This study includes the design, synthesis and characterization of 1,2-phenylenediamine (o-PDA) functionalized maleic anhydride (MA)-vinyl acetate (VA) copolymer-based conjugate to develop a new formulation. The 1,2-phenylenediamine molecule is a fluorescent dye that allows designing new chemotherapeutic polymeric molecules. Poly(maleic anhydride-alt-vinyl acetate) [Poly(MA-alt-VA)] was obtained via charge transfer complex (CTC) radical polymerization presence of methyl ethyl ketone (MEK), utilizing benzoyl peroxide (BPO) free-radical initiator at 80 °C, as a potential functional polymeric carrier. Structural characterization of the surface functionalized poly(MA-alt-VA)/1,2-PDA conjugate was performed by Attenuated Total Reflectance-Fourier Transform Infrared (ATR-FTIR) and Nuclear Magnetic Resonance (1H-NMR). Spectroscopic methods and water solubility results confirmed that the conjugation took place successfully after the ring opening reaction by the amidation mechanism.
poli(MA-alt-VA) Surface modification 1 2-phenylenediamine ATR-FTIR 1H-NMR
Birincil Dil | İngilizce |
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Konular | Mühendislik |
Bölüm | Research Articles |
Yazarlar | |
Yayımlanma Tarihi | 31 Aralık 2022 |
Gönderilme Tarihi | 9 Kasım 2022 |
Yayımlandığı Sayı | Yıl 2022 Cilt: 9 Sayı: 4 |
Hittite Journal of Science and Engineering Creative Commons Atıf-GayriTicari 4.0 Uluslararası Lisansı (CC BY NC) ile lisanslanmıştır.