Research Article

Automated Apical Periodontitis Detection on Panoramic Radiographs: Comparative Analysis of Modern Object Detectors and the Effect of Data Augmentation

Volume: 14 Number: 4 October 23, 2026
TR EN

Automated Apical Periodontitis Detection on Panoramic Radiographs: Comparative Analysis of Modern Object Detectors and the Effect of Data Augmentation

Abstract

Detecting apical periodontitis lesions on panoramic radiographs (PR) is challenging because lesions may be subtle and affected by anatomic superimposition, variable contrast, and restorative artifacts. This study compared five modern object detectors from the YOLOv8, YOLOv11, and RT-DETR families and quantified the effect of training data augmentation using a publicly available dataset. All final comparisons used a standardized input size of 1024×1024 pixels and batch size of 16. Each model–regime combination was evaluated over three independent random seeds, and performance was assessed on a fixed held-out test split comprising 393 images with 693 annotated lesions. Augmentation improved F1-score and AP-based detection performance across all architectures. Among augmented models, RT-DETR-l achieved the highest mean F1-score (0.685 ± 0.011; 95% CI: 0.657–0.714), while YOLOv11-l achieved the highest mean AP@0.50 (0.738 ± 0.018; 95% CI: 0.694–0.782) and AP@0.50:0.95 (0.352 ± 0.012; 95% CI: 0.323–0.380). The largest absolute F1 improvement was observed for YOLOv11-s (ΔF1 = +0.141). Two-sided paired comparisons with Holm correction showed significant augmentation-related F1 improvements for all five detectors. Region-wise failure analysis of augmented YOLOv11-l showed a higher false-negative rate in the maxilla (57.6%) than in the mandible (30.0%). These findings demonstrate that augmentation consistently improves PR-based apical lesion detection under repeated-seed evaluation and support the use of modern detectors as assistive second-reader tools, while final clinical decisions remain with the dentist.

Keywords

Apical periodontitis, Panoramic radiography, Object detection, Data augmentation, Clinical decision support

Supporting Institution

This research received no external funding.

Ethical Statement

This study used secondary analysis of a publicly available dataset and did not involve new participant recruitment, data collection, or intervention. Ethical approval for the original data collection was obtained by the dataset providers from the Institutional Review Board of Hanoi Medical University (HMUIRB463; August 3, 2021).

Thanks

The authors do not wish to acknowledge any individual or institution.

References

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APA
Duru, A., & Karayürek, F. (2026). Automated Apical Periodontitis Detection on Panoramic Radiographs: Comparative Analysis of Modern Object Detectors and the Effect of Data Augmentation. Duzce University Journal of Science and Technology, 14(4), 1138-1151. https://doi.org/10.29130/dubited.1906306
AMA
1.Duru A, Karayürek F. Automated Apical Periodontitis Detection on Panoramic Radiographs: Comparative Analysis of Modern Object Detectors and the Effect of Data Augmentation. DUBİTED. 2026;14(4):1138-1151. doi:10.29130/dubited.1906306
Chicago
Duru, Anday, and Fatih Karayürek. 2026. “Automated Apical Periodontitis Detection on Panoramic Radiographs: Comparative Analysis of Modern Object Detectors and the Effect of Data Augmentation”. Duzce University Journal of Science and Technology 14 (4): 1138-51. https://doi.org/10.29130/dubited.1906306.
EndNote
Duru A, Karayürek F (October 1, 2026) Automated Apical Periodontitis Detection on Panoramic Radiographs: Comparative Analysis of Modern Object Detectors and the Effect of Data Augmentation. Duzce University Journal of Science and Technology 14 4 1138–1151.
IEEE
[1]A. Duru and F. Karayürek, “Automated Apical Periodontitis Detection on Panoramic Radiographs: Comparative Analysis of Modern Object Detectors and the Effect of Data Augmentation”, DUBİTED, vol. 14, no. 4, pp. 1138–1151, Oct. 2026, doi: 10.29130/dubited.1906306.
ISNAD
Duru, Anday - Karayürek, Fatih. “Automated Apical Periodontitis Detection on Panoramic Radiographs: Comparative Analysis of Modern Object Detectors and the Effect of Data Augmentation”. Duzce University Journal of Science and Technology 14/4 (October 1, 2026): 1138-1151. https://doi.org/10.29130/dubited.1906306.
JAMA
1.Duru A, Karayürek F. Automated Apical Periodontitis Detection on Panoramic Radiographs: Comparative Analysis of Modern Object Detectors and the Effect of Data Augmentation. DUBİTED. 2026;14:1138–1151.
MLA
Duru, Anday, and Fatih Karayürek. “Automated Apical Periodontitis Detection on Panoramic Radiographs: Comparative Analysis of Modern Object Detectors and the Effect of Data Augmentation”. Duzce University Journal of Science and Technology, vol. 14, no. 4, Oct. 2026, pp. 1138-51, doi:10.29130/dubited.1906306.
Vancouver
1.Anday Duru, Fatih Karayürek. Automated Apical Periodontitis Detection on Panoramic Radiographs: Comparative Analysis of Modern Object Detectors and the Effect of Data Augmentation. DUBİTED. 2026 Oct. 1;14(4):1138-51. doi:10.29130/dubited.1906306