Trombolitik tedavi alan ve mekanik trombektomi uygulanan akut iskemik inmeli hastalarda angio-seal kullanımının güvenirliği ve etkinliği

Year 2022, Volume: 47 Issue: 1, 183 - 190, 31.03.2022

Anıl Tanburoğlu , İsmail Karluka , Mustafa Mazıcan Çağatay Andiç

https://doi.org/10.17826/cumj.1021909

Abstract

Amaç: Bu çalışmada, köprüleyici intravenöz trombolitik tedavi uygulanıp ardından mekanik trombektomi (MT) prosedürü uygulanan hastalarda, femoral arter giriş yerinin, Angio-Seal Vasküler Kapatma Cihazı kullanılarak kapatılmasının etkinliğini ve güvenirliğini değerlendirilmesi amaçlanmıştır..
Gereç ve Yöntem: Bu retrospektif, gözlemsel çalışma, Eylül 2018- Eylül 2021 tarihleri arasında akut iskemik inme nedeniyle başvurmuş, köprüleyici tPA (doku plazminojen aktivatörü) sonrasında mekanik trombektomi işlemi gerçekleştirilmiş ve femoral arter giriş yerleri Angio-Seal ile kapatılan toplam 97 hasta çalışmaya dahil edilerek gerçekleştirilmiştir. Temel demografik veriler, eşlik eden risk faktörleri, major ve minör komplikasyon oranlarının, kategorik değişkenlere ait frekans dağılımları ile nicel verilere ait tanımlayıcı istatistikler hesaplanarak kaydedilmiştir.
Bulgular: Hastaların %96,9'unda major komplikasyon ve %97,9'unda minör komplikasyon olmadığı bulunmuştur. Tüm hastalarda kasık bölgesinde başarılı hemostaz sağlanmıştır. Major komplikasyonlar, 1 (%1) psödo-anevrizma, 1 (%1) kasık girim bölgesinde enfeksiyon, 1 (%1) Angio-Seal yerleştirmede başarısızlık olarak kaydedilmiştir. 6 Fr (French) Angio-Seal kullanılanlarda %98,2’sinde ve 8 Fr Angio-Seal kullanılanların %95,1’inde majör komplikasyon görülmemiştir.
Sonuç: Köprüleyici tPA kullanılan ve MT işlemi gerçekleştirilen akut iskemik inmeli hastalarda, kasık hemostazının sağlanmasında Angio-Seal kullanımı, geniş çaplı arteriotomilerde dahil olmak üzere etkili ve güvenli bir yöntemdir.

Keywords

Trombolitik Tedavi, İnme, Angio-Seal

Supporting Institution

Bu çalışma Başkent Üniversitesi Tıp ve Sağlık Bilimleri Araştırma Kurulu tarafından onaylanmış ve desteklenmiştir.

Project Number

KA21/452

Safety and efficacy of angio-seal use in patients with acute ischemic stroke who received thrombolytic therapy and underwent mechanical thrombectomy

Abstract

Purpose: This study aims to evaluate the efficacy and safety of closure of the femoral artery access site using the Angio-Seal Vascular Closure Device in patients who underwent bridging intravenous thrombolytic therapy and subsequent mechanical thrombectomy (MT).
Materials and Methods: The retrospective, observational study was performed in patients who were diagnosed with acute ischemic stroke and treated with MT after bridging IVT between September 2018 and September 2021. A total of 97 patients whose femoral artery access sites were closed with Angio-Seal after the procedure was performed were included in the study. Primary demographic data, accompanying risk factors, major and minor complication rates, frequency distributions of categorical variables, and descriptive statistics of quantitative data were calculated and recorded.
Results: It was found that 96.9% of the patients did not have major complications, where 97.9% did not have minor complications either. Successful hemostasis was achieved in the groin region in all patients. Major complications observed were recorded as follows: 1 (1%) pseudo-aneurysm, 1 (%) inguinal incision site infection, and 1 (1%) Angio-Seal placement failure. No major complications were observed in 98.2% of those using 6 Fr (French) Angio-Seal and 95.1% of those using 8 Fr Angio-Seal.
Conclusion: The findings of the study indicate that Angio-Seal is an effective and safe method for providing groin hemostasis in patients with acute ischemic stroke

Keywords

Thrombolytic therapy, stroke, angio-seal

Project Number

KA21/452

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