İdrar kültürü pozitif erken doğum ve erken membran rüptüründe doğum süresi ve olumsuz neonatal sonuçların değerlendirilmesi
Year 2020,
Volume: 45 Issue: 1, 39 - 47, 31.03.2020
Sibel Özler
,
Efser Öztaş
Derya Solmaz
Başak Gümüş Güler
Ali Özgür Ersoy
Ali Turhan Çağlar
Nuri Danışman
Abstract
Amaç: Preterm erken membran rüptüründe (PPROM) ve preterm doğumda (PD) idrar yolu enfeksiyonunun olumsuz neonatal sonuçları ve doğum süresine ile arasındaki ilişkinin araştırılmasını amaçladık.
Gereç ve Yöntem: 2008-2014 yılları arasında merkezimize başvuran 1033 gebe hastayı retrospektif olarak değerlendirdik. Çalışma grupları 446 PPROM ve 587 PD hastasından oluşuyordu.
Bulgular: İdrar kültürü pozitif PPROM hastalarında transvajinal ultrasonografi ile ölçülen servikal uzunluk(OR = 0.806,) ve amniyon sıvısı indeksi (AFI), (OR = 0.961) ve idrar kültürü pozitif PD hastalarında sadece servikal uzunluk OR = 0.862 doğum süresinin yedi günden daha kısa olacağı ile ilişkili idi. Ayrıca idrar kültürü pozitif olan PPROM grubunda AFI’ nin (OR = 0.982) olumsuz neonatal sonuçlarla ilişkilendirileceğini belirledik.
Sonuç: İdrar kültürü pozitif PPROM ve PD hastalarında olumsuz neonatal sonuçları ve doğum zamanını öngörmede AFI ve servikal uzunluk da kullanılabilir.
Supporting Institution
Yok
Project Number
approval date/number:24.03.2014/39
References
- 1. Bhuvan P. Urinary Tract Infections in Pregnancy: from Symptomatic Bacteriuria to Pyelonephritis. Management of Common Problems in Obstetrics and Gynecology, 5th edition.2010; p.1312. Sobel JD, Kaye D. Urinary tract infections. In: Mandell GL, Bennett JE, Dolin R, editor(s). Mandell, Douglas and Bennett’s Principles and Practice of Infectious Diseases. 4th ed. New York: Churchill Livingstone. 1995;662–90.3. Sweet RL, Gibbs RS. Infectious diseases of the female genital tract. Philadelphia : Lippincott Williams & Wilkins. 2002;308-94. Bacak SJ, Callaghan WM, Dietz PM, Crouse C. Pregnancy-associated hospitalizations in the United States, 1999-2000. Am J Obstet Gynecol. 2005 Feb;192(2):592-7.5.Farkash E, Weintraub AY, Sergienko R, Wiznitzer A, Zlotnik A, Sheiner E. Acute antepartum pyelonephritis in pregnancy: a critical analysis of risk factors and outcomes. Eur J Obstet Gynecol Reprod Biol. 2012 May;162(1):24-7.6.Nicolle LE. Asymptomatic bacteriuria: when to screen and when to treat. Infect Dis Clin North Am. 2003 Jun;17(2):367-94.7.American College of Obstetricians and Gynecologists. ACOG Educational Bulletin No. 245. Antimicrobial therapy for obstetric patients. Int J Gynaecol Obstet. 1998;61(3):299-308.8.Gilstrap LC, Cunningham FG, Whalley PJ. Acute pyelonephritis in pregnancy: an anterospective study. Obstet Gynecol. 1981;57(4):409–13.9. Wing DA, Fassett MJ, Getahun D. Acute pyelonephritis in pregnancy: an 18 year retrospective analysis. Am J Obstet Gynecol. 2014;210(3):219.10. Berghella V, Saccone G. Cervical assessment by ultrasound for preventing preterm delivery. Cochrane Database Syst Rev. 2019 Sep 25;9:CD007235.11. Martin JA, Hamilton BE, Sutton PD, Ventura SJ, Mathews TJ, Osterman MJ. Births: final data for 2008. Natl Vital Stat Rep. 2010 Dec 8;59(1):1, 3-71.12.Cai T, Mazzoli S, Mondaini N, Meacci F, Nesi G, D'Elia C, et al.The role of asymptomatic bacteriuria in young women with recurrent urinary tract infections: to treat or not to treat? Clin Infect Dis. 2012 Sep;55(6):771-7.13.Chao TT, Bloom SL, Mitchell JS, McIntire DD, Leveno KJ.The diagnosis and natural history of false preterm labor. Obstet Gynecol. 