Yıl 2019, Cilt 7 , Sayı , Sayfalar 296 - 307 2019-11-24

Study the Effect of Isolated Osteocalcin from Human and Rats on Lipids Profile in Normal and Alloxan-Induced Diabetic Male Rats

Thikra AL- ALLWSH [1] , Liqa'a ABDULLA [2]


This study concerned with an attempts to isolate and purify osteocalcin from healthy human blood plasma and healthy rats serum using different biochemical techniques. This included precipitation by cold acetone and gel filtration chromatography. It was found that only the second peak (peak B) from human and rats had concentration of osteocalcin, and showed that fold of purification of isolated osteocalcin 57 and 43 for human and rats respectively. The research also included study the effect of isolated osteocalcin from human plasma and rats serum on lipids profile in normal and alloxan induced diabetic males rats. The results showed after one week of treatment by the isolated osteocalcin from human plasma and rats serum at the dose (1ng/Kg of body weight/d) caused a significant decrease in the concentration of all from total lipids, total cholesterol, triglycerides, VLDL-C, LDL-C, atherogenic index, and a significant increase in the concentration of HDL-C, and antiatherogenic index in normal and alloxan induced diabetic rats.
Osteocalcin, Isolation, Lipids profile, Diabetes, Rats
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Birincil Dil en
Konular Mühendislik
Bölüm Makaleler
Yazarlar

Yazar: Thikra AL- ALLWSH
Kurum: University of Mosul
Ülke: Iraq


Yazar: Liqa'a ABDULLA
Kurum: University of Mosul
Ülke: Iraq


Tarihler

Yayımlanma Tarihi : 24 Kasım 2019

Bibtex @araştırma makalesi { epstem656413, journal = {The Eurasia Proceedings of Science Technology Engineering and Mathematics}, issn = {}, eissn = {2602-3199}, address = {isresoffice@gmail.com}, publisher = {ISRES Organizasyon Turizm Eğitim Danışmanlık Ltd. Şti.}, year = {2019}, volume = {7}, pages = {296 - 307}, doi = {}, title = {Study the Effect of Isolated Osteocalcin from Human and Rats on Lipids Profile in Normal and Alloxan-Induced Diabetic Male Rats}, key = {cite}, author = {AL- ALLWSH, Thikra and ABDULLA, Liqa'a} }
APA AL- ALLWSH, T , ABDULLA, L . (2019). Study the Effect of Isolated Osteocalcin from Human and Rats on Lipids Profile in Normal and Alloxan-Induced Diabetic Male Rats. The Eurasia Proceedings of Science Technology Engineering and Mathematics , 7 () , 296-307 . Retrieved from https://dergipark.org.tr/tr/pub/epstem/issue/50288/656413
MLA AL- ALLWSH, T , ABDULLA, L . "Study the Effect of Isolated Osteocalcin from Human and Rats on Lipids Profile in Normal and Alloxan-Induced Diabetic Male Rats". The Eurasia Proceedings of Science Technology Engineering and Mathematics 7 (2019 ): 296-307 <https://dergipark.org.tr/tr/pub/epstem/issue/50288/656413>
Chicago AL- ALLWSH, T , ABDULLA, L . "Study the Effect of Isolated Osteocalcin from Human and Rats on Lipids Profile in Normal and Alloxan-Induced Diabetic Male Rats". The Eurasia Proceedings of Science Technology Engineering and Mathematics 7 (2019 ): 296-307
RIS TY - JOUR T1 - Study the Effect of Isolated Osteocalcin from Human and Rats on Lipids Profile in Normal and Alloxan-Induced Diabetic Male Rats AU - Thikra AL- ALLWSH , Liqa'a ABDULLA Y1 - 2019 PY - 2019 N1 - DO - T2 - The Eurasia Proceedings of Science Technology Engineering and Mathematics JF - Journal JO - JOR SP - 296 EP - 307 VL - 7 IS - SN - -2602-3199 M3 - UR - Y2 - 2020 ER -
EndNote %0 The Eurasia Proceedings of Science Technology Engineering and Mathematics Study the Effect of Isolated Osteocalcin from Human and Rats on Lipids Profile in Normal and Alloxan-Induced Diabetic Male Rats %A Thikra AL- ALLWSH , Liqa'a ABDULLA %T Study the Effect of Isolated Osteocalcin from Human and Rats on Lipids Profile in Normal and Alloxan-Induced Diabetic Male Rats %D 2019 %J The Eurasia Proceedings of Science Technology Engineering and Mathematics %P -2602-3199 %V 7 %N %R %U
ISNAD AL- ALLWSH, Thikra , ABDULLA, Liqa'a . "Study the Effect of Isolated Osteocalcin from Human and Rats on Lipids Profile in Normal and Alloxan-Induced Diabetic Male Rats". The Eurasia Proceedings of Science Technology Engineering and Mathematics 7 / (Kasım 2019): 296-307 .
AMA AL- ALLWSH T , ABDULLA L . Study the Effect of Isolated Osteocalcin from Human and Rats on Lipids Profile in Normal and Alloxan-Induced Diabetic Male Rats. EPSTEM. 2019; 7: 296-307.
Vancouver AL- ALLWSH T , ABDULLA L . Study the Effect of Isolated Osteocalcin from Human and Rats on Lipids Profile in Normal and Alloxan-Induced Diabetic Male Rats. The Eurasia Proceedings of Science Technology Engineering and Mathematics. 2019; 7: 307-296.