An efficient synthesis of 3-aryl-2-cyclohexylamino-6,7-dihydro-1H-indole-4(5H)-ones using ferric perchlorate as the catalyst via four-component reaction between cyclohexylisocyanide, an aldehyde, a cyclic 1,3-dicarbonyl compound and ammonium acetate in acetonitrile is described.
Key Words: cyclohexylisocyanide, cyclic 1,3-dicarbonyl compound, multi-component reaction;1H-Indole-4(5H)-ones.
Primary Language | English |
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Journal Section | Chemistry |
Authors | |
Publication Date | March 8, 2010 |
Published in Issue | Year 2010 Volume: 23 Issue: 1 |