Chemical Composition of Lamium purpureum L. and Determination of Anticancer Activity of Its Essential Oil on Melanoma

Ayşegül Akkoyunlu; Gorkem Dulger

doi:10.29130/dubited.553793

EN TR

Chemical Composition of Lamium purpureum L. and Determination of Anticancer Activity of Its Essential Oil on Melanoma

Abstract

The current study aimed to evaluate Lamium purpureum L. in terms of its chemical composition and the potential of its essential oil for anticancer activity. The profiling analysis of its chemical composition was carried out via GC-MS. For this purpose, the ethanol extract was subjected to GC-MS analysis to determine chemical compounds. To obtain essential oil, steam distillation of the whole plant (aerial, leaf, stem) was carried out in a Clevenger apparatus. The anticancer activitiy was determined via MTT assay. We observed that the maximum cell death was 14% at 50 μg/mL concentration. As a result of GC-MS analysis, palmitic acid, 7-tetradecenal, octadecadienoic acid, acetic acid, ethyl 9,12,15-octadecatrienoate, hexatriacontane, stearate and benzyl benzoate were identified as major components. We determined that the essential oil of L. purpureum L. had essential compounds which showed cytotoxic activities.

Keywords

GC-MS analysis,Anticancer activity,MTT,Essential oil,Lamium purpureum L.

References

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Details

Primary Language

English

Subjects

Engineering

Journal Section

Research Article

Authors

Ayşegül Akkoyunlu ^*
0000-0002-3663-7412
Türkiye

Gorkem Dulger
0000-0002-1506-1549
Türkiye

Publication Date

July 31, 2019

Submission Date

April 15, 2019

Acceptance Date

June 21, 2019

Published in Issue

Year 2019 Volume: 7 Number: 3

DOI

https://doi.org/10.29130/dubited.553793

IZ

https://izlik.org/JA77LE29YP

APA

Akkoyunlu, A., & Dulger, G. (2019). Chemical Composition of Lamium purpureum L. and Determination of Anticancer Activity of Its Essential Oil on Melanoma. Duzce University Journal of Science and Technology, 7(3), 1755-1763. https://doi.org/10.29130/dubited.553793

AMA

1.Akkoyunlu A, Dulger G. Chemical Composition of Lamium purpureum L. and Determination of Anticancer Activity of Its Essential Oil on Melanoma. DUBİTED. 2019;7(3):1755-1763. doi:10.29130/dubited.553793

Chicago

Akkoyunlu, Ayşegül, and Gorkem Dulger. 2019. “Chemical Composition of Lamium Purpureum L. And Determination of Anticancer Activity of Its Essential Oil on Melanoma”. Duzce University Journal of Science and Technology 7 (3): 1755-63. https://doi.org/10.29130/dubited.553793.

EndNote

Akkoyunlu A, Dulger G (July 1, 2019) Chemical Composition of Lamium purpureum L. and Determination of Anticancer Activity of Its Essential Oil on Melanoma. Duzce University Journal of Science and Technology 7 3 1755–1763.

IEEE

[1]A. Akkoyunlu and G. Dulger, “Chemical Composition of Lamium purpureum L. and Determination of Anticancer Activity of Its Essential Oil on Melanoma”, DUBİTED, vol. 7, no. 3, pp. 1755–1763, July 2019, doi: 10.29130/dubited.553793.

ISNAD

Akkoyunlu, Ayşegül - Dulger, Gorkem. “Chemical Composition of Lamium Purpureum L. And Determination of Anticancer Activity of Its Essential Oil on Melanoma”. Duzce University Journal of Science and Technology 7/3 (July 1, 2019): 1755-1763. https://doi.org/10.29130/dubited.553793.

JAMA

1.Akkoyunlu A, Dulger G. Chemical Composition of Lamium purpureum L. and Determination of Anticancer Activity of Its Essential Oil on Melanoma. DUBİTED. 2019;7:1755–1763.

MLA

Akkoyunlu, Ayşegül, and Gorkem Dulger. “Chemical Composition of Lamium Purpureum L. And Determination of Anticancer Activity of Its Essential Oil on Melanoma”. Duzce University Journal of Science and Technology, vol. 7, no. 3, July 2019, pp. 1755-63, doi:10.29130/dubited.553793.

Vancouver

1.Ayşegül Akkoyunlu, Gorkem Dulger. Chemical Composition of Lamium purpureum L. and Determination of Anticancer Activity of Its Essential Oil on Melanoma. DUBİTED. 2019 Jul. 1;7(3):1755-63. doi:10.29130/dubited.553793

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Chemical Composition of Lamium purpureum L. and Determination of Anticancer Activity of Its Essential Oil on Melanoma

Abstract

Keywords

Lamium purpureum L.’nin Kimyasal Bileşimi ve Uçucu Yağının İnsan Melanom Kanseri Üzerine Antikanser Aktivitesinin Belirlenmesi

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References

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