Biyoaktif Yeni Benzimidazol Aren Rutenyum Organometalik Bileşiğinin Sentezi ve Karakterizasyonu
Abstract
Keywords
Aren rutenyum,Benzimidazol,Organometalik kimya,Termal bozunma,Biyoaktif,Sentez
Supporting Institution
Project Number
Thanks
References
- [1] M. J. Hannon, “Metal-based anticancer drugs: From a past anchored in platinum chemistry to a post-genomic future of diverse chemistry and biology,” Pure and Applied Chemistry, vol. 79, no. 12, pp. 2243–2261, 2007.
- [2] S. Ghosh, “Cisplatin: The first metal based anticancer drug,” Bioorganic Chemistry, vol. 88, no. 1295, pp.1-20, 2019.
- [3] A. A. Nazarov, C. G. Hartinger and P. J. Dyson, “Opening the lid on piano-stool complexes: An account of ruthenium(II)-arene complexes with medicinal applications,” Journal of Organometallic Chemistry, vol. 751, pp. 251-260, 2014.
- [4] L. A. Malley, “Cisplatin,” in Encyclopedia of Toxicology, 3rd ed., vol. 1, National Library of Medicine, Bethesda, USA, 2005, pp. 614-616.
- [5] E. Orhan, A. Garci and B. Therrien, “Coordination-driven self-assembly of arene ruthenium metalla-rectangles,” Inorganica Chimica Acta, vol. 461, pp. 78–83, 2017.
- [6] E. Orhan, A. Garci, T. Riedel, P. J. Dyson and B. Therrien, “Cytotoxicity of arene ruthenium metalla-rectangles incorporating bis-pyridyl diimide linkers,” Journal of Organometallic Chemistry, vol. 815-816, pp. 53-58, 2016.
- [7] A. Grozav, V. Miclaus, O. Vostinaru, S. Ghibu, C. Berce, I. Rotar, C. Mogosan, B. Therrien, F. Loghin and D. Popa, “Acute toxicity evaluation of a thiazolo arene ruthenium (II) complex 2 in rats,” Regulatory Toxicology and Pharmacology, vol. 80, pp. 233-240, 2016.
- [8] O. Renier, C. Deacon-Price, J. E. B. Peters, K. Nurekeyeva, C. Russon, S. Dyson, S. Ngubane, J. Baumgartner, P. J. Dyson, T. Riedel, H. Chiririwa and B. Blom, “Synthesis and in vitro (anticancer) evaluation of η6-arene ruthenium complexes bearing stannyl ligands,” Inorganics, vol. 5, no. 4, pp. 1-13, 2017.
- [9] W. Kandioller, C. G. Hartinger, A. A. Nazarov, J. Kasser, R. John, M. A. Jakupec, V. B. Arion, P. J. Dyson and B. K. Keppler, “Tuning the anticancer activity of maltol-derived ruthenium complexes by derivatization of the 3-hydroxy-4-pyrone moiety,” Journal of Organometallic Chemistry, vol. 694, no. 6, pp. 922-929, 2009.
- [10] N. Mohan, M. K. M. Subarkhan and R. Ramesh, “Synthesis, antiproliferative activity and apoptosis-promoting effects of arene ruthenium(II) complexes with N, O chelating ligands,” Journal of Organometallic Chemistry, vol. 859, pp. 124-131, 2018.