Yıl 2019, Cilt 9 , Sayı 2, Sayfalar 128 - 132 2019-08-08

Assessment of Inflammatory Biomarkers, Total IgE levels, SNOT-22 scores in Allergic Rhinitis patients

Demet Yazıcı [1]


Objectives: The aim of this study is to assess neutrophil-lymphocyte ratio (NLR), mean platelet volume (MPV), platelet-lymphocyte ratio (PLR) and eosinophil-lymphocyte ratio (ELR) of allergic rhinitis patients and compare our findings with healthy controls. We also analyzed the effect of severity of allergic rhinitis on hematological parameters and total IgE levels of the patients.

 

Methods: A total of forty-six patients diagnosed having allergic rhinitis according to Allergic Rhinitis and its Impact on Asthma (ARIA) criteria and forty-six healthy, age and sex-matched subjects were included in this study. The clinical records of the patients were retrospectively analyzed and age, gender, skin prick test results, complete blood counts, total IgE levels and Sino-Nasal Outcome Test (SNOT) 22 scores were recorded for assessment of neutrophil-lymphocyte ratio (NLR), mean platelet volume (MPV), platelet-lymphocyte ratio (PLR) and eosinophil-lymphocyte ratio (ELR) of the patients.

 

Results: Eosinophil count, eosinophil percentage and ELR value of the study group were significantly higher than the control group. (p=0,001, p=0,001, p=0,001 respectively) The cut-off value for ELR was ≥0,105. (sensitivity=0,61, specificity=0,76, AUC=0,703) Total IgE levels of patients with positive skin prick test were significantly higher than patients with negative skin prick test. (p=0,019) The cut-off value for total IgE was ≥63 IU/mL. (sensitivity=0,59, specificity=0,74, AUC=0,706).

 

Conclusion: ELR is a valuable marker for predicting allergic rhinitis. However, it does not correlate with the severity of the disease. Total IgE levels increase in patients with positive skin prick tests. Also, total IgE level does not correlate with the severity of allergic rhinitis.  

Allergic rhinitis, biomarker, eosinophil
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Birincil Dil en
Konular Sağlık Bilimleri ve Hizmetleri
Bölüm Makaleler
Yazarlar

Orcid: 0000-0002-5726-1987
Yazar: Demet Yazıcı (Sorumlu Yazar)
Kurum: Adana Şehir Eğitim ve Araştırma Hastanesi
Ülke: Turkey


Tarihler

Başvuru Tarihi : 23 Haziran 2019
Kabul Tarihi : 24 Temmuz 2019
Yayımlanma Tarihi : 8 Ağustos 2019

Bibtex @araştırma makalesi { entupdates581445, journal = {ENT Updates}, issn = {2149-7109}, eissn = {2149-6498}, address = {}, publisher = {Sürekli Eğitim ve Bilimsel Araştırmalar Derneği}, year = {2019}, volume = {9}, pages = {128 - 132}, doi = {10.32448/entupdates.581445}, title = {Assessment of Inflammatory Biomarkers, Total IgE levels, SNOT-22 scores in Allergic Rhinitis patients}, key = {cite}, author = {Yazıcı, Demet} }
APA Yazıcı, D . (2019). Assessment of Inflammatory Biomarkers, Total IgE levels, SNOT-22 scores in Allergic Rhinitis patients. ENT Updates , 9 (2) , 128-132 . DOI: 10.32448/entupdates.581445
MLA Yazıcı, D . "Assessment of Inflammatory Biomarkers, Total IgE levels, SNOT-22 scores in Allergic Rhinitis patients". ENT Updates 9 (2019 ): 128-132 <https://dergipark.org.tr/tr/pub/entupdates/issue/47766/581445>
Chicago Yazıcı, D . "Assessment of Inflammatory Biomarkers, Total IgE levels, SNOT-22 scores in Allergic Rhinitis patients". ENT Updates 9 (2019 ): 128-132
RIS TY - JOUR T1 - Assessment of Inflammatory Biomarkers, Total IgE levels, SNOT-22 scores in Allergic Rhinitis patients AU - Demet Yazıcı Y1 - 2019 PY - 2019 N1 - doi: 10.32448/entupdates.581445 DO - 10.32448/entupdates.581445 T2 - ENT Updates JF - Journal JO - JOR SP - 128 EP - 132 VL - 9 IS - 2 SN - 2149-7109-2149-6498 M3 - doi: 10.32448/entupdates.581445 UR - https://doi.org/10.32448/entupdates.581445 Y2 - 2019 ER -
EndNote %0 ENT Updates Assessment of Inflammatory Biomarkers, Total IgE levels, SNOT-22 scores in Allergic Rhinitis patients %A Demet Yazıcı %T Assessment of Inflammatory Biomarkers, Total IgE levels, SNOT-22 scores in Allergic Rhinitis patients %D 2019 %J ENT Updates %P 2149-7109-2149-6498 %V 9 %N 2 %R doi: 10.32448/entupdates.581445 %U 10.32448/entupdates.581445
ISNAD Yazıcı, Demet . "Assessment of Inflammatory Biomarkers, Total IgE levels, SNOT-22 scores in Allergic Rhinitis patients". ENT Updates 9 / 2 (Ağustos 2019): 128-132 . https://doi.org/10.32448/entupdates.581445
AMA Yazıcı D . Assessment of Inflammatory Biomarkers, Total IgE levels, SNOT-22 scores in Allergic Rhinitis patients. ENT Updates. 2019; 9(2): 128-132.
Vancouver Yazıcı D . Assessment of Inflammatory Biomarkers, Total IgE levels, SNOT-22 scores in Allergic Rhinitis patients. ENT Updates. 2019; 9(2): 132-128.