Juvenil idiopatik artritli Türk çocukların büyüme parametreleri

Yıl 2020, Cilt: 45 Sayı: 2, 495 - 501, 30.06.2020

Sibel Balcı Mehmet Çalkan Semine Özdemir Dilek Doğruel Derya Altintas Rabia Miray Kisla Ekinci

https://doi.org/10.17826/cumj.675982

Cited By: 1

Öz

Amaç: Juvenil idiopatik artrit (JIA) çocukluk çağında en sık görülen romatizmal hastalıktır ve büyüme geriliği ile sonuçlanabilmektedir. Bu çalışma ile JIA’lı Türk çocuklarında büyüme parametrelerini araştırmayı amaçladık.
Gereç ve Yöntem: Juvenil idiopatik artrit tanılı 233 hastanın klinik ve laboratuvar verileri, vücut ağırlığı, boy ve vücut kitle indeksi (VKI) bilgileri hastaların tıbbi dosyalarından geriye dönük elde edildi. Büyüme verileri ve z-skorları Türk çocuklarının antropometrik referans değerlerine göre hesaplandı. Hastalara International League of Associations for Rheumatology sınıflama kriterlerine göre tanı kondu.
Bulgular: Hastaların %59,2’si (sayı, 138) kız hastaydı. Ortalama tanı yaşı 7.40±4,54 yıl ve çalışma esnasında ortalama yaş 11.20±4,45 yıldı. Ortalama ilk vizit vücut ağırlığı ve VKI z-skorları son vizit değerlere göre istatistiksel anlamlı olarak düzeldi. Ortalama ilk vizit boy z-skoru ise istatistiksel anlamlı olarak geriledi. Son vizitte kısa boy sıklığı %7,3 (sayı, 17) idi. Eritrosit çökelme hızı, C-reaktif protein düzeyleri dahil olmak üzere akut faz reaktanları son vizitte ilk vizit değerlerine kıyasla anlamlı olarak düşüktü. Son vizit büyüme parametreleri tanı yaşı, hastalık süresi, remisyon ve relaps durumu, kortikosteroid ve biyolojik ajan kullanımına göre farklılık göstermemekteydi.
Sonuç: JIA hastalarında devam eden inflamasyonun kontrol altına alınması ile vücut ağırlığı ve VKI z-skorları düzelebilir, fakat bu durum boy kısalığını önlemek için yeterli olmayabilir. 

Anahtar Kelimeler

Büyüme, çocuk, juvenile idiopatik artrit

Destekleyen Kurum

Yok

Proje Numarası

Yok

Growth parameters of Turkish children with juvenile idiopathic arthritis

Öz

Purpose: Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease in childhood which could results in growth retardation. With the present study, we aimed to investigate the growth parameters in Turkish children with JIA.
Materials and Methods: Clinical and laboratory data, weight, height, and body mass index of 233 JIA patients were retrospectively collected from medical files. Growth parameters and z-scores were calculated by anthropometric references in Turkish children. The patients were diagnosed according to the International League of Associations for Rheumatology classification criteria.
Results: The frequency of female patients was 59.2% (138). The mean age at diagnosis was 7.40±4.54 years, the mean age at the study time was 11.20±4.45 years. While mean initial visit weight and BMI z-scores were significantly improved at last visit, initial mean height z-score was significantly decreased. The frequency of short stature at last visit was 7.3% (number, 17). Acute phase reactants, including erythrocyte sedimentation rate, C-reactive protein levels were significantly lower at last visit than initial. Last visit growth parameters did not differ according age at diagnosis, disease duration and presence or absence of remission, relapses, corticosteroid usage, and biologic agent usage.
Conclusion: Suppressing ongoing inflammation in JIA patients improves both weight and BMI z-scores of those patients, however, it may be insufficient to prevent short stature. 

Anahtar Kelimeler

Growth, children, juvenile idiopathic arthritis

Proje Numarası

Yok

Kaynakça

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