ANTİOKSİDAN BİLEŞİKLER KAYNAĞI OLARAK BINAHONG BİTKİSİ (Anredera cordifolia (TEN.) STEENIS)

Öz

Binahong (Anredera cordifolia (Ten.) Steenis), uzun zamandan beri popüler tıbbi ilaç endüstrisinde ve etnomedikal uygulamalarda çeşitli hastalıkların tedavisinde kullanılmaktadır. Çeşitli alkaloidler, flavonoidler, saponinler, fenoller ve karakteristik antibakteriyel ve antioksidan etkilere sahip çok miktarda diğer ikincil metabolitleri içermektedir. Bu bileşikler aynı zamanda diyabet ve kusma gibi birçok hastalığın tedavisinde de kullanılmaktadır. Bu nedenle Endonezya halkının yaşamında çok önemli bir yeri ve potansiyel rolü vardır. Bu çalışma, Endonezya'nın etnomedikal sağlık sisteminde kullanımı yüksek olan bitki hakkında önemli ve değerli bilgiler içermektedir.

Anahtar Kelimeler

• Antioksidan
• kimyasallar
• Endonezya
• yaprak
• rizom

AN INTRODUCTION TO BINAHONG (Anredera cordıfolıa (TEN.) STEENIS) AS A SOURCE OF ANTIOXIDANT COMPOUNDS

Abstract

Binahong (Anredera cordifolia (Ten.) Steenis), is a popular medicinal plant of Indonesia used in pharmaceutical industries and for treating various diseases in ethno medicinal practices for a long time. It contains several alkaloids, flavonoids saponins, phenols, and a large amount of other secondary metabolites that have characteristic antibacterial and antioxidant effects. These compounds are also used to treat many diseases like diabetes and vomiting etc. Therefore, it has a very important place and potential role in the life of the Indonesian people. This study provides important and valuable informations about the plant that has high utilization in the ethno medicinal care system of Indonesia.

Keywords

• Antioxiant
• Chemicals
• Indonesia
• leaf
• rhizome

References

1. Astuti, S. M., Mimi Sakinah A.M., Retno Andayani B.M., & Awalludin R. (2011). Determination of saponin compound from (Anredera cordifolia (Ten). Steenis.) Plant (Binahong) to Potential Treatment for Several Diseases. J. Agric. Sci. 3(4) 224-232.
2. Backer, C.A., & van de Brink, B. (1963). Flora of Java, N.V.P. Noordhoff, Groningen, The Netherlands, 1(3):191-238.
3. Balai Penelitian Tanaman Rempah dan Obat (BALITTRO), (2006). Rencana dan strategis Balai Penelitian Tanaman Obat dan Aromatik 2006-2009. Bogor, Indonesia (In Indonesian Language).
4. BPOM RI-Direktorat Obat Asli Indonesia (2008). Anredera cordifolia (Ten.) Steenis. http://perpustakaan.pom.go.id/ebook/Taksonomi%20Koleksi%20Tanaman %20Obat%20Kebun%20Tanaman%20Obat%20Citeureup/Anredera%20cordifolia%C2%A0%C2%A0(Ten.)%20Steenis.pdf (Accession date: 21 03. 2023).
5. Feriyani, F., Darmawi, D., Balqis, U., Lubis, R.R. (2020). The Analysis of Binahong Leaves Potential (Anredera cordifolia) as an Alternative Treatment of Anticataractogenesis. Open Access Maced J Med Sci. 20 (8): 8 (B):820-824. https://doi.org/10.3889/oamjms.2020.4849
6. Fidrianny, I., Wirasutisna, K.R., & Amanda, P. (2013) Senyawa antioksidan dari ekstrak etil asetat daun binahong (Anredera cordifolia (Ten.) Steenis) dari babakan ciparay, Bandung Selatan, Indonesia. Acta Pharm. Indonesia. 2013;38(1):26-30. https://doi. org/10.32382/mf.v15i2.1127
7. Goleniowski, M., Bonfill, M., Cusido, R., Palazón, J. (2013). Phenolic Acids. In: Ramawat, K., Mérillon, JM. (eds) Natural Products. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-22144-6_64
8. Hanafiah, O.A., Hanafiah, D.S., Bayu, E.S., Abidin, T., Ilyas S., Nainggolan M. & Syamsudin, E. (2017). Quantity differences of secondary metabolites (saponins, tannins and flavonoids) from Binahong plant extract (Anredera cordifolia (Ten.) Steenis) treated and untreated with Colchicines that play a role in wound healing. World J. Dent., 8: 296-

