Peripheral Ameloblastoma with Mixed Histological Patterns

Year 2015, Volume: 40 Number: Supplement 1, 151 - 155, 09.10.2015

Manas Bajpai , Nilesh Pardhe

https://doi.org/10.17826/cutf.32647

Cited By: 2

Abstract

Peripheral ameloblastoma is a relatively uncommon neoplasm of odontogenic origin histologically resembles the classic ameloblastoma and derived from epithelial and/or mesenchymal elements being part of the tooth forming apparatus. It can be originated in the soft tissue of oral cavity namely alveolar mucosa or gingiva. Among histopathological pattern the most common is acanthomatous followed by plexiform and follicular. Granular cell ameloblastoma once considered as the most aggressive variant of ameloblastoma but according to the recent studies it is believed that the earlier belief was a myth. We report a case of peripheral ameloblastoma in a 44 year old lady, histopathologicaly showing combined features of granular cell, plexiform, acanthomatous, follicular and desmoplastic ameloblastoma. As per our best knowledge this is the first case of its type.

Keywords

Peripheral ameloblastoma, granular cell, acanthomatous, follicular, plexiform, desmoplastic

Kompleks Histolojik Paternler İçeren Periferal Ameloblastoma

Abstract

Periferal ameloblastoma, diş dokusu kaynaklı, klasik ameloblastomaya benzeyen, nispeten yaygın olmayan bir tümör olup dişi oluşturan yapıların bir parçası olarak epitel ve/veya mezenşimal elementlerden çoğalır. Alveolar mukoza veya gingiva olarak adlandırılan ağız boşluğunun yumuşak dokusundan köken alabilir. Histopatholojik sekiller arasında en yaygını, pleksiform ve foliküler tarafından takip edilen acanthomatousdur. Granüler hücre ameloblastoma'nın bir zamanlar ameloblastoma'nın en agressif formu olduğu düşünülürdü, ancak son dönemlerde yapılan çalışmalara göre önceki inanışların bir mit oluğu görüşü yaygınlaşmaya başladı. Kırk dört yaşındaki bir kadında, histopatolojik olarak granüler hücre, pleksiform, acanthomatous, foliküler ve desmoplastik ameloblastomanın kombinlenmiş özelliğini gösteren bir periferal ameloblastoma olgusu bildirilmiştir.

Keywords

Periferal Ameloblastoma, Granüler hücre, Acanthomatous, Foliküler, pleksiform, desmoplastik

References

• El-Mofty SK, Gerard NO, Farish SE, Rodu B. Peripheral ameloblastoma: a clinical and histologic study of 11 cases. J Oral Maxillofac Surg. 1991;49:970-4.
• Cj S, David CM, Kaul R, Bk R, Ramachandra P. Intraosseous ameloblastoma masquerading as exophytic growth: a case report. Imaging Sci Dent..2011; 41:89–93.
• Cranin AN, Benett J, Solomon M, Quarcoo S. Massive Granular cell ameloblastoma metastasis: Report of a case. J Oral Maxillofac Surg. 1987;45:800-4. with
• Wettan HL, Patella PA, Freedman PD. Peripheral ameloblastoma: review of the literature and report of recurrence as severe dysplasia. J Oral Maxillofac Surg. 2001;59:811-5.
• Orsini G, Fioroni M, Rubini C, Piattelli A. Peripheral ameloblastoma: a report of 2 cases. J Periodontol 2000;71:1174-6.
• Philipsen HP, Reichart PA, Nikai H, Takata T, Kudo Y. Peripheral ameloblastoma: biological profile based on 160 cases from the literature. Oral Oncol 2001;37:17-27.
• Rajaonarison Ny Ony N, Randriamarolahy A, Randrianjanahary OM, Ahmad A, Bruneton JN (2012)Giant ameloblastoma. 2012;36:146–8. Clin Imaging.
• Odontogenic tumors’WHO classification of tumors. Pathology and Genetics of Head and Neck Tumors. IARC: Lyon, 2006;297-98.
• Pekiner FN, Özbayrak S, Şener BC, Olgaç V,
• Sinanoğlu A. Peripheral ameloblastoma: a case report. Dentomaxillofac Radiol. 2007;36:183-6.
• Kishino M, Murakami S, Yuki M, Iida S, Ogawa Y, Kogo M, et al. A immunohistochemical study of the peripheral ameloblastoma. Oral Dis. 2007;13:575-80.
• Gardner DG, Heikinheimo K, Shear M, Philipsen HP, Coleman H. Ameloblastoma. In: Barnes L, Eveson J, Reichart P, Sidransky D, eds. World Health Organization classification of tumours; pathology and genetics of head and neck tumours. Lyon: IARC Press. 2005:296–300.
• Redman RS, Keegan BP, Spector CJ, Patterson RH. Peripheral ameloblastoma with unusual mitotic activity and conflicting evidence regarding histogenesis. J Oral Maxillofac Surg. 1994;52:192-7.
• Maria A, Sharma Y. Granular cell peripheral ameloblastoma: A rare case. Journal of Maxillofacial and Oral surgery. 2009;8:294–7.
• Gupta S, Grewal H, Sah K. Granular cell ameloblastoma showing desmoplasia. Ann Saudi Med. 2012;32:537–40.
• Cranin AN, Benett J, Solomon M, Quarcoo S. Massive Granular cell ameloblastoma with metastasis:Report of a case. J Oral Maxillofac Surg. 1987;45:800-4.
• Nasu M, Tagaki M, Yamamoto H. Ultrastructural and histochemical studies of granular cell ameloblastoma. J Oral Pathol. 1984;13:448-56.
• Tandler B, Rossi EP. Granular cell ameloblastoma: Electron microscopic observations. J Oral Pathol. 1977;6:401-12.
• Kumamoto H, Ohki K, Ooya K. Expression of p63 and p73 in ameloblastomas. J Oral Pathol Med. 2005;34:220-6.
• Smith J, Sollee N, Drake J, Blankenship J. Granular cell ameloblastoma with remarkable production. Oral Surg Oral Med Oral Pathol. 1966;21:499-505. mucin
• Bajpai M, Kumar M, Kumar M, Agarwal D. Pigmented Lesion of Buccal Mucosa. Case Reports in Medicine. 2014;2014:936142.
• Woods TR, Cohen DM, Islam MN, et al. Intraoral basal cell carcinoma, a rare neoplasm: report of three new cases with literature review. Head and Neck Pathology. 2014;8:339-348.