A case of Acute Disseminated Encephalomyelitis in a Pediatric Patient Presenting with Isolated Bilateral Optic Neuritis

Yıl 2014, Cilt: 16 Sayı: 2, 49 - 51, 01.07.2014

Derya Türeli Mine Aslan Gazanfer Ekinci Ahmet Aslan

Öz

Acute disseminated encephalomyelitis (ADEM) is an inflammatory disease which ischaracterized by demyelination of the central nervous system. Optic neuritis is the most commonophthalmic manifestation of the disease. Various neurological symptoms can be seen accordingto the extent of the disease. Because of the increased risk of multiple sclerosis development;diagnosis, treatment and follow-up of ADEM is essential. Our aim was to present a case ofpediatric ADEM, which presented with optic neuritis alone in the light of current literature

Anahtar Kelimeler

Acute disseminated encephalomyelitis, childhood, optic neuritis

İZOLE BİLATERAL OPTİK NÖRİT İLE PREZENTE OLAN PEDİYATRİK AKUT DİSSEMİNE ENSEFALOMYELİT OLGUSU

Öz

Akut dissemine ensefalomyelit (ADEM) santral sinir sisteminin demiyelinizasyonu ilekarakterize, enflamatuar bir hastalığıdır. En sık izlenen oftalmik bulgusu optik nörittir. Hastalığınyaygınlığına göre değişik nörolojik bulgular izlenebilir. Multipl skleroz gelişme riskini arttığıiçin ADEM tanısı, tedavisi ve takibi önemlidir. Burada başka nörolojik bulgu olmadan sadeceoptik nörit ile prezente olan pediatrik ADEM olgusunu güncel literatür eşliğinde sunmayıamaçladık

Anahtar Kelimeler

Akut dissemine ensefalomyelit, çocukluk çağı, optik nörit

Kaynakça

• Şahin S, Uysal S. Akut dissemine ensefalomiyelit (ADEM). Türk Pediatri Arşivi. 2005;40:199-203.
• Sim JE, Lee JB, Cho YN, Suh SH, Kim JK, Lee KY.A case of acute disseminated encephalomyelitis associated with hepatitis C virus infection. Yonsei Med J. 2012;53:856-858.
• Stonehouse M, Gupte G, Wassmer E, Whitehouse WP. Acute disseminated encephalomyelitis: recognition in the hands of general paediatricians. Arch Dis Child. 200;88:122-124.
• Apak RA, Köse G, Anlar B, Turanli G, Toplaoğlu H, Ozdirim E. Acute disseminated encephalomyelitis in childhood: report of 10 cases. J Child Neurol. 1999;14:198-201.
• Katzman GL: ADEM. In: Osborn A (ed): Diagnostic İmaging: Brain. Manitoba. Amirsys. pp: I/8/78-80, 2004.
• Alper G, Wang L. Demyelinating optic neuritis in children. J Child Neurol. 2009;24:45-48.
• Krupp LB, Banwell B, TenembaumS; International Pediatric MS Study Group. Consensus definitions proposed for pediatric multiple sclerosis and related disorders. Neurology. 2007;17;68(16 Suppl 2):S7-12.
• Sapuan S, Basri H. Acute disseminated encephalomyelitis (ADEM) presenting with bilateral optic neuritis. Malays J Med Sci. 2007;14:71-74.
• Kabakuş N, Kurt ANÇ. Akut dissemine ensefalomyelit: Klinik seri. Fırat Tıp Dergisi. 2005;10(3):127-131.
• Costanzo MD, Camarca ME, Colella MG, Buttaro G, Elefante A, Canani RB. Acute disseminated encephalomyelitis presenting as fever of unknown origin: case report. BMC Pediatr. 2011 10;11:103.
• R K Garg. Acute disseminated encephalomyelitis. Postgrad Med J. 2003;79:11–17.
• Nishikawa M, Ichiyama T, Hayashi T, Ouchi K, Furukawa S. Intravenous immunoglobulin therapy in acute disseminated encephalopathy. Paed Neurology. 1999;21:583-586.
• Toker E, Yenice O, Yilmaz Y. Isolated bilateral optic neuropathy in acute disseminated encephalomyelitis. J Ped Ophth Strabismus. 2003;40;232-235.