9. Manoi, F. (2009). Binahong Anredera cordifolia (Ten) Steenis. Sebagai Obat. J. Warta Penelit. Pengemb. Tan. Industri. 15(1):3-5. (In Indonesia Language).
10. Miladiyah, I., & Prabowo, B. R. (2012). Ethanolic extract of Anredera cordifolia (Ten.) Steenis leaves improved wound healing in guinea pigs. Universa Medicina, 31(1): 4-11.
11. Octavia, D.R. (2009), Uji Aktivitas Penangkap Radikal Ekstrak Petroleum Eter, Etil Asetat, dan Etanol Daun Binahong Anredera cordifolia (Tenore) Steenis. dengan Metode DPPH (2,2-difenil-1-pikrilhidrazil), skripsi sarjana, Fakultas Farmasi Universitas Muhammadiyah Surakarta, Surakarta, 3-21. (In Indonesia Language).
12. PIER. (Pasific Island Ecosystem at Risk). (2000). Insasive Plant Species: Anradera cordifolia. Available: http://www.hear.org/pier/ancor.htm (Acceses date: October 21, 2021).
13. PROSEA.(2003). Plant Resources of South-East Asia : Medicinal and Poisonous Plant 3. In de Padua, L.S., Bunyapraphatsara and Lemmens, R.H.M.J (Eds.). PROSEA Indonesia. Bogor. 2 (15):128-133.
14. Rooban, B.N., Sasikala, V., Devi, V.G., Sahasranamam, V., Abraham, A., (2012) Prevention of selenite induced oxidative stress and cataractogenesis by luteolin isolated from Vitex negundo. Chem. Biol. Interact. 196 (1-2):30-8.
15. Sukrama, D.M, Wihandani D.M. & Manuaba, A.P. (2016). Topical Binahong (Anredera cordifolia) leaf extract increases interleukin-6 and VEGF during burn wound healing in Wistar rats infected with Pseudomonas aeruginosa. Biol. Med., Vol. 9.
16. Takahashi, M., Asikin Y., Takara K. & Wada, K. (2012). Screening of medicinal and edible plants in Okinawa, Japan, for enhanced proliferative and collagen synthesis activities in NB1RGB human skin fibroblast cells. Biosci. Biotechnol. Biochem., 76: 2317-2320.
17. Tjitrosoepomo, G. (1999). Morfologi Tumbuhan. Gadjah Mada University Press. Yogyakarta. pp 218-251 (In Indonesia Language).
18. Tshikalange, T.E., Meyer J.J.M., & Husein, A.A. (2005). Antimicrobial activity, toxicity and the isolation of a bioactive compound from plants used to treat sexually transmitted diseases. J. Ethno pharmacol. 96:515-519.
19. Wagner, W.L., Herbst, D.R., & Sohmer, S.H. (1999). Manual of the Flowering Plants of Hawai’i. 2 Vols. Bishop Museum Special Publication 83.
20. Wang, T., Zhang, P., Zhao, C., Zhang, Y., Liu, H., Hu, L., Gao, X, Zhang, D. (2011). Prevention effect in selenite-induced cataract in vivo and antioxidative effects in vitro of Crataegus pinnatifida leaves. Biol. Trace. Elem. Res. 2011;142(1):106-16.
21. Winarsi, H., (2011). Antioksidan Alami dan Radikal Bebas, Penerbit Kanisius, Yogyakarta, 15(21): 79-82. (In Indonesia Language).
22. Yang, R., Y, Lin, S., Kuo, G. Content and distribution of flavonoids among 91 edible plant species. Asia Pac J Clin Nutr. 2008;17 Suppl 1:275-9. PMID: 18296355.
23. Yuziani, Y., Harahap U. & Karsono, K. (2014). Evaluation of analgesic activities of ethanolic extract of Anredera cordifolia (Ten) steenis leaf. Int. J. Pharm. Tech. Res., 6: 1608-1610.