2011 Dec;118(6):1301-8.14. American College of Obstetricians and Gynecologists. ACOG Practice bulletin no. 134: fetal growth restriction. Obstet Gynecol 2013;121(5):1122-33. 15. Romero R, Lockwood JC. Pathogenesis of Spontaneous Preterm Labor. Creasy And Resnık’s Maternal-Fetal Medıcıne: Prıncıples And Practıce, Sıxth Edıtıon. 2004;521-4316.Goldenberg RL, Culhane JF, Iams JD, Romero R. Epidemiology and causes of preterm birth. Lancet. 2008 Jan 5;371(9606):75-84.17.Smaill FM, Vazquez JC. Antibiotics for asymptomatic bacteriuria in pregnancy. Cochrane Database Syst Rev. 2015 Aug 7;(8):CD000490.18.Agger WA, Siddiqui D, Lovrich SD, Callister SM, Borgert AJ, Merkitch KW, et al. Epidemiologic factors and urogenital infections associated with preterm birth in a midwestern U.S. population. Obstet Gynecol. 2014 Nov;124(5):969-77. 19.Guerra GV, de Souza AS, da Costa BF, do Nascimento FR, Amaral Mde A, Serafim AC. Urine test to diagnose urinary tract infection in high-risk pregnant women. Rev Bras Ginecol Obstet. 2012 Nov;34(11):488-93.20.Feitosa DC, da Silva MG, de Lima Parada CM. The accuracy of simple urine tests for diagnosis of urinary tract infections in low-risk pregnant women. Rev Lat Am Enfermagem. 2009;17(4):507-13.21.Jacociunas LV, Picoli SU. Avaliação de infecçã ourin áriaemgest antes no Primeiro trimester de gravidez. Rev Bras Anal Clin. 2007;39:55-7.22.Duarte G, Marcolin AC, Gonçalves CV. Infecções urinary as nagravidez: análise dos métodos paradiagnóstico e do treatment. Rev Bras Ginecol Obstet. 2002;24:471-7.23.Iams JD, Goldenberg RL, Meis PJ, Mercer BM, Moawad A, Das A, et al. The length of the cervix and the risk of spontaneous premature delivery. National Institute of Child Health and Human Development Maternal-Fetal Medicine Unit Network. N Engl J Med. 1996 Feb 29;334(9):567-72.24.Mehra S, Amon E, Hopkins S, Gavard JA, Shyken J.Transvaginal cervical length and amniotic fluid index: can it predict delivery latency following preterm premature rupture of membranes?. Am J Obstet Gynecol. 2015 Mar;212(3):400.e1-9. 25. Lorthe E, Ancel PY, Torchin H, Kaminski M, Langer B, Subtil D, et al. Impact of Latency Duration on the Prognosis of Preterm Infants after Preterm Premature Rupture of Membranes at 24 to 32 Weeks' Gestation: A National Population-Based Cohort Study. J Pediatr. 2017 Mar;182:47-52.e2.26.Yu H, Wang X, Gao H, You Y, Xing A. Perinatal outcomes of pregnancies complicated by preterm premature rupture of the membranes before 34 weeks of gestation in a tertiary center in China: A retrospective review. Biosci Trends. Biosci Trends. 2015 Feb;9(1):35-41. 27.Cobo T, Munrós J, Ríos J, Ferreri J, Migliorelli F, Baños N, et al. Contribution of Amniotic Fluid along Gestation to the Prediction of Perinatal Mortality in Women with Early Preterm Premature Rupture of Membranes. Fetal Diagn Ther. 2018;43(2):105-112.
