PHENOLIC COMPOUNDS DETERMINATION AND ANTIOXIDANT ACTIVITY OF TEUCRIUM CAVERNARUM

Yıl 2019, , 229 - 237, 31.07.2019

Fatih Göğer , Ayla Kaya Muhittin Dinç , Süleyman Doğu Doğu

https://doi.org/10.18036/estubtdc.599094

Öz

ABSTRACT

The current study was aimed to
determine phenolic compounds profile and antioxidant activity of 70% MeOH
extract of Teucrium cavernarum  P.H. Davis which is an endemic plant of
Turkey.

 

According to LC-MS/MS analysis
of the extract, forsythoside A, forsythoside B, luteolin-7-gucoside,
cirsimaritin and cirsiliol were determined as the major compounds. The total
phenolic and radical scavenging activities of the extract were also determined.
According to antioxidant activity results, IC₅₀ value of
1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging effect was determined
as 0.12 ±0.01 mg/mL. 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid)
(ABTS) radical scavenging activity was also determined as 1.2 mM trolox
equivalent (TEAC).

Anahtar Kelimeler

Teucrium cavernarum, Antioxidant activity, LC-MS/MS, Phenolic

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