Evaluation of demineralization changes utilizing the Canary Caries Detection System and various toothpastes on incipient enamel lesions
Abstract
Purpose The Canary Caries Detection System has been shown to quantify the degree of demineralization of incipient enamel. The objective of this study was to evaluate and compare demineralization changes after applying various toothpastes on incipient enamel lesions utilizing the Canary Caries Detection System.
Materials and Methods Thirty-five extracted human teeth premolars were divided into seven groups (n=5). Each group was demineralized in a lactate acid buffer solution (pH 4.5) and tested using one of six toothpastes or a phosphate buffer solution (control, pH 7.4). The teeth were brushed according to manufacturer’s instructions daily for 28 days. Canary Numbers, standardized cold light, and fluorescent photographs were collected at the initial (T0), following demineralization (T1), day 14 (T2), and day 28 (T3).
Results It was found that there was a statistical difference between all groups and the control between T2-T3 (p<0.046 facial surfaces) and T1-T3 (p<0.015 lingual surfaces). There was also a statistical difference between T1-T3 when comparing all groups. The cold light and fluorescent light photos also show evidence of changes in demineralization from T1-T3 in the PreviDent 5000 Plus group.
Conclusion The PreviDent 5000 Plus group demonstrated a statistical difference to Clinpro 5000, MI Paste Plus and PreviDent 5000 Booster Plus from T1-T3 as the Canary Numbers decreased. There was an increase and significant difference in the PBS group Canary Numbers from T1-T3, indicating the negative control showed continued demineralization.
Keywords
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Details
Primary Language
English
Subjects
Dental Materials and Equipment
Journal Section
Research Article
Authors
Skylar Steel
0000-0003-4804-0186
United States
Htwe Mon
0000-0002-4961-8966
United States
Xiaoming Xu
0000-0003-1348-5863
United States
Andrew Chapple
0000-0001-5332-2730
United States
Hope Grandy
0000-0002-6734-6458
United States
Richard Ballard
*
0000-0001-7710-2011
United States
Paul Armbruster
0000-0001-7715-5631
United States
Publication Date
May 20, 2026
Submission Date
November 1, 2024
Acceptance Date
March 1, 2025
Published in Issue
Year 2026 Volume: 60 Number: 1