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Pseudolipomatosis Coli: Case Report

Year 2014, Volume: 39 Issue: 1, 152 - 156, 22.07.2014
https://doi.org/10.17826/cutf.13568

Abstract

Pseudolipomatosis coli is an iatrogenic entity due to the endoscopic procedures which has an unclear pathogenesis. Mucosal damage, gas invasion or lymph extravasation caused by barotraumas resulting from endoscopic procedures or the effect of the colonoscopic disenfection products could be blamed in the pathogenesis. The terminology "pseudolipomatosis" has been used because of the similarity to the lipomatous tissue macroscopically and microscopically. Pseudolipomatosis can be observed in different parts of the gastrointestinal system from stomach to rectum and named as pseudolipomatosis coli when the entity is located in the colon like it is in the presented case. Histologically numerous cytics spaces with no epithelium are seen in the mucosa especially in the lamina propria. The case was presented as an entity in the differential diagnosis to keep in mind that it is important to avoid unnecessary treatment during the evaluation of endoscopic biopsies.

References

  • Brevet M, Chatelain D, Bartoli E, Geslin G, Delcenserie R, BraillonA, et al. Colonic pseudolipomatosis: clinical, endoscopical and pathological features in nine cases. Gastroenterol Clin Biol. 2006;30:9-13.
  • Bircan S, Başpınar Ş, Çiriş M, Kapucuoğlu N, Karahan N, Çandır Ö, et al. [Gastric pseudolipomatosis; Two case reports]. Turk J Path. 2005;21:21-3.
  • Alper M, Belenli OK, Çukur S, Aksoy KA, Suna M. Gastric pseudolipomatosis , usual or unusual? Reevaluation of 909 endoscopic gastric biopsies. World J Gastroenterol. 2003;9:2846-48.
  • Nakasono M, Hirokawa M, Muguruma N, Okamura S, Ito S, Iga A, et al. Colonic pseudolipomatosis, microscopically classified into two groups. J Gastroenterol Hepatol. 2006;21:65-70.
  • Lam-Himlin D, Arnold CA, Montgomery EA. Histopathology of iatrogenic injury in the colorectum. Diagn Histopathol. 2011;17:404-8.
  • Kim SJ, Baek IH. Colonic mucosal pseudolipomatosis: disinfectant colitis? Gastroenterol Nurs. 2012;35:208-13.
  • Snover DC, Sandstad J, Hutton S. Mucosal pseudolipomatosis of the colon. Am J Clin Pathol. 1985;84:575-80.
  • Cox ME, Bostwick DG. Mucosal plaques seen at colonoscopy: chemical colitis or mucosal pseudolipomatosis? Gastroenterol. 1989;96:1626-7.
  • Stebbing J, Wyatt JI. Gastric “pseudolipomatosis”. Histopathol. 1998;32:283-4.
  • Cook DS, Williams GT. Duodenal “pseudolipomatosis”. Histopathol. 1998;33:394-5.
  • Hornick JL, Odze RD. Polyps of large intestine. In: Odze RD, Goldblum JR, eds. Surgical Pathology of the GI Tract, Liver, Biliary Tract and Pancreas. 2 nd ed. China: Saunders Elsevier. 2009;530.
  • Fenoglio-Preiser CM, Noffsinger AE, Stemmermann GN, Lantz PE, Isaacson PG. Mesenchymal Tumors. Gastrointestinal Pathology: An Atlas and Text. 3 rd ed. China: Lippincott Williams&Wilkins.2008;1236-7.
  • Yazışma Adresi / Address for Correspondence: Dr. Deniz Tunçel İstanbul Şişli Hamidiye Etfal Eğitim ve Araştırma Hastanesi, Patoloji Bölümü İSTANBUL e-posta: email@deniztuncel.com geliş tarihi/received :25.09.2013 kabul tarihi/accepted:16.09.2013

Psödolipomatozis Koli: Olgu Sunumu

Year 2014, Volume: 39 Issue: 1, 152 - 156, 22.07.2014
https://doi.org/10.17826/cutf.13568

