The Relationship Between Lipid Levels And Bone Mineral Density in Postmenopausal Women

Yıl 2010, Cilt: 12 Sayı: 2, 30 - 35, 01.07.2010

Yalkın Çalık Selma Yazıcı Ersun Baş Safinaz Ataoglu

Öz

Objective: The aim of this study is to investigate the relationship between lipid levels and bonemineral density in postmenopausal womenMethods: We studied 276 postmenopausal women aged 45- 65 years (mean 54 years) whoattended Duzce University faculty of medicine physical medicine and rehabilitation polyclinic.Bone mineral density in the lumbar spine and femur neck were measured by dual energy X-rayabsorptiometry. Serum cholesterol, lipoproteins and triglyceride were assessed on a bloodsample obtained after a 12-hour fast. All participants were given a questionnaire to answer onvarious risk factors for osteoporosis. Participants who reported the use of hormone replacementtherapy and lipid lowering therapy were excluded. Statistically significant associations werefound by SPSS 11.0 and p0,05)higher body mass index is associated with higher bone mineral density at femur neck and lumbarspine (both p values

Anahtar Kelimeler

postmenopausal women, plasma lipid levels, bone mineral density

Postmenopozal Kadınlarda Lipid Düzeyleri Ve Kemik Mineral Yoğunluğu Arasındaki İlişki

Öz

Amaç: Bu çalışmanın amacı postmenapozal kadınlarda lipid düzeyleri ile kemik mineral yoğunluğu arasındaki ilişkiyi araştırmaktır. Yöntem: Çalışmaya Düzce Üniversitesi Tıp Fakültesi Fiziksel Tıp ve Rehabilitasyon AD. polikliniğine başvuran 45-65 yaşları arası (ortalama yaş 54) 276 postmenopozal kadın alındı. Lomber vertebra ve femur boynu kemik mineral yoğunlukları dual enerji X ray absorbsiyometre ile, 12 saat süren açlık sonrası alınan kan örneklerinden serum total kolesterol, lipoproteinler ve trigliserid ölçüldü Çalışmaya hormon replasman ve lipid düzeyi düşürücü tedavi alanlar dahil edilmedi. Çalışmaya alınan tüm kadınlara osteoporoz sorgulama formu dolduruldu. Bulgular: Serum lipoproteinleri, total kolesterol ve trigliserid ile femur boynu ve lomber vertebra kemik mineral yoğunlukları arasında anlamlılık bulunamadı (p>0,05). Yüksek vücut kitle indeksi ile femur boynu ve lomber vertebrada yüksek kemik mineral yoğunluğu istatistiksel olarak anlamlı bulundu (p

Anahtar Kelimeler

postmenopozal kadın, plazma lipid düzeyleri, kemik mineral yoğunluğu

Kaynakça

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