Research Article

In-vitro antioxidant and in-silico wound healing activity of Quercus infectoria dry extract

Volume: 7 Number: 1 July 6, 2024
EN

In-vitro antioxidant and in-silico wound healing activity of Quercus infectoria dry extract

Abstract

In the present study we were interested in the healing activity of Quercus infectoria gall extract. We started by preparing the extract by two methods. The polyphenol and tannin content was then determined. The antioxidant activity of the extract was evaluated in-vitro using DPPH radical scavenging assay. The last part of this study concerns the study of the healing activity in silico by molecular docking assisted by the Shrödinger program and this via the inhibition of GSK3-β, an enzyme involved among others in the healing process.

Keywords

References

  1. 1. Shrestha, S., Kaushik, V. S., Eshwarappa, R. S. B., Subaramaihha, S. R., Ramanna, L. M., & Lakkappa, D. B. (2014). Pharmacognostic studies of insect gall of Quercus infectoria Olivier (Fagaceae). Asian Pacific Journal of Tropical Biomedicine, 4(1), 35-39.
  2. 2. Fabre, B., Poitier, A., Fontanel, D., Duvnjak, P., (1992). Brevet européen. Extraits de Noix d'Alep, leur préparation et leurs applications. 0496173 A1, 2-7.
  3. 3. Elham, A., Arken, M., Kalimanjan, G., Arkin, A., & Iminjan, M. (2021). A review of the phytochemical, pharmacological, pharmacokinetic, and toxicological evaluation of Quercus Infectoria galls. Journal of Ethnopharmacology, 273, 113592.
  4. 4. Kaur, G., Hamid, H., Ali, A., Alam, M. S., & Athar, M. (2004). Antiinflammatory evaluation of alcoholic extract of galls of Quercus infectoria. Journal of ethnopharmacology, 90(2-3), 285-292.
  5. 5. Kuo, C. L., Lai, K. C., Ma, Y. S., Weng, S. W., Lin, J. P., & Chung, J. G. (2014). Gallic acid inhibits migration and invasion of SCC 4 human oral cancer cells through actions of NF κB, Ras and matrix metalloproteinase-2 and-9. Oncology reports, 32(1), 355-361.
  6. 6. Harish, B. G., Krishna, V., Kumar, H. S., Ahamed, B. K., Sharath, R., & Swamy, H. K. (2008). Wound healing activity and docking of glycogen-synthase-kinase-3-β-protein with isolated triterpenoid lupeol in rats. Phytomedicine, 15(9), 763-767.
  7. 7. Lastra Valdés, H., Rodríguez Leyes, E., Ponce de León Rego, H., & González Sanabia, M. L. (2000). Método analítico para la cuantificación de taninos en el extracto acuoso de romerillo. Revista cubana de plantas medicinales, 5(1), 17-22.
  8. 8. Sánchez‐Moreno, C., Larrauri, J. A., & Saura‐Calixto, F. (1998). A procedure to measure the antiradical efficiency of polyphenols. Journal of the Science of Food and Agriculture, 76(2), 270-276.

Details

Primary Language

English

Subjects

Plant Biochemistry, Pharmacognosy

Journal Section

Research Article

Early Pub Date

July 6, 2024

Publication Date

July 6, 2024

Submission Date

May 24, 2024

Acceptance Date

June 28, 2024

Published in Issue

Year 2024 Volume: 7 Number: 1

APA
Benlazar, M. I., & Merzoug, S. (2024). In-vitro antioxidant and in-silico wound healing activity of Quercus infectoria dry extract. Current Perspectives on Medicinal and Aromatic Plants, 7(1), 41-47. https://doi.org/10.38093/cupmap.1488652
AMA
1.Benlazar MI, Merzoug S. In-vitro antioxidant and in-silico wound healing activity of Quercus infectoria dry extract. CUPMAP. 2024;7(1):41-47. doi:10.38093/cupmap.1488652
Chicago
Benlazar, Mohammed Ismail, and Soumia Merzoug. 2024. “In-Vitro Antioxidant and In-Silico Wound Healing Activity of Quercus Infectoria Dry Extract”. Current Perspectives on Medicinal and Aromatic Plants 7 (1): 41-47. https://doi.org/10.38093/cupmap.1488652.
EndNote
Benlazar MI, Merzoug S (July 1, 2024) In-vitro antioxidant and in-silico wound healing activity of Quercus infectoria dry extract. Current Perspectives on Medicinal and Aromatic Plants 7 1 41–47.
IEEE
[1]M. I. Benlazar and S. Merzoug, “In-vitro antioxidant and in-silico wound healing activity of Quercus infectoria dry extract”, CUPMAP, vol. 7, no. 1, pp. 41–47, July 2024, doi: 10.38093/cupmap.1488652.
ISNAD
Benlazar, Mohammed Ismail - Merzoug, Soumia. “In-Vitro Antioxidant and In-Silico Wound Healing Activity of Quercus Infectoria Dry Extract”. Current Perspectives on Medicinal and Aromatic Plants 7/1 (July 1, 2024): 41-47. https://doi.org/10.38093/cupmap.1488652.
JAMA
1.Benlazar MI, Merzoug S. In-vitro antioxidant and in-silico wound healing activity of Quercus infectoria dry extract. CUPMAP. 2024;7:41–47.
MLA
Benlazar, Mohammed Ismail, and Soumia Merzoug. “In-Vitro Antioxidant and In-Silico Wound Healing Activity of Quercus Infectoria Dry Extract”. Current Perspectives on Medicinal and Aromatic Plants, vol. 7, no. 1, July 2024, pp. 41-47, doi:10.38093/cupmap.1488652.
Vancouver
1.Mohammed Ismail Benlazar, Soumia Merzoug. In-vitro antioxidant and in-silico wound healing activity of Quercus infectoria dry extract. CUPMAP. 2024 Jul. 1;7(1):41-7. doi:10.38093/cupmap.1488652

Cited By

-------------------------------------------------------------------------------------------------------------------------------

csm_neu_ezb_logo_670e8bf80b.jpg  Google_Scholar_logo_2015.PNG index_copernicus.jpg wclogo_block.png  logo.png  

Akademia_sosyal_bilimler_indeksi_logosu.gif  wide.png424-4243430_reviewers-for-these-journals-can-track-verify-and.png  orcid_logo.png?version=1&modificationDate=1473862307894&api=v2  1*mvsP194Golg0Dmo2rjJ-oQ.jpeg  aji.png citefactor-e1553074491226.png    logo1.jpg  semantci.png

-------------------------------------------------------------------------------------------------------------------------

88x31.png CUPMAP Journal is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

-----------------------------------------------------------------------------------------------------------------------------------------

Open_Access_PLoS.svg

This is an open access journal which means that all content is freely available without charge to the user or his/her institution. Users are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles, or  use them for any other lawful purpose, without asking prior permission from the publisher or the author. This is in accordance with the BOAI definition of open access.