Abstract

Psödolipomatozis koli, patogenezi henüz net olarak bilinmeyen, gerçek bir patolojik tablodan çok endoskopik girişime bağlı gelişen iatrojenik bir durumdur. Endoskopik girişime bağlı barotravmaya veya kolonoskop temizleme solüsyonlarına bağlı gelişen mukozal hasar ve sonucunda lamina propriaya gaz invazyonu veya lenf sıvısının ekstravazasyonu patogenezde suçlanmaktadır. Yağ dokusuna makroskopik ve mikroskopik benzerliğinden dolayı psödolipomatozis terimi kullanılmaktadır. Mideden rektuma kadar gastrointestinal sistemin değişik bölgelerinde görülebilen psödolipomatozis, sunulan bu olguda olduğu gibi, kolonda görüldüğünde psödolipomatozis koli olarak adlandırılmaktadır. Histolojik olarak mukozada özellikle lamina propriada, döşeyici bir epitel bulundurmayan çok sayıda kistik boşluk olarak görülür. Gereksiz tedavilerin önlenmesi açısından, endoskopik biyopsi materyalleri değerlendirilirken, ayırıcı tanıda akılda tutulması gereken bir antite olması nedeni ile olgu sunulmaya değer görülmüştür.

References

  • Brevet M, Chatelain D, Bartoli E, Geslin G, Delcenserie R, BraillonA, et al. Colonic pseudolipomatosis: clinical, endoscopical and pathological features in nine cases. Gastroenterol Clin Biol. 2006;30:9-13.
  • Bircan S, Başpınar Ş, Çiriş M, Kapucuoğlu N, Karahan N, Çandır Ö, et al. [Gastric pseudolipomatosis; Two case reports]. Turk J Path. 2005;21:21-3.
  • Alper M, Belenli OK, Çukur S, Aksoy KA, Suna M. Gastric pseudolipomatosis , usual or unusual? Reevaluation of 909 endoscopic gastric biopsies. World J Gastroenterol. 2003;9:2846-48.
  • Nakasono M, Hirokawa M, Muguruma N, Okamura S, Ito S, Iga A, et al. Colonic pseudolipomatosis, microscopically classified into two groups. J Gastroenterol Hepatol. 2006;21:65-70.
  • Lam-Himlin D, Arnold CA, Montgomery EA. Histopathology of iatrogenic injury in the colorectum. Diagn Histopathol. 2011;17:404-8.
  • Kim SJ, Baek IH. Colonic mucosal pseudolipomatosis: disinfectant colitis? Gastroenterol Nurs. 2012;35:208-13.
  • Snover DC, Sandstad J, Hutton S. Mucosal pseudolipomatosis of the colon. Am J Clin Pathol. 1985;84:575-80.
  • Cox ME, Bostwick DG. Mucosal plaques seen at colonoscopy: chemical colitis or mucosal pseudolipomatosis? Gastroenterol. 1989;96:1626-7.
  • Stebbing J, Wyatt JI. Gastric “pseudolipomatosis”. Histopathol. 1998;32:283-4.
  • Cook DS, Williams GT. Duodenal “pseudolipomatosis”. Histopathol. 1998;33:394-5.
  • Hornick JL, Odze RD. Polyps of large intestine. In: Odze RD, Goldblum JR, eds. Surgical Pathology of the GI Tract, Liver, Biliary Tract and Pancreas. 2 nd ed. China: Saunders Elsevier. 2009;530.
  • Fenoglio-Preiser CM, Noffsinger AE, Stemmermann GN, Lantz PE, Isaacson PG. Mesenchymal Tumors. Gastrointestinal Pathology: An Atlas and Text. 3 rd ed. China: Lippincott Williams&Wilkins.2008;1236-7.
  • Yazışma Adresi / Address for Correspondence: Dr. Deniz Tunçel İstanbul Şişli Hamidiye Etfal Eğitim ve Araştırma Hastanesi, Patoloji Bölümü İSTANBUL e-posta: email@deniztuncel.com geliş tarihi/received :25.09.2013 kabul tarihi/accepted:16.09.2013
There are 13 citations in total.

Details

Primary Language Turkish
Journal Section Research
Authors

Deniz Tunçel This is me

Elmas Özgün This is me

Aysun Gökçe This is me

Nurten Bozlak This is me

Publication Date July 22, 2014
Published in Issue Year 2014 Volume: 39 Issue: 1

Cite

MLA Tunçel, Deniz et al. “Psödolipomatozis Koli: Olgu Sunumu”. Cukurova Medical Journal, vol. 39, no. 1, 2014, pp. 152-6, doi:10.17826/cutf.13568.