Rare Intraoral White Spongeous Nevus: A Case Report

Abstract

White sponge nevus (WSN) is a rare autosomal dominant hereditary genodermatosis that predominantly affects non-keratinized mucosal surfaces. It is characterized by bilateral, thickened white plaques on the oral mucosa and may clinically resemble other white lesions. Therefore, in order to establish an accurate diagnosis, histopathological evaluation is required in addition to anamnesis and clinical findings. A male patient in his thirties presented to our clinic with complaints of widespread lesions in the oral cavity. Intraoral examination revealed asymptomatic white plaques, particularly prominent on the bilateral buccal mucosa. Based on the clinical and histopathological findings, the patient was diagnosed with WSN. The patient was treated with a 0.25% tetracycline mouth rinse for 12 weeks. At the follow-up visits, although a subjective reduction in lesion thickness was observed based on intraoral examination and comparison of serial photographs, no definitive conclusion can be drawn regarding treatment efficacy.

Keywords

• White sponge nevus
• autosomal dominant
• white plaque
• keratin 13
• keratin 4

Nadir Oral Beyaz Sünger Nevüsü: Bir Olgu Sunumu

Abstract

Beyaz sünger nevüsü (WSN), başlıca keratinize olmayan mukozal yüzeyleri etkileyen, nadir görülen otozomal dominant kalıtsal bir genodermatozdur. Oral mukozada bilateral, kalınlaşmış beyaz plaklarla karakterizedir ve klinik olarak diğer beyaz lezyonlara benzerlik gösterebilir. Bu nedenle doğru tanının konulabilmesi için anamnez ve klinik bulguların yanı sıra histopatolojik değerlendirme gereklidir. Otuzlu yaşlarda erkek hasta, ağız boşluğunda yaygın lezyonlar şikâyetiyle kliniğimize başvurdu. İntraoral muayenede, özellikle bilateral bukkal mukozada belirgin asemptomatik beyaz plaklar gözlendi. Klinik ve histopatolojik bulgular doğrultusunda hastaya WSN tanısı konuldu. Hastaya 12 hafta süreyle %0,25’lik tetrasiklin gargara tedavisi uygulandı. Takip randevularında, intraoral muayene ve seri fotoğrafların karşılaştırılması sonucunda lezyon kalınlığında subjektif bir azalma gözlenmiş olmakla birlikte, tedavi etkinliği hakkında kesin bir sonuca varılamamıştır.

Keywords

• beyaz süngerimsi nevus
• otozomal dominant
• beyaz plak
• keratin 13
• keratin 4

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