The Efficiency of Bioapifit® Wound Care Ointment in the Treatment of Diabetic Foot Ulcers

Yıl 2019, Cilt: 2 Sayı: 2, 133 - 137, 26.12.2019

Višnja Oreščanin Zrinka Mihalic Josipa Rodic štefica Findri Gustek

https://doi.org/10.38093/cupmap.604224

Öz

Objective/Purpose: The objective of this study was efficacy and safety assessment of
Bioapifit® wound care ointment consisted of honey, Cera flava, glycerin, the oil macerates of astringent and soothing
herbs  combined with essential oils for
the treatment of diabetic neuropathic foot ulcers of grade II. Materials and methods: 50 patients with
Wagner grade II diabetic foot ulcers were randomized into experimental and
control group (25 patients each). The experimental group was treated 28 days
with Bioapifit® wound care ointment applied on the wound after cleaning with
povidone iodine once a day and covered with sterile gauze and bandage during
the whole course of the study. The control group wounds  were cleaned with povidone iodine once a day
and covered with sterile gauze and bandage during the whole course of the study
without further treatment. The ulcers surface area was measured at baseline and
after 14 and 28 days of the treatment. Results:
In the end of the treatment the mean values and standard deviation of the
surface area in the experimental group dropped from 8.27±6.1 cm² to
0.74±0.21 cm² for males and from 9.01±5.9 cm² to
0.81±0.11 cm² for females. Slight, insignificant decrease was also
observed in the control population (up to 25%). No side-effects were observed
during the course of the study. Conclusion/Discussion:
Four weeks treatment with Bioapifit® wound care ointment resulted in complete
wound closure in 84% of the patients and 91% reduction in the wound surface
area in the rest of them.

Anahtar Kelimeler

diabetic foot ulcers, honey, beeswax, herbal macerate, essential oils

Kaynakça

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