The study comprised 97 patients (males, 42; females, 55; 65 ± 16 years) with acute ischemic stroke. 17 patients were excluded. Patients were divided into two groups based on the calculated NIHSS score (Group 1, NIHSS score < 16; Group 2, NIHSS score ≥ 16). Demographic, clinical, and laboratory data for all patients were collected. A 12-lead resting ECG was recorded at admission to the neurology care unit in patients with acute ischemic stroke and were manually measured with a ruler. QTc, QTd, QTcd, Tpe, Tpe/QT parameters were measured. 

Results: There were no significant differences among demographic parameters of patients. We found that QTc, QTd, QTcd, Tpe, Tpe/QT parameters were significantly higher in Group 2 than Group 1 patients. 

Conclusion: In this study, we found that acute ischemic stroke has been shown to cause changes in repolarization parameters. Repolarization parameters are associated with stroke severity on admission in patients with acute ischemic stroke. Increased dispersion of repolarization parameters make independent contributions to the risk of arrhythmic cardiac death in patients with acute ischemic stroke. We suggested that especially severe ischemic stroke patients closely using cardiac monitoring during the first 24 h. 

Anahtar Kelimeler

Repolarization parameters, stroke severity, stroke

Kaynakça

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