A Fourier Transform Infrared Spectrophotometry Method Used For Oseltamivir Determination in Pharmaceutical Formulations
Abstract
A Fourier transform infrared (FT-IR) spectrometric method was developed for the rapid, direct measurement of oseltamivir phosphate (OP) in pharmaceutical formulations. Conventional KBr-spectra were compared for best determination of the active substance in pharmaceutical preparations. The Beer-Lambert law and two chemometric approaches, partial least squares (PLS) and principal component regression (PCR+) methods, were used in data processing.
Key words: FT-IR analysis, oseltamivir, chemometric methods, pharmaceutical analysis.
References
- USP XXII (United States Pharmacopoeia, 22nd revision), Convection Inc., Rockville, MD, 809, (1990).
- Moffat A.C. (ed.), Clarke’s Isolation and Identification Pharmaceutical Society of Great Britain, London, (1986). 2nd Ed., The 3. Ciurczak, E.W. and Pharmaceutical and medical Applications of Near- Infrared Spectroscopy, Marcel Dekker, Inc., New York, 73-105 (2001). Drennen, J.K.III, 4. McClure, W.F., Analysis Fransforms, in Handbook of Near-Infrared Analysis, Burns, D.A. and Ciurczak, E.W., eds, Marcel Dekker, Inc., New York, 181-274 (1992).
- Garrigues, S., Gallignani, M. and de la Guardia, M. Simultaneous determination of ortho-, meta- and transform 117:1849-1853 (1992).
- injection-Fourier infrared Analyst,
- Miller, B.E., Danielson, N.D. and Katon, J.E. Aqueous Infrared Pharmaceutical Analysis of Two Choline Compounds by Flow Injection Analysis Using the CIRCLE Cell, Appl. Spectrosc., 42, 401-405 (1988).
- Bunaciu, A.A., Aboul-Enein, H.Y.and Fleschin, S. Application of
- Fourier Transform Infrared spectrometry in pharmaceutical drugs analysis, Applied Spectroscopy Reviews, , 45, 206-219 (2010).
- Laborde-Kummer, E., Gaudin, K., Joseph- Charles, J., Gheyouche, R. Boudis, H., Dubost, J- P., Development and validation of a rapid capillary electrophoresis method for the determination of oseltamivir phosphate in Tamiflu® and generic versions, J. Pharm. Biomed.Anal., 50, 544-546 (2009).
- Haleblian, J. and McCrone W., Pharmaceutical applications of polymorphism, J. Pharm.Sci., , 58, 911-929 (1969).
- Luinge, H.J., Hop, E., Lutz, E.T., van Hemert J.A. and de Jong, E.A., Determination of the fat, protein and lactose content of milk using Fourier transform infrared spectrometry, Anal.Chim.Acta, 284, 419-433 (1993).
- Wold, H., Research Papers in Statistics, ed. David F.N., Wiley, New York, (19669.
- Geladi, P. and Kowalski, B.R. Partial least-squares regression: a tutorial Anal.Chim.Acta, , 185, 1-17. (1986).
Year 2012,
Volume: 25 Issue: 3, 631 - 634, 06.02.2012
Abstract
References
- USP XXII (United States Pharmacopoeia, 22nd revision), Convection Inc., Rockville, MD, 809, (1990).
- Moffat A.C. (ed.), Clarke’s Isolation and Identification Pharmaceutical Society of Great Britain, London, (1986). 2nd Ed., The 3. Ciurczak, E.W. and Pharmaceutical and medical Applications of Near- Infrared Spectroscopy, Marcel Dekker, Inc., New York, 73-105 (2001). Drennen, J.K.III, 4. McClure, W.F., Analysis Fransforms, in Handbook of Near-Infrared Analysis, Burns, D.A. and Ciurczak, E.W., eds, Marcel Dekker, Inc., New York, 181-274 (1992).
- Garrigues, S., Gallignani, M. and de la Guardia, M. Simultaneous determination of ortho-, meta- and transform 117:1849-1853 (1992).
- injection-Fourier infrared Analyst,
- Miller, B.E., Danielson, N.D. and Katon, J.E. Aqueous Infrared Pharmaceutical Analysis of Two Choline Compounds by Flow Injection Analysis Using the CIRCLE Cell, Appl. Spectrosc., 42, 401-405 (1988).
- Bunaciu, A.A., Aboul-Enein, H.Y.and Fleschin, S. Application of
- Fourier Transform Infrared spectrometry in pharmaceutical drugs analysis, Applied Spectroscopy Reviews, , 45, 206-219 (2010).
- Laborde-Kummer, E., Gaudin, K., Joseph- Charles, J., Gheyouche, R. Boudis, H., Dubost, J- P., Development and validation of a rapid capillary electrophoresis method for the determination of oseltamivir phosphate in Tamiflu® and generic versions, J. Pharm. Biomed.Anal., 50, 544-546 (2009).
- Haleblian, J. and McCrone W., Pharmaceutical applications of polymorphism, J. Pharm.Sci., , 58, 911-929 (1969).
- Luinge, H.J., Hop, E., Lutz, E.T., van Hemert J.A. and de Jong, E.A., Determination of the fat, protein and lactose content of milk using Fourier transform infrared spectrometry, Anal.Chim.Acta, 284, 419-433 (1993).
- Wold, H., Research Papers in Statistics, ed. David F.N., Wiley, New York, (19669.
- Geladi, P. and Kowalski, B.R. Partial least-squares regression: a tutorial Anal.Chim.Acta, , 185, 1-17. (1986).
There are 12 citations in total.
Details
| Primary Language | English |
|---|---|
| Authors | |
| Publication Date | February 6, 2012 |
| IZ | https://izlik.org/JA82DJ78YR |
| Published in Issue | Year 2012 Volume: 25 Issue: 3 |