Clinical Research

Classification of Knee X-rays That Can Be Diagnosed Radiographically Using Deep Learning and Machine Learning Methods

Volume: 13 Number: 3 July 31, 2025
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Classification of Knee X-rays That Can Be Diagnosed Radiographically Using Deep Learning and Machine Learning Methods

Abstract

The aim of this study is to classify knee osteoarthritis, synovial chondromatosis, Osgood-Schlatter disease, os fabella pathologies that can be diagnosed with plain knee X-rays, and normal knee radiographs with deep learning and machine learning methods. This study was performed on 540 knee osteoarthritis, 151 Osgood_Schlatter disease, 191 knee chondromatosis, 152 os fabella and 523 normal knee X-ray images. First, classification was performed with the VGG-16 network, which is a pre-trained deep learning model. Then, the features extracted with the VGG-16 convolution layer were classified with random forest, support vector machines, logistic regression and decision tree machine learning algorithms. With VGG-16 model, 95.3% accuracy, 95.1% sensitivity, 98.7% specificity, 96.8% precision, and 95.9% F1 score results were obtained. In classifying the features extracted from the VGG- 16 convolution layer with machine learning algorithms, 98.2% accuracy, 99.0% sensitivity, 98.9% specificity, 98.2% precision and 98.5% F1 score results were obtained with the logistic regression classifier. In this study, which was conducted to classify radiographically detectable knee pathologies, successful results were obtained with the VGG-16 network. The features extracted from the convolution layer of the VGG-16 model were reclassified with machine learning algorithms, logistic regression, support vector machines and random forest classifiers, and improvements in performance metrics were obtained compared to the VGG-16 model. With this proposed method, the performance of deep learning models can be further improved.

Keywords

Supporting Institution

Funding None

Ethical Statement

ETHICS APPROVAL: An ethical approval certificate was obtained from the local ethic commitee, Ankara Bilkent City Hospital, Clinical Research Ethics Committee No. 1, date : 20.04.2022, no : E1-22-2420

References

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Details

Primary Language

English

Subjects

Deep Learning

Journal Section

Clinical Research

Publication Date

July 31, 2025

Submission Date

January 24, 2025

Acceptance Date

May 26, 2025

Published in Issue

Year 2025 Volume: 13 Number: 3

APA
Üreten, K., Duran, S., Maraş, Y., Atalar, E., Orhan, K., & Maraş, H. H. (2025). Classification of Knee X-rays That Can Be Diagnosed Radiographically Using Deep Learning and Machine Learning Methods. Duzce University Journal of Science and Technology, 13(3), 1297-1308. https://doi.org/10.29130/dubited.1626406
AMA
1.Üreten K, Duran S, Maraş Y, Atalar E, Orhan K, Maraş HH. Classification of Knee X-rays That Can Be Diagnosed Radiographically Using Deep Learning and Machine Learning Methods. DUBİTED. 2025;13(3):1297-1308. doi:10.29130/dubited.1626406
Chicago
Üreten, Kemal, Semra Duran, Yüksel Maraş, Ebru Atalar, Kevser Orhan, and Hadi Hakan Maraş. 2025. “Classification of Knee X-Rays That Can Be Diagnosed Radiographically Using Deep Learning and Machine Learning Methods”. Duzce University Journal of Science and Technology 13 (3): 1297-1308. https://doi.org/10.29130/dubited.1626406.
EndNote
Üreten K, Duran S, Maraş Y, Atalar E, Orhan K, Maraş HH (July 1, 2025) Classification of Knee X-rays That Can Be Diagnosed Radiographically Using Deep Learning and Machine Learning Methods. Duzce University Journal of Science and Technology 13 3 1297–1308.
IEEE
[1]K. Üreten, S. Duran, Y. Maraş, E. Atalar, K. Orhan, and H. H. Maraş, “Classification of Knee X-rays That Can Be Diagnosed Radiographically Using Deep Learning and Machine Learning Methods”, DUBİTED, vol. 13, no. 3, pp. 1297–1308, July 2025, doi: 10.29130/dubited.1626406.
ISNAD
Üreten, Kemal - Duran, Semra - Maraş, Yüksel - Atalar, Ebru - Orhan, Kevser - Maraş, Hadi Hakan. “Classification of Knee X-Rays That Can Be Diagnosed Radiographically Using Deep Learning and Machine Learning Methods”. Duzce University Journal of Science and Technology 13/3 (July 1, 2025): 1297-1308. https://doi.org/10.29130/dubited.1626406.
JAMA
1.Üreten K, Duran S, Maraş Y, Atalar E, Orhan K, Maraş HH. Classification of Knee X-rays That Can Be Diagnosed Radiographically Using Deep Learning and Machine Learning Methods. DUBİTED. 2025;13:1297–1308.
MLA
Üreten, Kemal, et al. “Classification of Knee X-Rays That Can Be Diagnosed Radiographically Using Deep Learning and Machine Learning Methods”. Duzce University Journal of Science and Technology, vol. 13, no. 3, July 2025, pp. 1297-08, doi:10.29130/dubited.1626406.
Vancouver
1.Kemal Üreten, Semra Duran, Yüksel Maraş, Ebru Atalar, Kevser Orhan, Hadi Hakan Maraş. Classification of Knee X-rays That Can Be Diagnosed Radiographically Using Deep Learning and Machine Learning Methods. DUBİTED. 2025 Jul. 1;13(3):1297-308. doi:10.29130/dubited.1626406