Wernicke Encephalopathy after Gastrointestinal Surgery

Year 2015, Volume: 40 Issue: 3, 627 - 631, 01.10.2015

Semra Saygı , Tülin Savaş Özlem Alkan Tülin Savaş Özlem Alkan İlknur Erol

https://doi.org/10.17826/cutf.25987

Abstract

We herein describe a child operated for acute abdomen who developed Wernicke's encephalopathy (WE) secondary to prolonged total parenteral nutrition (TPN) that lacked vitamin B1 supplementation. The author concluded that surgeons, child neurologists, pediatricians and radiologists need to be aware of the predisposing factors and symptoms of WE. Clinicians need to keep in mind that ophthalmoplegia, ataxia or altered mental status could be findings of WE.

Keywords

Wernicke's encephalopathy, encephalopathy, ataxia, ophthalmoplegia, total parenteral nutrition

Gastrointestinal Cerrahi Sonrası Gelişen Bir Wernicke Ensefalopatisi

Abstract

Bu yazıda akut batın nedeni ile opere olan, gastrointestinal cerrahi sonrası dönemde tiamin desteği olmaksızın, total parenteral beslenme alan ve Wernike ensefalopatisi (WE), gelişen olgu sunulmuştur. Cerrahların, çocuk nörologlarının, pediatristlerin ve radyologların, WE için risk faktörlerini ve hastalığın belirti ve bulgularını iyi bilmeleri, klinisyenlerin, oftalmopleji, ataksi veya mental durum değişikliklerinin WE’ne ait bulgular olabileceğini akılda tutmaları gerekir.

Keywords

Wernicke ensefalopatisi, ensefalopati, ataksi, oftalmopleji, total parenteral beslenme

References

• Victor, M, Adams, RA, Collins, GH. The Wernicke- Korsakoff syndrome and related disorders due to alcoholism and malnutrition. FA Davis, Philadelphia. 1989.
• Vasconcelos MM, Silva KP, Vidal G, Silva AF, Domingues RC, Berditchevsky CR. Early diagnosis of pediatric Wernicke’s encephalopathy. Pediatr Neurol. 1999;20:289-94.
• Francini-Pesenti F, Brocadello F, Manara R, Santelli L, Laroni A, Caregaro L. Wernicke’s syndrome during parenteral feeding: not an unusual complication. Nutrition. 2009;25:142-6.
• Kömür M, Gündoğdu G, Avlan D, Okuyaz Ç. Uzun
• Süreli Total Parenteral Beslenme Sonrası Wernicke Ensefalopatili Bir Vaka Sunumu. Çocuk Dergisi. 2011;11:26-28.
• Harper CG, Giles M, Finlay-Jones R. Clinical signs in the Wernicke-Korsakoff complex: a retrospective analysis of 131 cases diagnosed at necropsy. J Neurol Neurosurg Psychiatry. 1986;49:341.
• Martin PR, Singleton CK, Hiller-Sturmhöfel S. The role of thiamine deficiency in alcoholic brain disease. Alcohol Res Health. 2003;27:134.
• O'Keeffe ST. Thiamine deficiency in elderly people. Age Ageing. 2000;29:99.
• Antunez E, Estruch R, Cardenal C, et al. Usefulness of CT and MR imaging in the diagnosis of acute Wernicke's encephalopathy. AJR Am J Roentgenol. 1998;171:1131. 9. Zhang XP, Lu
• YQ, Huang WD. Wernicke
• encephalopathy following splenectomy in a patient
• with liver cirrhosis: a case report and review of the
• literature. J Zhejiang Univ Sci B. 2010;11:433-6.
• Sechi G, Serra A. Wernicke's encephalopathy: new clinical settings and recent advances in diagnosis and management. Lancet Neurol. 2007;6:442-55.
• Rufa A, Rosini F, Cerase A, et al. Wernicke encephalopathy after gastrointestinal surgery for cancer: causes of diagnostic failure or delay. Int J Neurosci. 2011;121:201-8.
• Francini-Pesenti F, Brocadello F, Famengo S, Nardi M, Caregaro L. Wernicke’s encephalopathy during parenteral nutrition. JPEN. 2007;31:69-71.
• Han JW, Lim S, Shin HS, Park HJ, Jung WJ, Kwon Two SY, Lyu CJ. cases of Wernicke's encephalopathy in young age patients receiving allogeneic hematopoietic stem cell transplantation.
• Yonsei Med J. 2012 ;53:1049-53.
• Ghez C. Vestibular paresis: a clinical feature of
• Wernicke's disease. J Neurol Neurosurg Psychiatry. 1969;32:134.