Evaluation of the delivery time and adverse neonatal outcomes in urinary culture-positive preterm delivery and preterm premature rupture of membranes
Year 2020,
Volume: 45 Issue: 1, 39 - 47, 31.03.2020
Sibel Özler
,
Efser Öztaş
Derya Solmaz
Başak Gümüş Güler
Ali Özgür Ersoy
Ali Turhan Çağlar
Nuri Danışman
Abstract
urpose: We aimed to investigate the relationship between adverse neonatal outcomes and the time period of labor in between urinary tract infection in preterm premature rupture of membranes (PPROM) to preterm labor (PL).
Materials and Methods: We evaluated a total number of 1033 pregnant patients who admitted to our center between 2008 and 2014, with retrospective analysis. Study groups consisted of 446 PPROM and 587 PL patients who had urine cultures.
Results: We determined cervical lengths which were measured by transvaginal ultrasonography, with OR = 0.806 and amniotic fluid index (AFI), OR = 0.961 in PPROM group, which had positive urine culture, and also cervical length OR = 0.862 in PL group which had positive urine culture and to be associated with shorter than seven days of delivery. Additionally, we determined that only the AFI, with OR= 0.982, to be associated with adverse neonatal outcomes in the PPROM group, having positive urine culture.
Conclusion: AFI and cervical length can also be used to predict adverse neonatal outcomes and time of delivery in urine culture positive PPROM and PL patients.
Project Number
approval date/number:24.03.2014/39
References
- 1. Bhuvan P. Urinary Tract Infections in Pregnancy: from Symptomatic Bacteriuria to Pyelonephritis. Management of Common Problems in Obstetrics and Gynecology, 5th edition.2010; p.1312. Sobel JD, Kaye D. Urinary tract infections. In: Mandell GL, Bennett JE, Dolin R, editor(s). Mandell, Douglas and Bennett’s Principles and Practice of Infectious Diseases. 4th ed. New York: Churchill Livingstone. 1995;662–90.3. Sweet RL, Gibbs RS. Infectious diseases of the female genital tract. Philadelphia : Lippincott Williams & Wilkins. 2002;308-94. Bacak SJ, Callaghan WM, Dietz PM, Crouse C. Pregnancy-associated hospitalizations in the United States, 1999-2000. Am J Obstet Gynecol. 2005 Feb;192(2):592-7.5.Farkash E, Weintraub AY, Sergienko R, Wiznitzer A, Zlotnik A, Sheiner E. Acute antepartum pyelonephritis in pregnancy: a critical analysis of risk factors and outcomes. Eur J Obstet Gynecol Reprod Biol. 2012 May;162(1):24-7.6.Nicolle LE. Asymptomatic bacteriuria: when to screen and when to treat. Infect Dis Clin North Am. 2003 Jun;17(2):367-94.7.American College of Obstetricians and Gynecologists. ACOG Educational Bulletin No. 245. Antimicrobial therapy for obstetric patients. Int J Gynaecol Obstet. 1998;61(3):299-308.8.Gilstrap LC, Cunningham FG, Whalley PJ. Acute pyelonephritis in pregnancy: an anterospective study. Obstet Gynecol. 1981;57(4):409–13.9. Wing DA, Fassett MJ, Getahun D. Acute pyelonephritis in pregnancy: an 18 year retrospective analysis. Am J Obstet Gynecol. 