Neurofibromatosis type 1 and autoimmune hyperthyroidism in a 10,5 years-old girl

Yıl 2013, Cilt: 38 Sayı: 4, 805 - 808, 01.12.2013

Hüseyin Demirbilek Serhan Küpeli Mehmet Nuri Özbek Semra Saygı Aysen Türedi Yıldırım

Öz

Neurofibromatosis type 1 (NF1) is an autosomal dominant inherited multisystem disease associated with several endocrine disorders. Association of NF1 and hyperthyroidism is extremely rare. All previously reported cases were in adult age group. Herein, we present autoimmune thyrotoxicosis associated to NF1 in a pediatric patient presenting with goiter and symptoms of thyrotoxicosis.

Anahtar Kelimeler

Keywords: Neurofibromatosis type 1, autoimmune hyperthyroidism, Graves" disease

Onbuçuk yaşındaki bir kız çocuğunda Nörofibromatoziz tip 1 ve otoimmün hipertiroidizm birlikteliği

Öz

Nörofibromatoziz tip 1 (NF1) endokrin bozuklukların eşlik ettiği otozomal dominant geçişli multisistem bir hastalıktır. Nörofibromatoziz tip 1 ve hipertiroidizm birlikteliği nadir görülen bir durumdur. Bugüne kadar yayınlanmış olgular genellikle erişkin yaş grubundandır. Bu yazıda guatr ve tirotoksikoz bulguları ile başvuran çocuk yaş grubu bir olguda otoimmün tirotoksikoz ve NF1 birlikteliği sunulmuştur.

Anahtar Kelimeler

Nörofibromatoziz tip 1, otoimmüne hipertiroidizm, Graves" hastalığı

Kaynakça

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