Abstract
Granulocytic sarcoma is an extramedullary tumor, frequently associated with acute myeloid leukemia or myeloproliferative neoplasm. This tumor occasionally occurs in any anatomical part of the body without a known hematolymphoid disorder. Gynecologic tract is one of the rare localization of this tumor. Isolated cervical granulocytic sarcoma is extremely rare. In this case report, we present clinical and pathological findings of a 37 years old women with isolated cervical granulocytic sarcoma without any hematolymphoid disorder evidence.
References
- Pathak B, Bruchim I, Brisson ML et al. Granulocytic sarcoma presenting as tumors of the cervix. Gynecol Oncol. 2005;98:493-7
- Yıldırım N, Turkmen K, Hatipoğlu E ve ark. Akut myeloid lösemi tanısından önce ortaya çıkan ve lenfoma ile karışabilen granülositik sarkom. İst Tıp Fak Derg. 2009;72:22-4
- Garcia MG, Deavers MT, Knoblok R ve ark. Myeloid sarcoma involving the gynecologic tract. Am J Clin Pathol. 2006;125:783-90
- Kim SC, Natarajan-Ame S, Lioure B, Chenard MP, Duclos B, Herbrecht R, Bergerat JP. Successful treatment of a granulocytic sarcoma of the uterine cervix in complete remission at six-year follow-up. J Oncol. 2010;2010:812424.
- Neiman RS, Barcos M, Berard C, Bonner H, Mann R, Rydell RE. Granulocytic sarcoma: a clinicopathologic study of 61 biopsied cases. Cancer. 1981;48:1426
- Lee JW, Kim YT, Min YH et al. Granulocytic sarcoma of the uterine cervix. In Gynecol Cancer. 14:553-557. Hernández JA, Navarro JT, Rozman M, Ribera JM, Rovira M, Bosch MA, Fantova MJ,Mate JL, Millá F. Primary myeloid sarcoma of the gynecologic tract: a report of two cases progressing to acute myeloid leukemia. Leuk Lymphoma. 2002;43:2151-3.
- Banik S, Grech AB, Eyden BP. Granulocytic sarcoma of the cervix: an immunohistochemical, histochemical, and ultrastructural study. J Clin Pathol.1989;42:483-8.
- Harris NL, Scully RE. Malignant lymphoma and granulocytic sarcoma of the uterus and vagina. A clinicopathologic analysis of 27 cases. Cancer. 1984;53:2530-45.
- Yazışma Adresi / Address for Correspondence: Dr. Arbil Açıkalın Çukurova Üniversitesi Tıp Fakültesi Patoloji Anabilim Dalı 01330, Balcalı Hastanesi Sarıçam/ADANA e mail: drfatih75@gmail.com geliş tarihi/received :24.09.2013 kabul tarihi/accepted:22.10.2013
Abstract
Granülositik sarkom genellikle akut myeloid lösemi veya myeloproliferatif neoplazilere eşlik eden ekstramedüller yerleşimli tümördür. Bu tümörler nadiren bilinen bir hematolenfoid hastalık olmaksızın herhangi bir anatomik bölgede ortaya çıkabilirler. Jinekolojik trakt, granülositik sarkomun görülebileceği bölgelerden biri olup izole servikal kitle şeklinde az sayıda olgu bildirilmiştir. Otuz yedi yaşında, primer tanısını serviks biyopsisi ile almış, rekürrens ve metastazlarla seyreden, ancak kemik iliği tutulumu göstermeyen olguyu literatür bilgileri eşliğinde tartışmayı amaçladık.
References
- Pathak B, Bruchim I, Brisson ML et al. Granulocytic sarcoma presenting as tumors of the cervix. Gynecol Oncol. 2005;98:493-7
- Yıldırım N, Turkmen K, Hatipoğlu E ve ark. Akut myeloid lösemi tanısından önce ortaya çıkan ve lenfoma ile karışabilen granülositik sarkom. İst Tıp Fak Derg. 2009;72:22-4
- Garcia MG, Deavers MT, Knoblok R ve ark. Myeloid sarcoma involving the gynecologic tract. Am J Clin Pathol. 2006;125:783-90
- Kim SC, Natarajan-Ame S, Lioure B, Chenard MP, Duclos B, Herbrecht R, Bergerat JP. Successful treatment of a granulocytic sarcoma of the uterine cervix in complete remission at six-year follow-up. J Oncol. 2010;2010:812424.
- Neiman RS, Barcos M, Berard C, Bonner H, Mann R, Rydell RE. Granulocytic sarcoma: a clinicopathologic study of 61 biopsied cases. Cancer. 1981;48:1426
- Lee JW, Kim YT, Min YH et al. Granulocytic sarcoma of the uterine cervix. In Gynecol Cancer. 14:553-557. Hernández JA, Navarro JT, Rozman M, Ribera JM, Rovira M, Bosch MA, Fantova MJ,Mate JL, Millá F. Primary myeloid sarcoma of the gynecologic tract: a report of two cases progressing to acute myeloid leukemia. Leuk Lymphoma. 2002;43:2151-3.
- Banik S, Grech AB, Eyden BP. Granulocytic sarcoma of the cervix: an immunohistochemical, histochemical, and ultrastructural study. J Clin Pathol.1989;42:483-8.
- Harris NL, Scully RE. Malignant lymphoma and granulocytic sarcoma of the uterus and vagina. A clinicopathologic analysis of 27 cases. Cancer. 1984;53:2530-45.
- Yazışma Adresi / Address for Correspondence: Dr. Arbil Açıkalın Çukurova Üniversitesi Tıp Fakültesi Patoloji Anabilim Dalı 01330, Balcalı Hastanesi Sarıçam/ADANA e mail: drfatih75@gmail.com geliş tarihi/received :24.09.2013 kabul tarihi/accepted:22.10.2013
Details
| Primary Language | Turkish |
|---|---|
| Journal Section | Research |
| Authors | |
| Publication Date | July 22, 2014 |
| Published in Issue | Year 2014 Volume: 39 Issue: 1 |