2014;210(3):219.10. Berghella V, Saccone G. Cervical assessment by ultrasound for preventing preterm delivery. Cochrane Database Syst Rev. 2019 Sep 25;9:CD007235.11. Martin JA, Hamilton BE, Sutton PD, Ventura SJ, Mathews TJ, Osterman MJ. Births: final data for 2008. Natl Vital Stat Rep. 2010 Dec 8;59(1):1, 3-71.12.Cai T, Mazzoli S, Mondaini N, Meacci F, Nesi G, D'Elia C, et al.The role of asymptomatic bacteriuria in young women with recurrent urinary tract infections: to treat or not to treat? Clin Infect Dis. 2012 Sep;55(6):771-7.13.Chao TT, Bloom SL, Mitchell JS, McIntire DD, Leveno KJ.The diagnosis and natural history of false preterm labor. Obstet Gynecol. 2011 Dec;118(6):1301-8.14. American College of Obstetricians and Gynecologists. ACOG Practice bulletin no. 134: fetal growth restriction. Obstet Gynecol 2013;121(5):1122-33. 15. Romero R, Lockwood JC. Pathogenesis of Spontaneous Preterm Labor. Creasy And Resnık’s Maternal-Fetal Medıcıne: Prıncıples And Practıce, Sıxth Edıtıon. 2004;521-4316.Goldenberg RL, Culhane JF, Iams JD, Romero R. Epidemiology and causes of preterm birth. Lancet. 2008 Jan 5;371(9606):75-84.17.Smaill FM, Vazquez JC. Antibiotics for asymptomatic bacteriuria in pregnancy. Cochrane Database Syst Rev. 2015 Aug 7;(8):CD000490.18.Agger WA, Siddiqui D, Lovrich SD, Callister SM, Borgert AJ, Merkitch KW, et al. Epidemiologic factors and urogenital infections associated with preterm birth in a midwestern U.S. population. Obstet Gynecol. 2014 Nov;124(5):969-77. 19.Guerra GV, de Souza AS, da Costa BF, do Nascimento FR, Amaral Mde A, Serafim AC. Urine test to diagnose urinary tract infection in high-risk pregnant women. Rev Bras Ginecol Obstet. 2012 Nov;34(11):488-93.20.Feitosa DC, da Silva MG, de Lima Parada CM. The accuracy of simple urine tests for diagnosis of urinary tract infections in low-risk pregnant women. Rev Lat Am Enfermagem. 2009;17(4):507-13.21.Jacociunas LV, Picoli SU. Avaliação de infecçã ourin áriaemgest antes no Primeiro trimester de gravidez. Rev Bras Anal Clin. 2007;39:55-7.22.Duarte G, Marcolin AC, Gonçalves CV. Infecções urinary as nagravidez: análise dos métodos paradiagnóstico e do treatment. Rev Bras Ginecol Obstet. 2002;24:471-7.23.Iams JD, Goldenberg RL, Meis PJ, Mercer BM, Moawad A, Das A, et al. The length of the cervix and the risk of spontaneous premature delivery. National Institute of Child Health and Human Development Maternal-Fetal Medicine Unit Network. N Engl J Med. 1996 Feb 29;334(9):567-72.24.Mehra S, Amon E, Hopkins S, Gavard JA, Shyken J.Transvaginal cervical length and amniotic fluid index: can it predict delivery latency following preterm premature rupture of membranes?. Am J Obstet Gynecol. 2015 Mar;212(3):400.e1-9. 25. Lorthe E, Ancel PY, Torchin H, Kaminski M, Langer B, Subtil D, et al. Impact of Latency Duration on the Prognosis of Preterm Infants after Preterm Premature Rupture of Membranes at 24 to 32 Weeks' Gestation: A National Population-Based Cohort Study. J Pediatr. 2017 Mar;182:47-52.e2.26.Yu H, Wang X, Gao H, You Y, Xing A. Perinatal outcomes of pregnancies complicated by preterm premature rupture of the membranes before 34 weeks of gestation in a tertiary center in China: A retrospective review. Biosci Trends. Biosci Trends. 2015 Feb;9(1):35-41. 27.Cobo T, Munrós J, Ríos J, Ferreri J, Migliorelli F, Baños N, et al. Contribution of Amniotic Fluid along Gestation to the Prediction of Perinatal Mortality in Women with Early Preterm Premature Rupture of Membranes. Fetal Diagn Ther. 2018;43(2):105-112.