Sürü Koruyan ve Barınakta Tutulan Kangal Çoban Köpeklerinde Serum ve Tükürük CK, AST ve LDH Seviyelerinin Araştırılması

Yıl 2022, Cilt: 7 Sayı: 3, 200 - 204, 30.12.2022

Mustafa Koçkaya Mehmet Ekici

https://doi.org/10.51754/cusbed.1163814

Öz

Sürü koruma görevi yapan Kangal çoban köpeklerinin günlük fiziksel aktivitelerinin barınaklarda yaşayanlara göre daha fazla olduğu bilinen bir gerçektir. Fiziksel aktivite ve kas metabolizması arasındaki ilişki iyi bilinmektedir. Ancak literatürde sürüleri koruyan ve barınaklarda yaşayan Kangal çoban köpeklerinin kas metabolizmasındaki farklılıkları ortaya koyan bir çalışma bulunmamaktadır. Bu çalışmanın amacı, sürü koruma görevi yapan Kangal çoban köpekleri ile barınakta yaşayan Kangallar arasındaki kas metabolizması farklılıklarının araştırılmasıdır. Çalışmada sürü koruma görevi yapan ve barınakta tutulan genç Kangal köpekleri erkek ve dişi gruplarına ayrıldı toplam 32 adet köpek 4 gruba ayrıldı (n=8/grup). Serum ve tükürük örneklerinden kas metabolizması ile ilgili kreatin kinaz (CK), laktat dehidrojenaz (LDH) ve aspartat aminotransferaz (AST) parametreleri otoanalizör ile analiz edildi. Serum CK düzeyleri barınak köpeklerinde sürü koruma köpeklerine göre daha düşük bulunurken, en yüksek değer sürü koruyan dişilerde gözlendi. Tükürük CK seviyeleri barınak ve sürü koruyan erkek köpeklerde en yüksek, sürü koruyan dişi köpeklerde en düşüktü. Serum AST değeri en yüksek barınakta yaşayan dişilerde, en düşük serum AST değeri ise barınaktaki erkek köpeklerde tespit edildi. Ancak tükürük AST düzeyleri barınaktaki erkek ve dişi köpeklerde ve sürü koruyan erkeklerde yüksek olmasına rağmen sürü koruyan dişi köpeklerde ise düşüktü. Serum LDH düzeyleri barınaktaki dişilerde, sürüdeki erkek ve dişilerde yüksek, barınaktaki erkek köpeklerde ise düşüktü. Tükürük LDH düzeyleri barınak köpeklerinde en yüksek, sürü koruyan dişilerde en düşüktü. Bu çalışmada ilk kez Kangal çoban köpeklerinde serum ve tükürük örneklerinde kas metabolizması ile ilgili değişkenler (CK, AST ve LDH) araştırılmıştır.

Anahtar Kelimeler

Aspartate Aminotransferase, Creatine Kinase, Kangal Çoban Köpeği, Kas Metabolizması, Lactate Dehydrogenase

Investigation of Serum and Saliva CK, AST and LDH Levels in Herd Guards and Shelter Kangal Shepherd Dogs

Öz

It is a fact that Kangal shepherd dogs, who serve as herd guards, have more daily physical activity than those living in the shelter. The relationship between physical activity and muscle metabolism is well known. However, no study has been found in the literature that reveals differences in muscle metabolism among Kangal shepherd dogs that protect their herd and live in shelters. The aim of this study is to investigate the muscle metabolism differences between the herd guards and those living in the shelter in Kangal shepherd dogs. In the study, a total of 32 young male and female Kangal dogs that guard the herd and live in the shelter were randomly divided into four equal groups (n=8/group). From serum and saliva samples, creatine kinase (CK), lactate dehydrogenase (LDH), and aspartate aminotransferase (AST) parameters related to muscle metabolism were analyzed with an autoanalyzer. Serum CK levels were lower in shelter dogs than in herd dogs, while the highest value was observed in females in the herd. Salivary CK levels were highest in the shelter and herd male dogs and lowest in herd female dogs. The highest serum AST value was seen in females living in the shelter, while the lowest was seen in sheltered males. However, salivary AST levels were higher in males and females in the shelter and males in the herd than females in the herd. Serum LDH levels were higher in females in the shelter and males and females in the herd than males in the shelter. Saliva LDH levels were highest in the shelter and lowest in females in the herd. In this study, muscle metabolism-related variables (CK, AST, and LDH) were investigated for the first time in Kangal sheepdogs from serum and saliva samples.

Anahtar Kelimeler

Aspartate Aminotransferase, Creatine Kinase, Kangal Shepherd Dogs, Lactate Dehydrogenase, Muscle Metabolism

Kaynakça

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